Results 41 to 50 of about 12,518 (290)
Horizonte Médico, 2018 Due to ethical reasons, very scarce clinical assays have been conducted and published. This situation has resulted in the exaggeration of drug risk during pregnancy, thus limiting its reasonable use for chronic diseases in pregnant women.
José Sandoval Paredes +1 more
doaj +1 more source
Exposição à teratógenos e anormalidades oculares congênitas em pacientes brasileiros portadores da sequência de Möbius [PDF]
, 2014 Purpose: To assess the sociodemographic profiles, teratogen exposures, and ocular congenital abnormalities in Brazilian patients with Möbius sequence. Method: Forty-four patients were recruited from the Brazilian Möbius Sequence Society.
Brandt, Carlos Teixeira +11 more
core +2 more sources
Cells, 2022 Human-relevant tests to predict developmental toxicity are urgently needed. A currently intensively studied approach makes use of differentiating human stem cells to measure chemically-induced deviations of the normal developmental program, as in a ...
Florian Seidel +18 more
doaj +1 more source
CAQ Corner: Basic concepts of transplant immunology
, 2022 Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley +1 more source
Risk factors and demographics for microtia in South America: a case-control analysis [PDF]
, 2013 BACKGROUND: The etiopathogenesis of microtia is still unknown in the majority of the cases, particularly for individuals presenting with isolated microtia.
Castilla, Eduardo Enrique +4 more
core +1 more source
Medication use in pregnancy: a cross-sectional, multinational web-based study [PDF]
, 2014 Objectives: Intercountry comparability between studies on medication use in pregnancy is difficult due to dissimilarities in study design and methodology. his study aimed to examine patterns and factors associated with medications use in pregnancy from a
Bjornsdottir, I. +17 more
core +5 more sources
A method for human teratogen detection by geometrically confined cell differentiation and migration [PDF]
, 2014 Unintended exposure to teratogenic compounds can lead to various birth defects; however current animal-based testing is limited by time, cost and high inter-species variability.
Toh, Yi-Chin +3 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
Teratogens: a public health issue – a Brazilian overview
Genetics and Molecular Biology, 2017 Congenital anomalies are already the second cause of infant mortality in Brazil, as in many other middle-income countries in Latin America. Birth defects are a result of both genetic and environmental factors, but a multifactorial etiology has been more ...
Thiago Mazzu-Nascimento +6 more
doaj +1 more source
Identifying signals of potentially harmful medications in pregnancy: use of the double false discovery rate method to adjust for multiple testing. [PDF]
, 2018 AIMS: Surveillance of medication use in pregnancy is essential to identify associations between first trimester medications and congenital anomalies (CAs). Medications in the same Anatomical Therapeutic Chemical classes may have similar effects. We aimed
Cavadino, A +2 more
core +2 more sources