Results 11 to 20 of about 219,031 (288)
Extensive recombination due to heteroduplexes generates large amounts of artificial gene fragments during PCR. [PDF]
PLoS ONE, 2014 Artificial recombinants can be generated during PCR when more than two genetically distinct templates coexist in a single PCR reaction. These recombinant amplicons can lead to the false interpretation of genetic diversity and incorrect identification of ...
Jia Liu +6 more
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An unbiased template of the Drosophila brain and ventral nerve cord.
PLoS ONE, 2020 The fruit fly Drosophila melanogaster is an important model organism for neuroscience with a wide array of genetic tools that enable the mapping of individual neurons and neural subtypes.
John A Bogovic +10 more
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Frontiers in Molecular Biosciences, 2023 Determining the three-dimensional structure of proteins in their native functional states has been a longstanding challenge in structural biology. While integrative structural biology has been the most effective way to get a high-accuracy structure of ...
Davide Sala +4 more
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Scientific Reports, 2022 Rapid, cost-effective identification of genetic variants in small candidate genomic regions remains a challenge, particularly for less well equipped or lower throughput laboratories.
Whitney Whitford +6 more
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Oncogene inference optimization using constraint-based modelling incorporated with protein expression in normal and tumour tissues [PDF]
Royal Society Open Science, 2020 Cancer cells are known to exhibit unusual metabolic activity, and yet few metabolic cancer driver genes are known. Genetic alterations and epigenetic modifications of cancer cells result in the abnormal regulation of cellular metabolic pathways that are ...
Wu-Hsiung Wu +6 more
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Human Head Tracking Based on Particle Swarm Optimization and Genetic Algorithm [PDF]
, 2007 This paper compares particle swarm optimization and a genetic algorithm for perception by a partner robot. The robot requires visual perception to interact with human beings.
Kubota, Naoyuki, Sulistijono, Indra Adji
core +1 more source
Nonenzymatic RNA-templated Synthesis of N3′→P5′ Phosphoramidate DNA
Bio-Protocol, 2020 The RNA world hypothesis describes a scenario where early life forms relied on RNA to govern both inheritance and catalyze useful chemical reactions.
Derek O'Flaherty +2 more
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Bionanomaterials from plant viruses [PDF]
, 2015 Plant virus capsids have emerged as useful biotemplates for material synthesis. All plant virus capsids are assembled with high-precision, three-dimensional structures providing nanoscale architectures that are highly monodisperse, can be produced in ...
Aljabali, Alaa A. A., Evans, David
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Transformation and CRISPR-Cas9-mediated homologous recombination in the fungus Rhizopus microsporus
STAR Protocols, 2022 Summary: Here, we describe a reliable approach for targeted DNA integrations in the genome of R. microsporus, one of the main causal agents of mucormycosis.
Carlos Lax +5 more
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Design, modeling and synthesis of an in vitro transcription rate regulatory circuit [PDF]
, 2008 This paper describes the design, modeling and realization of a synthetic in vitro circuit that aims at regulating the rate of mRNA transcription. Two DNA templates are designed to interact through their transcripts, creating negative feedback loops that ...
Forsberg, Per-Ola +2 more
core +2 more sources