Results 1 to 10 of about 21,579 (291)

Mutagenicity and teratogenicity studies of vitacoxib in rats and mice

open access: yesToxicology Reports, 2018
Vitacoxib is a new drug candidate for treatment of inflammation, pain and fever as selective cyclooxygenase-2 inhibitors. In the current study, the mice sperm abnormality, mammalian erythrocyte micronucleus and in vivo chromosome aberration, and ...
Jianzhong Wang   +5 more
doaj   +2 more sources

Teratogenicity with olanzapine

open access: yesIndian Journal of Psychological Medicine, 2014
Olanzapine, a 2 nd generation antipsychotic, is in use in the clinical practice for nearly a decade and a half now. It is classified as a category C drug with very few reports of its toxic effects on the fetus.
Sathya Prakash, Rakesh Kumar Chadda
doaj   +4 more sources

Retinoids and teratogenicity [PDF]

open access: yesRomanian Journal of Pediatrics, 2021
For more than 30 years, retinoids have been used for acne treatment also their teratogenic effects are widely known. For any woman at a fertility age and under retinoid treatment, a contraception programme should be in place.
Lucian Pop   +4 more
doaj   +1 more source

Data on sodium tetraborate as a modulation of hypertrophic intracellular signals

open access: yesData in Brief, 2021
The present work benefits the use of sodium tetraborate to prevent and treat hypertrophic cardiac. The data obtained from the work could serve as a reference point to compare with data obtained in vivo studies with cardiac damage.
J. Roque-Jorge   +5 more
doaj   +1 more source

Teratogenicity of D-allulose

open access: yesToxicology Reports, 2022
The objective of this study was to evaluate whether D-allulose has teratogenic effects on rats. A prenatal developmental toxicity test was conducted in SD rats in compliance with modified OECD guidelines test number 414, prenatal developmental toxicity ...
Soonok Sa   +5 more
doaj   +1 more source

Knowledge, Attitude and Practice Regarding Medication use among Pregnant Women Attending Antenatal Clinic: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: Medication use during pregnancy is a major concern in India and poor awareness is driven by non scientific information sources. Primary care providers play a role in providing information on risk of teratogenic and folate deficiency birth ...
Rohan Sen   +3 more
doaj   +1 more source

A case of severe COVID-19 pneumonia in pregnancy managed with tofacitinib and review of literature [PDF]

open access: yesNew Indian Journal of OBGYN, 2023
The incidence of coronavirus disease (COVID-19) is increasing each day worldwide and the clinico-pharmacological dynamics of it is also changing with time. Pregnant women do also get infected though mostly mild to moderate in nature. To date, there is no
Jayanta Kumar Biswas , Rajat Chauhan
doaj   +1 more source

Hypertriglyceridemia‐induced pancreatitis after egg retrieval for in vitro fertilization and fenofibrate cessation

open access: yesClinical Case Reports, 2022
A 36‐year‐old woman with prior hypertriglyceridemia‐induced pancreatitis presented with a recurrence of pancreatitis after beginning in vitro fertilization (IVF). Her primary care physician had discontinued fenofibrate due to concerns for teratogenicity.
Tushaar V. Shrimanker   +2 more
doaj   +1 more source

Insights into Structural Modifications of Valproic Acid and Their Pharmacological Profile

open access: yesMolecules, 2021
Valproic acid (VPA) is a well-established anticonvulsant drug discovered serendipitously and marketed for the treatment of epilepsy, migraine, bipolar disorder and neuropathic pain.
Manish Kumar Mishra   +9 more
doaj   +1 more source

Toxicity Evaluation of the Naphthalen-2-yl 3,5-Dinitrobenzoate: A Drug Candidate for Alzheimer Disease

open access: yesFrontiers in Pharmacology, 2021
The presented study was designed to probe the toxicity potential of newly identified compound naphthalen-2-yl 3,5-dinitrobenzoate (SF1). Acute, subacute toxicity and teratogenicity studies were performed as per Organization of economic cooperation and ...
Fareeha Anwar   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy