Results 21 to 30 of about 12,518 (290)
Genetic Susceptibility to Drug Teratogenicity: A Systematic Literature Review
Frontiers in Genetics, 2021 Since the 1960s, drugs have been known to cause teratogenic effects in humans. Such teratogenicity has been postulated to be influenced by genetics. The aim of this review was to provide an overview of the current knowledge on genetic susceptibility to ...
Julia do Amaral Gomes +22 more
doaj +1 more source
Pregnancy and neonatal outcomes after periconceptional exposure to isotretinoin in Koreans [PDF]
Obstetrics & Gynecology Science, 2022 Objective Isotretinoin should not be used during pregnancy because of the risk of birth defects. Most pregnant women exposed to isotretinoin choose voluntary pregnancy termination due to concerns about birth defects.
Eun-Hwan Cha +9 more
doaj +1 more source
From the Farm to the Lab: How Chicken Embryos Contribute to the Field of Teratology
Frontiers in Genetics, 2021 Congenital anomalies and its causes, particularly, by external factors are the aim of the field called teratology. The external factors studied by teratology are known as teratogens and can be biological or environmental factors for example, chemicals ...
Gabriela Elis Wachholz +10 more
doaj +1 more source
Oral Clefts with Associated Anomalies: Findings in the Hungarian Congenital Abnormality Registry [PDF]
, 2005 BACKGROUND: Over the years, great efforts have been made to record the frequency of orofacial clefts in different populations. However, very few studies were able to account for the etiological and phenotypic heterogeneity of these conditions. Thus, data
Czeizel, Andrew E. +2 more
core +3 more sources
F1000Research, 2016 Background: Acute high dose exposure to teratogenic chemicals alters the proper development of an embryo leading to infertility, impaired fecundity, and few viable offspring.
Alexis Killeen +1 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 Congenital Zika Syndrome (CZS) occurs in up to 42% of individuals exposed to ZIKV prenatally. Deregulation in gene expression and protein levels of components of the p53 signaling pathway, such as p53 and MDM2, due to ZIKV infection has been reported ...
Julia A. Gomes +26 more
doaj +1 more source
Arterial dysgenesis and limb defects : Clinical and experimental examples [PDF]
, 2017 Acknowledgements This article is dedicated to Dr David S. Packard Jr. With thanks to Dr John DeSesso, Dr Lewis B. Holmes, Dr Mark Levinsohn, Dr David S.
Hootnick, David R., Vargesson, Neil
core +1 more source
Journal of Family Medicine and Primary Care, 2020 Aim: To investigate the knowledge of Saudi women regarding the teratogenic effects of environmental agents such as fever, some chronic conditions and medications and its association with certain socio-demographic factors.
Wejdan Alhamdan +7 more
doaj +1 more source
Teratogenic Effects of Diatom Metabolites on Sea Urchin Paracentrotus lividus Embryos
Marine Drugs, 2010 The diatom-derived polyunsaturated aldehydes (PUAs), 2-trans,4-trans-decadienal, 2-trans,4-trans-octadienal, 2-trans,4-trans,7-octatrienal, 2-trans,4-trans-heptadienal, as well as tridecanal were tested on early and later larval development in the sea ...
Giovanna Romano +2 more
doaj +1 more source
Expert consensus on neurodevelopmental outcomes in pregnancy pharmacovigilance studies
Frontiers in Pharmacology, 2023 Background: Exposure in utero to certain medications can disrupt processes of fetal development, including brain development, leading to a continuum of neurodevelopmental difficulties.
R. L. Bromley +31 more
doaj +1 more source