A phase 1b/2 study of cabozantinib in combination with pembrolizumab in advanced cutaneous melanoma
Abstract Background Pembrolizumab is approved for advanced cutaneous melanoma (aCM). Cabozantinib, an oral multi‐tyrosine kinase inhibitor, has demonstrated antitumor activity as monotherapy or in combination with anti‐PD‐1 therapy in malignancies. The objective of this study was to determine the safety and efficacy of cabozantinib and pembrolizumab ...
Yousef Zakharia +10 more
wiley +1 more source
Retraction Note: Magnetic and pH sensitive nanocomposite microspheres for controlled temozolomide delivery in glioblastoma cells. [PDF]
Ahmadi M +6 more
europepmc +1 more source
β‐cyclodextrin‐based multicharged polymers—linear or cross‐linked—enhance the delivery of mitogen‐activated protein kinase inhibitors (selumetinib, trametinib) in glioblastoma cells. These carriers enhance the antiproliferative effect of the drugs and strengthen extracellular signal‐regulated kinase pathway inhibition.
Noemi Bognanni +6 more
wiley +1 more source
Venous Thromboembolism and Bleeding with Temozolomide-, Bevacizumab-, and Nitrosourea-Based Therapy in Glioma: A Dual-Database Pharmacovigilance Study. [PDF]
Hou X, Zhang Y, Liang C, Yao S.
europepmc +1 more source
Defying the Odds in Recurrent Glioblastoma: Complete Response following Salvage Therapy with Bevacizumab and Irinotecan - A Case Report. [PDF]
Yousefi A, Saraee E, Ghalehtaki R.
europepmc +1 more source
MGMT upregulation mediates Temozolomide resistance conferred USP5 dependency. [PDF]
Bhardwaj S +5 more
europepmc +1 more source
Impact of neuroendocrine neoplasm-specific systemic treatments on expression and function of CXCR4 in neuroendocrine tumor cells. [PDF]
Däubler C +9 more
europepmc +1 more source
Retraction Note: Newcastle disease virus enhances the growth-inhibiting and proapoptotic effects of temozolomide on glioblastoma cells in vitro and in vivo. [PDF]
Bai Y +8 more
europepmc +1 more source
Primary Tumor Size and Tumor-Vessel Interface Following Capecitabine and Temozolomide for Pancreatic Neuroendocrine Tumor. [PDF]
Guo J +15 more
europepmc +1 more source
Effects of temozolomide dosing on outcome in glioblastoma. [PDF]
Raghu A, Killar S, Cohen AL.
europepmc +1 more source

