Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells [PDF]
Cell Death Discovery, 2023 Summary Animal studies for embryotoxicity evaluation of potential therapeutics and environmental factors are complex, costly, and time-consuming. Often, studies are not of human relevance because of species differences.
Anna Cherianidou +11 more
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A standardized human embryoid body platform for the detection and analysis of teratogens. [PDF]
PLoS ONE, 2017 Teratogens are compounds that can induce birth defects upon exposure of the developing fetus. To date, most teratogen studies utilize pregnant rodents to determine compound teratogenicity in vivo.
Anthony Flamier +2 more
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Teratogens: a public health issue – a Brazilian overview
Genetics and Molecular Biology, 2017 Congenital anomalies are already the second cause of infant mortality in Brazil, as in many other middle-income countries in Latin America. Birth defects are a result of both genetic and environmental factors, but a multifactorial etiology has been more ...
Thiago Mazzu-Nascimento +6 more
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Disruption of normal body axis formation after teratogen exposure [PDF]
, 2007 International audienceUrban transport plans in France (UTPs) aim to develop mobility for everyone and to find a balance between cars, public transport and other transport modes, this in order to favour sustainable mobility.
Ahlgren, Sara C., Loucks, Evyn J.
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High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation [PDF]
Cells, 2022 Human-relevant tests to predict developmental toxicity are urgently needed. A currently intensively studied approach makes use of differentiating human stem cells to measure chemically-induced deviations of the normal developmental program, as in a ...
Florian Seidel +18 more
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Evaluation of the knowledge and practices of pregnant Yemeni Women regarding teratogens
, 2017 Purpose: To investigate the knowledge and practice of pregnant women with regards to teratogens. Methods: A month-long cross-sectional study was carried out among 150 pregnant women selected from four Motherhood and Child Healthcare Centers (MCHCs) in ...
Saeed Alfadly +9 more
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Experiences of sexual and reproductive health screening and counseling in the clinical setting among adolescents and young adults with rheumatic disease [PDF]
Pediatric Rheumatology Online JournalBackground Our objective was to describe differences among adolescents and young adults (AYAs) with rheumatic disease using teratogens compared to non-users in receipt of sexual and reproductive health (SRH) counseling, teratogenicity knowledge ...
Brittany Huynh +2 more
doaj +2 more sources
Journal of Animal Science, 1984 Many compounds synthesized by plants are known to be teratogenic in laboratory animals, but only a few have been shown by feeding trials to produce terata in livestock. Studies of plant teratogens affecting livestock have not moved forward in a systematic nor rapid way because of the logistical problems connected with such experiments in large animals.
R. Keeler
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Ocular teratogens: old acquaintances and new dangers [PDF]
Eye, 2009 Anupama Tandon, Alan Mulvihill
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Teratogens and Congenital Heart Disease [PDF]
, 2015 Tara A. Lynch, David E. Abel
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