Results 41 to 50 of about 21,579 (291)
Teratogenicity and Teratogenic Factors
MOJ Anatomy & Physiology, 2017 Teratology is the science that investigates the congenital malformations and their causes Intrauterine exposure to a toxicant particularly in early pregnancy induces embryonic and fetal changes ranging from none up to malformations and stillbirths The teratogenic agents include some viral spirochetal and protozoal infections physical agents as ionizing
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Termination of Pregnancy Following Periconception Isotretinoin Exposure in South Korea
Clinical and Experimental Obstetrics & GynecologyBackground: Despite South Korea’s Ministry of Food and Drug Safety (MFDS) risk management program (RMP) since June 2019, isotretinoin prescriptions have surged 2.5 times from 0.39 million in 2017 to 0.97 million in 2021.
Young-Rae Lee +7 more
doaj +1 more source
Benzene histotoxic and teratogenic Effects in exposed Mice
Kufa Journal for Veterinary Medical Sciences, 2017 Throughout the last two decades, benzene was a prominent source of an occupational and environmental pollution in Iraq. Especially from direct contact with private electric generators which were installed closer to homes or even inside every home in ...
Hussamadin kadhim +4 more
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Regulating teratogenicity as a health risk
, 1991 The development of scientific knowledge and regulatory policy with respect to teratogenicity is reviewed. The current debate on the definition of teratogenicity and on perceived risks, as illustrated by the Dutch Health Council report on teratogenicity ...
Gilden, Nanda, Bodewitz, Henk
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FEBS Open Bio, EarlyView.The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Reproductive‐age women with systemic autoimmune and rheumatic diseases (SARDs) have unique information needs related to their SARDs and reproductive health. We sought to understand their use of and receptivity to current and hypothetical generative artificial intelligence (AI) tools for health information‐seeking. Methods We conducted a cross‐
Mariam Arif +5 more
wiley +1 more source
Advanced Science, EarlyView.Amcinonide (AMC), the FDA‐approved corticosteroid, was identified as a repurposed agent for radiation‐resistant colorectal cancer. AMC suppresses radiation‐induced epithelial–mesenchymal transition, migration, and invasion via the circRNF10/miR‐296‐5p/Snail axis.
Hyun Jeong Seok +4 more
wiley +1 more source
Acta Scientiarum: Biological Sciences, 2015 Teratogenicity and developmental abnormalities in the offspring of female rats that ingested ethanol extract of Neem plants during pregnancy and lactation period were assessed. Twenty-four female Wistar rats were randomly distributed in control group and
Vanessa Carla Lima da Silva +5 more
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American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto +5 more
wiley +1 more source
Esco2 and cohesin regulate CRL4 ubiquitin ligase ddb1 expression and thalidomide teratogenicity
, 2022 Cornelia de Lange syndrome (CdLS) and Roberts syndrome (RBS) are severe developmental maladies that arise from mutation of cohesin (including SMC3, CdLS) and ESCO2 (RBS).
Elise D. Thren (11912930) +3 more
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