Results 231 to 240 of about 59,567 (314)

Genes shielded, repeats exposed: mutation bias in the midge Chironomus riparius. [PDF]

G3 (Bethesda)
Nieto-Blázquez ME, Pfenninger M.
europepmc   +1 more source

Decoding the significance of TERT gene in Polycystic Ovary Syndrome: From molecular mechanisms to emerging diagnostic and therapeutic strategies. [PDF]

J Ovarian Res
Balgote PJ, Nowshad F, Patnaik A, Sivaraman J.   +3 more
europepmc   +1 more source

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Reduced CHMP7 Expression Compromises Telomere Integrity in Mammalian Cells. [PDF]

Cells
Burla R, La Torre M, Maccaroni K, Tacconi S, Dini L, Saggio I.   +5 more
europepmc   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source

A high-throughput method for quantifying relative telomere length in single cells in situ combined with live-cell imaging. [PDF]

J Mol Cell Biol
Sun Q, Zou Z, Min M.
europepmc   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

The alternative lengthening of telomeres pathway through a DNA repair lens: mechanism and therapeutic opportunities. [PDF]

NAR Cancer
Muoio D, Fouquerel E.
europepmc   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

A mechanism for telomere-specific telomere length regulation. [PDF]

Nucleic Acids Res
Teplitz GM, Pasquier E, Bonnell E, De Laurentiis E, Bartle L, Lucier JF, St-Laurent G, Dawson DS, Wellinger RJ.   +8 more
europepmc   +1 more source