Results 31 to 40 of about 48,551 (323)

A case of severe COVID-19 pneumonia in pregnancy managed with tofacitinib and review of literature [PDF]

open access: yesNew Indian Journal of OBGYN, 2023
The incidence of coronavirus disease (COVID-19) is increasing each day worldwide and the clinico-pharmacological dynamics of it is also changing with time. Pregnant women do also get infected though mostly mild to moderate in nature. To date, there is no
Jayanta Kumar Biswas , Rajat Chauhan
doaj   +1 more source

Preventing teratogenicity in women with epilepsy [PDF]

open access: yes, 2022
Over the last 50 years there has been a significant increase in our understanding of the issues faced by women with epilepsy, in both planning and undertaking pregnancy.
Smith, Phil E. M.   +2 more
core   +1 more source

Hypertriglyceridemia‐induced pancreatitis after egg retrieval for in vitro fertilization and fenofibrate cessation

open access: yesClinical Case Reports, 2022
A 36‐year‐old woman with prior hypertriglyceridemia‐induced pancreatitis presented with a recurrence of pancreatitis after beginning in vitro fertilization (IVF). Her primary care physician had discontinued fenofibrate due to concerns for teratogenicity.
Tushaar V. Shrimanker   +2 more
doaj   +1 more source

Insights into Structural Modifications of Valproic Acid and Their Pharmacological Profile

open access: yesMolecules, 2021
Valproic acid (VPA) is a well-established anticonvulsant drug discovered serendipitously and marketed for the treatment of epilepsy, migraine, bipolar disorder and neuropathic pain.
Manish Kumar Mishra   +9 more
doaj   +1 more source

Recent advances in the molecular mechanism of thalidomide teratogenicity.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020
Thalidomide was first marketed in 1957 but soon withdrawn because of its notorious teratogenicity. Studies on the mechanism of action of thalidomide revealed the pleiotropic properties of this class of drugs, including their anti-inflammatory ...
Shaobing Gao   +3 more
semanticscholar   +1 more source

Morphometric analysis of developing zebrafish embryos allows predicting teratogenicity modes of action in higher vertebrates.

open access: yesReproductive Toxicology, 2020
The early identification of teratogens in humans and animals is mandatory for drug discovery and development. Zebrafish has emerged as an alternative model to traditional preclinical models for predicting teratogenicity and other potential chemical ...
S. Jarque   +6 more
semanticscholar   +1 more source

apchalla/teratogenicity-qsar: teratogenicity-qsar [PDF]

open access: yes, 2019
This release contains supplemental code and data files for the publication "Machine learning on drug-specific data to predict small molecule teratogenicity" by Challa et ...
Anup P. Challa
core   +1 more source

Toxicity Evaluation of the Naphthalen-2-yl 3,5-Dinitrobenzoate: A Drug Candidate for Alzheimer Disease

open access: yesFrontiers in Pharmacology, 2021
The presented study was designed to probe the toxicity potential of newly identified compound naphthalen-2-yl 3,5-dinitrobenzoate (SF1). Acute, subacute toxicity and teratogenicity studies were performed as per Organization of economic cooperation and ...
Fareeha Anwar   +9 more
doaj   +1 more source

Embryotoxicity and Teratogenicity of Steroidal Saponin Isolated from Ophiopholis mirabilis [PDF]

open access: yes, 2023
Benthic invertebrates produce secondary metabolites that serve as defenses against consumers and promote their fitness. To explore the chemical defense in marine benthic echinoderms, the chemical constituents of Ophiopholis mirabilis were investigated. A
Yanfang Liu   +11 more
core   +1 more source

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