Results 1 to 10 of about 21,579 (291)
Mutagenicity and teratogenicity studies of vitacoxib in rats and mice
Vitacoxib is a new drug candidate for treatment of inflammation, pain and fever as selective cyclooxygenase-2 inhibitors. In the current study, the mice sperm abnormality, mammalian erythrocyte micronucleus and in vivo chromosome aberration, and ...
Jianzhong Wang +5 more
doaj +2 more sources
Teratogenicity with olanzapine
Olanzapine, a 2 nd generation antipsychotic, is in use in the clinical practice for nearly a decade and a half now. It is classified as a category C drug with very few reports of its toxic effects on the fetus.
Sathya Prakash, Rakesh Kumar Chadda
doaj +4 more sources
Retinoids and teratogenicity [PDF]
For more than 30 years, retinoids have been used for acne treatment also their teratogenic effects are widely known. For any woman at a fertility age and under retinoid treatment, a contraception programme should be in place.
Lucian Pop +4 more
doaj +1 more source
Data on sodium tetraborate as a modulation of hypertrophic intracellular signals
The present work benefits the use of sodium tetraborate to prevent and treat hypertrophic cardiac. The data obtained from the work could serve as a reference point to compare with data obtained in vivo studies with cardiac damage.
J. Roque-Jorge +5 more
doaj +1 more source
The objective of this study was to evaluate whether D-allulose has teratogenic effects on rats. A prenatal developmental toxicity test was conducted in SD rats in compliance with modified OECD guidelines test number 414, prenatal developmental toxicity ...
Soonok Sa +5 more
doaj +1 more source
Knowledge, Attitude and Practice Regarding Medication use among Pregnant Women Attending Antenatal Clinic: A Cross-sectional Study [PDF]
Introduction: Medication use during pregnancy is a major concern in India and poor awareness is driven by non scientific information sources. Primary care providers play a role in providing information on risk of teratogenic and folate deficiency birth ...
Rohan Sen +3 more
doaj +1 more source
A case of severe COVID-19 pneumonia in pregnancy managed with tofacitinib and review of literature [PDF]
The incidence of coronavirus disease (COVID-19) is increasing each day worldwide and the clinico-pharmacological dynamics of it is also changing with time. Pregnant women do also get infected though mostly mild to moderate in nature. To date, there is no
Jayanta Kumar Biswas , Rajat Chauhan
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A 36‐year‐old woman with prior hypertriglyceridemia‐induced pancreatitis presented with a recurrence of pancreatitis after beginning in vitro fertilization (IVF). Her primary care physician had discontinued fenofibrate due to concerns for teratogenicity.
Tushaar V. Shrimanker +2 more
doaj +1 more source
Insights into Structural Modifications of Valproic Acid and Their Pharmacological Profile
Valproic acid (VPA) is a well-established anticonvulsant drug discovered serendipitously and marketed for the treatment of epilepsy, migraine, bipolar disorder and neuropathic pain.
Manish Kumar Mishra +9 more
doaj +1 more source
The presented study was designed to probe the toxicity potential of newly identified compound naphthalen-2-yl 3,5-dinitrobenzoate (SF1). Acute, subacute toxicity and teratogenicity studies were performed as per Organization of economic cooperation and ...
Fareeha Anwar +9 more
doaj +1 more source

