Results 21 to 30 of about 121,448 (310)

Proof of concept for multiplex amplicon sequencing for mutation identification using the MinION nanopore sequencer

Scientific Reports, 2022
Rapid, cost-effective identification of genetic variants in small candidate genomic regions remains a challenge, particularly for less well equipped or lower throughput laboratories.
Whitney Whitford, Victoria Hawkins, Kriebashne S. Moodley, Matthew J. Grant, Klaus Lehnert, Russell G. Snell, Jessie C. Jacobsen   +6 more
doaj   +1 more source

Oncogene inference optimization using constraint-based modelling incorporated with protein expression in normal and tumour tissues [PDF]

Royal Society Open Science, 2020
Cancer cells are known to exhibit unusual metabolic activity, and yet few metabolic cancer driver genes are known. Genetic alterations and epigenetic modifications of cancer cells result in the abnormal regulation of cellular metabolic pathways that are ...
Wu-Hsiung Wu, Fan-Yu Li, Yi-Chen Shu, Jin-Mei Lai, Peter Mu-Hsin Chang, Chi-Ying F. Huang, Feng-Sheng Wang   +6 more
doaj   +1 more source

Comparison of recombination frequencies between templates with high and low genetic diversities. [PDF]

, 2014
Note: 30 cycles of PCR with 1000 copies of each template.Comparison of recombination frequencies between templates with high and low genetic diversities.
Hui Zhuang (139189), Hongshuo Song (598912), Feng Gao (3548), Jia Liu (41593), Donglai Liu (628516), Fengmin Lu (139191), Tao Zuo (350509)   +6 more
core   +1 more source

Multi-site genetic analysis of diffusion images and voxelwise heritability analysis : a pilot project of the ENIGMA–DTI working group [PDF]

, 2013
The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Consortium was set up to analyze brain measures and genotypes from multiple sites across the world to improve the power to detect genetic variants that influence the brain.
Sprooten, Emma, Glahn, David C., Curran, Joanne E., Mandl, R.C., Almasy, L., Kochunov, Peter V., Hulshoff Pol, H.E., Curran, J.E., Starr, John M., Brouwer, Rachel M., Wardlaw, J.M., Mitchell, Braxton D., Brouwer, R.M., Wright, M.J., Bastin, M.E., Mandl, René C., Medland, Sarah E., Glahn, D.C., Sussmann, Jessika E., Medland, S.E., Martin, N.G., McMahon, K.L., Landman, Bennett A., Hulshoff Pol, Hilleke E., Nichols, T.E., Nichols, Thomas E., Toga, Arthur W., Peterson, C.P., Thompson, P.M., Jahanshad, N., Martin, Nicholas G., Wardlaw, Joanna M., Sprooten, E., Mitchell, B.D., McIntosh, A.M.; id_orcid, Pol, Hilleke E. Hulshoff, Hong, L. Elliot, Peterson, Charles P., Deary, Ian J., Hong, L.E., Kochunov, P.V., Jahanshad, Neda, Duggirala, Ravi, Bastin, Mark E., Fox, Peter T., McIntosh, Andrew M., de Zubicaray, G.I., de Zubicaray, Greig I., Landman, B.A., Fox, P.T., Thompson, Paul M., McMahon, Katie L., Blangero, J., Olvera, Rene L., Sussmann, J.E., Olvera, R.L., McIntosh, A.M., Wright, Margaret J., Duggirala, R., Almasy, Laura, Blangero, John, Starr, J.M., Toga, A.W., Deary, I.J.   +63 more
core   +1 more source

Transformation and CRISPR-Cas9-mediated homologous recombination in the fungus Rhizopus microsporus

STAR Protocols, 2022
Summary: Here, we describe a reliable approach for targeted DNA integrations in the genome of R. microsporus, one of the main causal agents of mucormycosis.
Carlos Lax, María Isabel Navarro-Mendoza, Carlos Pérez-Arques, Eusebio Navarro, Francisco Esteban Nicolás, Victoriano Garre   +5 more
doaj   +1 more source

Random-PE: an efficient integration of random sequences into mammalian genome by prime editing

Molecular Biomedicine, 2021
Prime editing (PE) enables efficiently targeted introduction of multiple types of small-sized genetic change without requiring double-strand breaks or donor templates.
Yaoge Jiao, Lifang Zhou, Rui Tao, Yanhong Wang, Yun Hu, Lurong Jiang, Li Li, Shaohua Yao   +7 more
doaj   +1 more source

Binary Genetic Cassettes for Selecting XNA‐Templated DNA Synthesis In Vivo [PDF]

Angewandte Chemie, 2013
sponsorship: GOA 10/013 IDO FWO Vlaanderen Genoscope (Genopole, Evry)(ATIGE, EA 4527, UPS 3509) FP7/2007-2013)/ERC Grant agreement n° ERC-2012- ADG_20120216/320683.XNA - xenobiotic nucleic acids.
Pezo, Valérie, Liu, Feng Wu, Abramov, Mikhail, Froeyen, Mathy, Herdewijn, Piet, Marlière, Philippe   +5 more
openaire   +4 more sources

A Search-based Approach for Generalizing and Refining Source Code Templates [PDF]

, 2015
Code templates are a convenient means to search and transform source code. However, such templates may still be difficult to specify, as they can produce too few or too many matches. To assist the users of our Ekeko/X program transformation tool, we have
Tim Molderez (99403), Coen De Roover (767434)   +1 more
core   +1 more source

Method for Rapid Analysis of Mutant RNA Polymerase Activity on Templates Containing Unnatural Nucleotides [PDF]

, 2021
Pairs of unnatural nucleotides are used to expand the genetic code and create artificial DNA or RNA templates. In general, an approach is used to engineer orthogonal systems capable of reading codons comprising artificial nucleotides; however, DNA and ...
Sabina Mukba, Tatiana Egorova, Peter Kolosov, Elena Alkalaeva, Alexey Shuvalov, Ekaterina Shuvalova   +5 more
core   +1 more source

Accurate and Rapid Genetic Tracing the Authenticity of Floral Originated Honey with the Molecular Lateral Flow Strip

Biosensors, 2022
Honey is a natural product and is heavily consumed for its well-known nutritional functions. Honeys with different floral origins possess distinctive flavors, tastes, functions and economic values.
Qian Wu, Qi Chen, Chao Yan, Jianguo Xu, Zhaoran Chen, Li Yao, Jianfeng Lu, Bangben Yao, Wei Chen   +8 more
doaj   +1 more source