Results 31 to 40 of about 7,183 (232)

Tenecteplase vs. alteplase for acute ischemic stroke: a systematic review

International Journal of Emergency Medicine, 2022
Introduction Thrombolysis for acute ischemic stroke (AIS) with alteplase is the currently approved therapy for patients who present within 4.5 h of symptom onset and meet criteria.
Neha Potla, Latha Ganti
doaj   +1 more source

Contribution of fibrinolysis to the physical component summary of the SF-36 after acute submassive pulmonary embolism [PDF]

, 2014
Acute pulmonary embolism (PE) can diminish patient quality of life (QoL). The objective was to test whether treatment with tenecteplase has an independent effect on a measurement that reflects QoL in patients with submassive PE.
Courtney, D. Mark, Diercks, Deborah B., Jones, Alan E., Kabrhel, Christopher, Kline, Jeffrey A., Klinger, James R., Nordenholz, Kristen E., Peitz, Geoffrey W., Rondina, Matthew T., Stewart, Lauren K.   +9 more
core   +1 more source

ST-Elevation myocardial infarction network: systematization in 205 cases reduced clinical events in the public health care system [PDF]

, 2012
BACKGROUND: The major cause of death in the city of São Paulo (SP) is cardiac events. At its periphery, in-hospital mortality in acute myocardial infarction is estimated to range between 15% and 20% due to difficulties inherent in large metropoles ...
Alves, Claudia Maria Rodrigues, Barbosa, Adriano H., Caluza, Ana Christina Vellozo, Carvalho, Antonio Carlos, Gonçalves, Iran, Matos, Lívia Nascimento de, Moreno, Antonio Célio C., Oliveira, Carlos Alexandre L. de, Tarkieltaub, Elcio, Zeefried, Claus   +9 more
core   +3 more sources

Tenecteplase in Pulmonary Embolism Patients: A Meta-Analysis and Systematic Review

Frontiers in Medicine, 2022
ObjectiveTo assess the efficacy and safety of tenecteplase in patients with pulmonary embolism (PE).MethodsWe completed the literature search on May 31, 2021 using PubMed, EMBASE and the Web of Science.
Zhu Zhang, Zhu Zhang, Zhu Zhang, Zhu Zhang, Linfeng Xi, Linfeng Xi, Linfeng Xi, Linfeng Xi, Linfeng Xi, Shuai Zhang, Shuai Zhang, Shuai Zhang, Shuai Zhang, Yunxia Zhang, Yunxia Zhang, Yunxia Zhang, Yunxia Zhang, Guohui Fan, Guohui Fan, Guohui Fan, Guohui Fan, Xincao Tao, Xincao Tao, Xincao Tao, Xincao Tao, Qian Gao, Qian Gao, Qian Gao, Qian Gao, Wanmu Xie, Wanmu Xie, Wanmu Xie, Wanmu Xie, Peiran Yang, Zhenguo Zhai, Zhenguo Zhai, Zhenguo Zhai, Zhenguo Zhai, Chen Wang, Chen Wang, Chen Wang, Chen Wang, Chen Wang, Chen Wang   +43 more
doaj   +1 more source

Evaluation of an Unfractioned Heparin Pharmacy Dosing Protocol for the Treatment of Venous Thromboembolism in Nonobese, Obese, and Severely Obese Patients [PDF]

, 2017
Background: Despite large interpatient variability in dose response, heparin is utilized for treatment of venous thromboembolism (VTE). Current data on the optimal heparin dosing in obese patients are conflicting. Objective: The objective was to evaluate
Breedlove, Emily Y., Hosch, Lindsey M., Knoderer, Chad A., Scono, Lauren E.   +3 more
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Predictors of in-hospital mortality in patients with ST-segment elevation myocardial infarction undergoing pharmacoinvasive treatment [PDF]

, 2013
OBJECTIVES: To identify predictors of in-hospital mortality in patients with acute myocardial infarction undergoing pharmacoinvasive treatment. METHODS: This was an observational, prospective study that included 398 patients admitted to a tertiary center
Alves, Claudia Maria Rodrigues, Amaral, Amaury, Barbosa, Adriano Henrique Pereira, Caixeta, Adriano, Carvalho, Antonio Carlos, Falcão, Felipe José de Andrade, Goncalves Junior, Iran, Perez, Fatima Cristina A., Sousa, Jose Marconi Almeida, Souza, José Augusto Marcondes de, Stefanini, Edson, Wilke, Luiz Carlos   +11 more
core   +5 more sources

Sex Differences in Outcomes After Tenecteplase for Minor Stroke: A Subanalysis of the TEMPO‐2 Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background In this subanalysis of the TEMPO‐2 (Tenecteplase Versus Standard of Care for Minor Ischaemic Stroke With Proven Occlusion) trial, a randomized clinical trial comparing tenecteplase and nonthrombolytic control in patients with minor stroke and ...
Amy Y. X. Yu, Shabnam Vatanpour, Aravind Ganesh, Thalia S. Field, Philip A. Barber, Philip M. C. Choi, Brian Buck, Timothy Kleinig, Carlos A. Molina, Bruce C. V. Campbell, Ramana Appireddy, Keith W. Muir, Michael D. Hill, Shelagh B. Coutts   +13 more
doaj   +1 more source

rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]

, 2014
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy, Eastwood, Jo-Ann, Gylys, Karen, Meyer, Dawn M, Zivin, Justin A   +4 more
core   +3 more sources

Pharmacological and Non-Pharmacological Recanalization Strategies in Acute Ischemic Stroke [PDF]

, 2011
According to the guidelines of the European Stroke Organization (ESO) and the American Stroke Association (ASA), acute stroke patients should be managed at stroke units that include well organized pre- and in-hospital care.
Anita Frendl, László Csiba
core   +3 more sources

Tenecteplase versus alteplase for acute ischaemic stroke in the elderly patients: a post hoc analysis of the TRACE-2 trial

Stroke and Vascular Neurology
Background The benefit–risk profile of tenecteplase in the elderly patients with acute ischaemic stroke (AIS) is uncertain. We sought to investigate the efficacy and safety of 0.25 mg/kg tenecteplase compared with alteplase for AIS patients aged ≥80 ...
Bruce C V Campbell, Yongjun Wang, Zixiao Li, Yunyun Xiong, Yuesong Pan, Lee H Schwamm, Shuya Li, Mengxing Wang, Na Wu, Liyuan Wang, Manjun Hao, Zhixin Cao, Chunmiao Duan, Shuangzhe Wu   +13 more
doaj   +1 more source