Results 61 to 70 of about 4,158,929 (341)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Online Monitoring Based on Temperature Field Features and Prediction Model for Selective Laser Sintering Process

Applied Sciences, 2018
Selective laser sintering (SLS) is an additive manufacturing technology that can work with a variety of metal materials, and has been widely employed in many applications.
Zhehan Chen, Xianhui Zong, Jing Shi, Xiaohua Zhang   +3 more
doaj   +1 more source

Numerical and Experimental Reconstruction of Temperature Distribution and Soot Concentration Field for Thin-Slice Flames Using a Charge Coupled Device Camera

Fire, 2023
This work proposed a novel model to simultaneously reconstruct temperature distribution and soot volume fraction field for two-dimensional thin-slice flames using the knowledge of monochromatic radiation intensities at two wavelengths using a CCD camera.
Mingfei Chen, Yun Chen, Tianjiao Li, Dong Liu   +3 more
doaj   +1 more source

Giant magnetic-field changes in radio-frequency absorption in La$_{0.67}$Sr$_{0.33}$MnO$_3$ near the Curie temperature

, 2004
The DC transport properties of and the radio-frequency (RF) wave absorption (at 2.525 MHz) in a sample of La$_{0.67}$Sr$_{0.33}$MnO$_{3}$ prepared by floating-zone method are measured. The Curie temperature, $T_{c}$, of the sample is about 374 K.
A.S. Panfilov, A.Ya. Kirichenko, B.I. Belevtsev, Belevtsev, Belevtsev, Coey, Dagotto, E.Yu. Beliayev, Eremenko, G.V. Golubnichaya, Hu, Hu, I.G. Maximchuk, J. Fink-Finowicki, Knobel, Mukhin, N.T. Cherpak, Smit, Urushibara, Vonsovsky, Wang, Wang, Zhang   +22 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Fire Effect and Performance of Bridge Pylon Columns under Construction

Fire, 2023
The fire effect and performance of bridge pylons under construction were investigated via an analysis conducted on two types of pylons with different wall thicknesses. Three fire scenarios, namely internal fire, external ring fire, and external side fire,
Yang Li, Zuocai Wang, Changjian Wang, Yin Zhang, Hongsheng Ma, Lili Liu   +5 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Influence of angle adjustment of theoutlet blade on thermal comfort

Zhileng xuebao, 2020
The correct outlet blade angle can maximize the capacity of an air-conditioning system and effectively improve the flow field and temperature distribution in the car, thereby greatly improving the thermal comfort of passengers.
Li Siwang, Li Shuai, Feng Hongfei
doaj  

Numerical Simulation of Zr-based Bulk Metallic Glass During Continuous Casting Solidification Process [PDF]

Materials Research, 2015
A numerical simulation method was used to analyze the solidification process of Zr-based bulk metallic glass (BMG) during the horizontal continuous casting (HCC) process.
Renhong Tang, Bingwen Zhou, Yuejiao Ma, Fei Jia, Xingguo Zhang   +4 more
doaj   +2 more sources

A New Multi-Physics Coupled Method for the Temperature Field of Dry Clutch Assembly

Applied Sciences, 2023
The temperature field of the clutch assembly is critical for the clutch design and operation life. Current modeling methods of the temperature of the clutch assembly suffer from insufficient accuracy or a limited time scale for the complicated multi ...
Jun Chen, Jiali Yu, Yubing Gong
doaj   +1 more source