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Tenogenic differentiation of stem cells for tendon repair-what is the current evidence?

Journal of Tissue Engineering and Regenerative Medicine, 2011
Tendon/ligament injuries are very common in sports and other rigorous activities. Tendons regenerate and repair slowly and inefficiently in vivo after injury. The limited ability of tendon to self-repair and the general inefficiencies of current treatment regimes have hastened the motivation to develop tissue-engineering strategies for tissue repair ...
P P Y, Lui, Y F, Rui, M, Ni, K M, Chan
openaire   +2 more sources

Conditional tenomodulin overexpression favors tenogenic lineage differentiation of transgenic mouse derived cells

Gene, 2017
Tenomodulin (TNMD) is a type II transmembrane protein that is widely expressed in a variety of avascular connective tissues and fat tissue. Its function remains largely unknown except for a marker for mature tenocytes. This study reports the generation of tetracycline (Tet)-on driven conditional TNMD overexpressing mice and thus to provide a tool for ...
Yuan, Shi   +8 more
openaire   +2 more sources

[Strain-induced tenogenic differentiation of bone marrow mesenchymal stem cells].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2011
To study the possibility of bone marrow mesenchymal stem cells (BMSCs) differentiation into tenocytes (TCs) under strain stimulation by co-culture of BMSCs-small intestinal submucosa (SIS) composites in vitro.BMSCs were isolated by adherent culture from the bone marrow of 1-week-old SD rats.
Meixu, Liao   +5 more
openaire   +1 more source

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Frontiers in Cell and Developmental Biology, 2022
Chisa Shukunami   +2 more
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Development of a new in vitro tenogenic differentiation model

Journal of Tissue Science & Engineering, 2014
openaire   +1 more source

Enhanced tenogenic differentiation and tendon-like tissue formation by tenomodulin overexpression in murine mesenchymal stem cells

Journal of Tissue Engineering and Regenerative Medicine, 2017
Zhi-yong Zhang, Yilin Cao, Wei Liu
exaly  

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