Herbal Medicine Ninjin'yoeito in the Treatment of Sarcopenia and Frailty. [PDF]
Uto NS +8 more
europepmc +1 more source
Immunomodulating Phytochemicals: An Insight Into Their Potential Use in Cytokine Storm Situations. [PDF]
Alarabei AA +8 more
europepmc +1 more source
The critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network. [PDF]
Wang Y +9 more
europepmc +1 more source
Effects of natural extracts in cognitive function of healthy adults: a systematic review and network meta-analysis. [PDF]
Wang ZY, Deng YL, Zhou TY, Liu Y, Cao Y.
europepmc +1 more source
Plant natural products targeting NLRP3 inflammasome in Parkinson's disease: Molecular activation and regulation to therapeutics. [PDF]
Lu H +10 more
europepmc +1 more source
Tenuigenin protects cultured hippocampal neurons against methylglyoxal-induced neurotoxicity
Methylglyoxal is a metabolite of glucose. Since serum methylglyoxal level is increased in diabetic patients, methylglyoxal is implicated in diabetic complications such as cognitive impairment. This study aimed to evaluate the effects of tenuigenin, an active component of roots of Polygala tenuifolia Willdenow, on methylglyoxal-induced cell injury in a ...
Xiao-Bo Huang +2 more
exaly +4 more sources
Protective effects of tenuigenin on Staphylococcus aureus-induced pneumonia in mice
Pneumonia is the leading cause of death in infants and young children. Staphylococcus aureus (S.aureus) is one of the most important bacteria that leads to pneumonia. Tenuigenin (TGN), a major active component isolated from the root of the Chinese herb Polygala tenuifolia, has been known to have anti-inflammatory effect.
Lianyong Li
exaly +4 more sources
Neuroprotective effects of tenuigenin in a SH-SY5Y cell model with 6-OHDA-induced injury
Tenuigenin, an active component of Polygala tenuifolia root extracts, has been shown to provide antioxidative and anti-aging effects in Alzheimer's disease, as well as to promote proliferation and differentiation of neural progenitor cells. However, the effects of tenuigenin on Parkinson's disease remain unclear.
Fang Shi, Xiaomin Wang
exaly +4 more sources
Tenuigenin (TEN), a major active component of polygala tenuifolia root, has been reported to have a number of biological properties, such as anti-oxidative and anti-inflammatory activities. However, the protective effect of TEN on acute liver injury has not yet been reported.
Yanhong Liu
exaly +4 more sources

