Results 201 to 210 of about 66,266 (300)

RTEL1 mutation modifies dyskeratosis congenita caused by a telomerase RNA template mutation. [PDF]

Nat Commun
Deimler N, Orioli A, Holthöfer L, Linke M, Bobon N, Engelhardt V, Erichsen L, Paul NW, Meyer R, Beier F, Schweiger S, Baumann P.   +11 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Characterization of post-mitotic DNA synthesis and its regulation in human cells. [PDF]

Nat Commun
Vornberger J, Imhof R, Pasti V, Bianchi B, Wei M, Straw JA, Manohar S, Altmeyer M.   +7 more
europepmc   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Molecular markers, mechanisms and metrics of biological aging: a scoping review. [PDF]

Front Aging
Ziesel A, Reeves J, Mallidou A, Newton L, Rhodes RE, Zhang J, Paterson T, Jabbari H.   +7 more
europepmc   +1 more source

Phloridzin Mitigates Aging‐Associated Periodontitis by Restraining Inflammatory Cell Death

Journal of Periodontal Research, EarlyView.
Phloridzin attenuated oxidative stressinduced senescence, inflammatory responses, and osteogenic dysfunction in HPDLCs. In an aging‐associated experimental periodontitis model, phloridzin alleviated alveolar bone loss, suggesting its potential to maintain periodontal tissue integrity under aging‐related inflammatory conditions.
Da Eun Lee, Eun‐Nam Kim, Gil‐Saeng Jeong   +2 more
wiley   +1 more source

The Role of Actin-Filament Bundling Protein, Fimbrin Sac6, and Type-V Myosin Myo2, in the Motion of the SUN-Domain Protein, Mps3, During Yeast Meiosis. [PDF]

Genes Cells
Cheng S, Nozaki T, Fujita Y, Ito M, Shinohara A.   +4 more
europepmc   +1 more source

Oral Lichenoid Lesions in Patients With Dyskeratosis Congenita: A Retrospective Case Series

Oral Diseases, EarlyView.
ABSTRACT Background Dyskeratosis congenita (DKC) is a rare inherited multisystem disorder primarily affecting the mucocutaneous and hematopoietic systems. Classically, it presents with the ectodermal triad of reticulate skin pigmentation, nail dystrophy, and oral leukoplakia.
Yehuda Zadik, Ori Finfter, Tevel Amiel, Amina Massarwa, Refael Cohen, Jawad Abu Tair, Anna Novikov, Polina Stepensky, Irina Zaidman, Ehud Even‐Or   +9 more
wiley   +1 more source

Human length telomeres restrict the regenerative potential of hematopoietic stem cells in mice. [PDF]

J Biol Chem
Rowe MM, Tober J, Ortiz V, Smoom R, Tzfati Y, Speck N, Kaestner KH.   +6 more
europepmc   +1 more source

Malignant Transformation in Oral Potentially Malignant Disorders

Oral Diseases, EarlyView.
ABSTRACT Background In 2020, the World Health Organization (WHO) Collaborating Centre for Oral Cancer convened an international expert workshop to establish an updated consensus on the nomenclature and classification of oral potentially malignant disorders (OPMDs).
Miguel Ángel González‐Moles, Pablo Ramos‐García, Saman Warnakulasuriya   +2 more
wiley   +1 more source