Results 31 to 40 of about 1,312,393 (235)

Effect of secretory leucocyte protease inhibitor on early tendon-to-bone healing after anterior cruciate ligament reconstruction in a rat model

open access: yesBone & Joint Research, 2022
Aims: To verify whether secretory leucocyte protease inhibitor (SLPI) can promote early tendon-to-bone healing after anterior cruciate ligament (ACL) reconstruction. Methods: In vitro: the mobility of the rat bone mesenchymal stem cells (BMSCs) treated
Yongmao Wu   +9 more
doaj   +1 more source

Bone Tendon Interface: A New Perspective on Rotator Cuff Healing

open access: yesOrthopaedic Journal of Sports Medicine, 2019
During rotator cuff repair surgery, fixation and incorporation of ruptured rotator cuff tendon into the bone is a major concern. Many studies have report the limitations in the healing potential of the bone-tendon interface. The structure and composition
Yucheng Sun MD, PhD   +2 more
doaj   +1 more source

Differences in placement of calcium phosphate-hybridized tendon grafts within the femoral bone tunnel during ACL reconstruction do not influence tendon-to-bone healing

open access: yesJournal of Orthopaedic Surgery and Research, 2017
Background Calcium phosphate (CaP)-hybridization of tendon grafts has been shown to improve tendon-to-bone healing. The purpose of this study was to clarify the influence of different tendon graft placement methods on tendon-to-bone healing using CaP ...
Hirotaka Mutsuzaki   +3 more
doaj   +1 more source

Exosomes derived from magnetically actuated bone mesenchymal stem cells promote tendon-bone healing through the miR-21-5p/SMAD7 pathway

open access: yesMaterials Today Bio, 2022
Graft healing after anterior cruciate ligament reconstruction (ACLR) involves slow biological processes, and various types of biological modulations have been explored to promote tendon-to-bone integration.
Xiang-Dong Wu   +8 more
doaj   +1 more source

A Systematic Review of Tissue Engineering Scaffold in Tendon Bone Healing in vivo

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Background: Tendon-bone healing is an important factor in determining the success of ligament reconstruction. With the development of biomaterials science, the tissue engineering scaffold plays an extremely important role in tendon-bone healing and bone ...
Zimu Mao   +23 more
doaj   +1 more source

Macrophage-Derived miRNA-Containing Exosomes Induce Peritendinous Fibrosis after Tendon Injury through the miR-21-5p/Smad7 Pathway

open access: yesMolecular Therapy: Nucleic Acids, 2019
Following tendon injury, the development of fibrotic healing response impairs tendon function and restricts tendon motion. Peritendinous tissue fibrosis poses a major clinical problem in hand surgery.
Haomin Cui   +5 more
doaj   +1 more source

Negative effect of zoledronic acid on tendon-to-bone healing: In vivo study of biomechanics and bone remodeling in a rat model

open access: yesActa Orthopaedica, 2018
Background and purpose — Outcome after ligament reconstruction or tendon repair depends on secure tendon-to-bone healing. Increased osteoclastic activity resulting in local bone loss may contribute to delayed healing of the tendon–bone interface.
Geir Aasmund Hjorthaug   +6 more
doaj   +1 more source

Dose-dependent new bone formation by extracorporeal shock wave application on the intact femur of rabbits [PDF]

open access: yes, 2008
Background: Whereas various molecular working mechanisms of shock waves have been demonstrated, no study has assessed in detail the influence of varying energy flux densities (EFD) on new bone formation in vivo. Methods: Thirty Chinchilla bastard rabbits
S. Milz   +15 more
core   +1 more source

The effects of age- and training-related changes in tendon stiffness on muscular force production and neuro-motor control during childhood [PDF]

open access: yes, 2011
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The research described in this thesis examined age- and strength training-related changes in Achilles tendon stiffness and plantarflexor force production in
Waugh, Charlotte
core   +6 more sources

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