Results 21 to 30 of about 219,031 (288)

The origins and physical roots of life’s dual – metabolic and genetic – nature [PDF]

open access: yes, 2017
This review paper aims at a better understanding of the origin and physical foundation of life’s dual – metabolic and genetic – nature. First, I give a concise ‘top-down’ survey of the origin of life, i.e., backwards in time from extant DNA/RNA/protein ...
De Tiège, Alexis
core   +2 more sources

Random-PE: an efficient integration of random sequences into mammalian genome by prime editing

open access: yesMolecular Biomedicine, 2021
Prime editing (PE) enables efficiently targeted introduction of multiple types of small-sized genetic change without requiring double-strand breaks or donor templates.
Yaoge Jiao   +7 more
doaj   +1 more source

Impact of template backbone heterogeneity on RNA polymerase II transcription. [PDF]

open access: yes, 2014
Variations in the sugar component (ribose or deoxyribose) and the nature of the phosphodiester linkage (3'-5' or 2'-5' orientation) have been a challenge for genetic information transfer from the very beginning of evolution.
Chong, Jenny   +5 more
core   +1 more source

Guided Genetic Algorithm: A New Template Concept

open access: yesProcedia Computer Science, 2015
AbstractGuided genetic algorithm and dynamic distributed double guided genetic algorithm are based on nature laws and by the Neo-Darwinism theory. These evolutionary approaches were very successful addressing Maximal Constraint Satisfaction Problems (Max-CSPs). Our work is inspired by a little mistake when dealing with in these two algorithms guidance.
Othman, Hajer BEN, Tagina, Moncef
openaire   +1 more source

Binary Genetic Cassettes for Selecting XNA‐Templated DNA Synthesis In Vivo [PDF]

open access: yesAngewandte Chemie, 2013
sponsorship: GOA 10/013 IDO FWO Vlaanderen Genoscope (Genopole, Evry)(ATIGE, EA 4527, UPS 3509) FP7/2007-2013)/ERC Grant agreement n° ERC-2012- ADG_20120216/320683.XNA - xenobiotic nucleic acids.
Pezo, Valérie   +5 more
openaire   +4 more sources

Accurate and Rapid Genetic Tracing the Authenticity of Floral Originated Honey with the Molecular Lateral Flow Strip

open access: yesBiosensors, 2022
Honey is a natural product and is heavily consumed for its well-known nutritional functions. Honeys with different floral origins possess distinctive flavors, tastes, functions and economic values.
Qian Wu   +8 more
doaj   +1 more source

Detection of minority variants within bovine respiratory syncytial virus populations using oligonucleotide-based microarrays [PDF]

open access: yes, 2008
Microarray technology, originally developed for highly parallel examination of gene expression is regarded as a potential tool in prognosis and diagnosis.
Baranowski, Eric   +4 more
core   +3 more sources

Construction of FWPV Chimaeric MVA

open access: yesBio-Protocol, 2015
Construction of chimaeric MVA is a useful tool with which to study gene function of related viruses. The protocol given here describes MVA chimaeras containing genes from Fowlpox virus (FWPV), although this can be applied to DNA derived from other ...
Karen Buttigieg, Michael Skinner
doaj   +1 more source

AD-SiamRPN: Anti-Deformation Object Tracking via an Improved Siamese Region Proposal Network on Hyperspectral Videos

open access: yesRemote Sensing, 2023
Object tracking using Hyperspectral Images (HSIs) obtains satisfactory result in distinguishing objects with similar colors. Yet, the tracking algorithm tends to fail when the target undergoes deformation.
Shiqing Wang   +4 more
doaj   +1 more source

Phylogeographic pattern of the striped snakehead, Channa striata in Sundaland: ancient river connectivity, geographical and anthropogenic signatures [corrected]. [PDF]

open access: yesPLoS ONE, 2012
A phylogeographic study of an economically important freshwater fish, the striped snakehead, Channa striata in Sundaland was carried out using data from mtDNA ND5 gene target to elucidate genetic patterning.
Min Pau Tan   +2 more
doaj   +1 more source

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