ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou +12 more
wiley +1 more source
Decoding the significance of TERT gene in Polycystic Ovary Syndrome: From molecular mechanisms to emerging diagnostic and therapeutic strategies. [PDF]
Balgote PJ +3 more
europepmc +1 more source
The Nuclease Activity of Mre11 Is Required for Meiosis but Not for Mating Type Switching, End Joining, or Telomere Maintenance [PDF]
Sylvie Moreau +2 more
openalex +1 more source
Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao +6 more
wiley +1 more source
Reduced CHMP7 Expression Compromises Telomere Integrity in Mammalian Cells. [PDF]
Burla R +5 more
europepmc +1 more source
A high-throughput method for quantifying relative telomere length in single cells in situ combined with live-cell imaging. [PDF]
Sun Q, Zou Z, Min M.
europepmc +1 more source
ABSTRACT Belamcanda chinensis is a non‐leguminous medicinal plant rich in bioactive isoflavones; however, the lack of a high‐quality reference genome has limited elucidation of its isoflavone biosynthetic and modification network. Here, we present the first near telomere‐to‐telomere genome assembly of B.
Yuan‐Yuan Wang +10 more
wiley +1 more source
The alternative lengthening of telomeres pathway through a DNA repair lens: mechanism and therapeutic opportunities. [PDF]
Muoio D, Fouquerel E.
europepmc +1 more source
Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance [PDF]
Yulia V. Surovtseva +5 more
openalex +1 more source

