Results 81 to 90 of about 26,590 (258)

Review of Teratogenic Effects of Leflunomide, Accutane, Thalidomide, Warfarin, Tetracycline, and Angiotensin-Converting Enzyme Inhibitors. [PDF]

Cureus, 2023
Abadie RB, Keller CL, Jones NT, Mayeux EL, Klapper RJ, Anderson L, Kaye AM, Ahmadzadeh S, Varrassi G, Shekoohi S, Kaye AD.   +10 more
europepmc   +1 more source

Exome Sequencing in Prenatally Diagnosed Isolated Neural Tube Defects: A Subtype‐Specific Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To explore potential genetic contributors across different subtypes of isolated neural tube defects (NTDs) ‐ acrania–exencephaly–anencephaly sequence (AEAS), spinal dysraphism, and encephalocele ‐ using exome sequencing (ES) in a prenatal cohort, with the goal of gaining insight into the molecular diversity underlying these distinct ...
Adi Botvinik, Vered Offen Glasner, Adi Reches, Hadas Miremberg, Karina Krajden Haratz, Tal brill, Liron Malki, Michal Rozenzwaig, Yuval Yaron, Michal Levy   +9 more
wiley   +1 more source

Sotalol Dose Optimization for Fetal Tachycardia: A Pregnancy Physiologically Based Pharmacokinetic Model Study

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To establish an optimized sotalol dosing strategy for fetal tachycardia using a pregnancy physiologically based pharmacokinetic (PBPK) model. Method A verified PBPK model was developed incorporating pregnancy‐induced physiological changes and placental transfer.
Hedwig van Hove, Joyce E. M. van der Heijden, Anne van Uden, Violette M. G. J. Gijsen, Rick Greupink, Saskia N. de Wildt, Joris van Drongelen   +6 more
wiley   +1 more source

Occupational Exposure to Inhalational Anesthetics and Teratogenic Effects: A Systematic Review. [PDF]

Healthcare (Basel), 2023
García-Álvarez JM, Escribano-Sánchez G, Osuna E, Molina-Rodríguez A, Díaz-Agea JL, García-Sánchez A.   +5 more
europepmc   +1 more source

Genetic correlations and clinical value of increased renal echogenicity in fetuses identified by prenatal ultrasonography

Precision Medical Sciences, EarlyView.
The corresponding images are as follows: enhanced fetal renal echo, enhanced fetal renal echo complicated with hydronephrosis, cardiac abnormality, chromosome microarray analysis: microdeletion of chromosome 17, whole‐exome sequencing: microdeletion of chromosome 17.
Haihong Liu, Yun Wu, Li Cao, Ting Zhou, LiJun Wu   +4 more
wiley   +1 more source

Cyclophilin A as a Pro-Inflammatory Factor Exhibits Embryotoxic and Teratogenic Effects during Fetal Organogenesis. [PDF]

Int J Mol Sci, 2023
Kalinina A, Semenova M, Bruter A, Varlamova E, Kubekina M, Pavlenko N, Silaeva Y, Deikin A, Antoshina E, Gorkova T, Trukhanova L, Salmina A, Novikova S, Voronkov D, Kazansky D, Khromykh L.   +15 more
europepmc   +1 more source

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

Cardiac disease in systemic sclerosis: Integrating pathobiology with clinical management

Rheumatology &Autoimmunity, EarlyView.
Abstract Systemic sclerosis (SSc) is a complex autoimmune disorder in which cardiovascular involvement remains a major determinant of morbidity and mortality. Cardiac injury in SSc results from the interplay of microvascular dysfunction, immune‐mediated inflammation, and progressive interstitial and replacement fibrosis, leading to myocardial disease ...
Henry Sutanto, Betty Rachma, Yuliasih
wiley   +1 more source

Chemical contaminants and environmental stressors induced teratogenic effect in aquatic ecosystem – A comprehensive review

Toxicology Reports
Aquatic environments, including marine and freshwater ecosystems, are vital for ecological balance and biodiversity. The rising global demand for aquaculture products necessitates increased production, with intensified aquaculture practices posing ...
S. Madesh, Sanjai Gopi, Avra Sau, Rajakrishnan Rajagopal, S. Karthick Raja Namasivayam, Jesu Arockiaraj   +5 more
doaj   +1 more source

Prenatal detection and outcome of major heart defects in a country with universal screening

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To evaluate the Danish prenatal screening program for major fetal congenital heart defects (mCHD), focusing on incidence, detection rates (DRs), pregnancy outcomes and postnatal mortality. Methods This was a 5‐year nationwide cohort study conducted from January 2018 to December 2022 in Denmark.
C. Vedel, J. Steensberg, O. B. Petersen, H. Andersen, M. Barbosa, M. Christiansen, V. Gjørup, A. N. Jensen, K. Munk, K. Nyborg, A. W. Olesen, F. Ravn, L. Sperling, H. G. H. Thyregod, N. Vejlstrup, C. K. Ekelund   +15 more
wiley   +1 more source