Results 31 to 40 of about 2,627 (175)

Testicular Biopsies in Adolescent and Adult Andrological Patients: The EAA Clinical Guidelines

Andrology, EarlyView.
ABSTRACT Background Histological evaluation of testicular tissue is central to the assessment of infertile men, particularly those at an increased risk of testicular germ cell tumors (TGCT). Traditionally, testicular biopsies have been used primarily for diagnostic purposes, such as the detection of germ cell neoplasia in situ (GCNIS). With advances in
Lise Aksglaede, George Kanakis, Ewa Rajpert‐De Meyts, Davor Jezek, Ferran Algaba, Gert Dohle, Jolanta Slowikowska‐Hilczer, Sabine Kliesch, Hermann M. Behre, Csilla Krausz, Dimitrios G. Goulis, Niels Jørgensen   +11 more
wiley   +1 more source

Controlled cooling versus rapid freezing of teratozoospermic semen samples: Impact on sperm chromatin integrity

Journal of Human Reproductive Sciences, 2011
Aim: The present study evaluates the impact of controlled slow cooling and rapid freezing techniques on the sperm chromatin integrity in teratozoospermic and normozoospermic samples.
Shivananda N Kalludi, Guruprasad Kalthur, Susan Benjamin, Pratap Kumar, Satish Kumar Adiga   +4 more
doaj   +1 more source

Description of the semen quality from men treated in an assisted reproduction center in Guayaquil, Ecuador

Revista Peruana de Medicina Experimental y Salud Pública, 2020
In order to characterize the quality of semen from men in an assisted reproduction center in the city of Guayaquil (Ecuador), 204 semen samples were collected from patients with fertility disorders aged 20 to 57 years, who were admitted between May 2017 ...
Gabriel Morey-León, Tatiana Puga-Torres, Xavier Blum-Rojas, Manuel González-González, Alexandra Narváez-Sarasti, Nancy Sorroza-Rojas   +5 more
doaj   +1 more source

Analyzing the Differential Impact of Semen Preparation Methods on the Outcomes of Assisted Reproductive Techniques

Biomedicines, 2023
Sperm separation plays a critical role in assisted reproductive technology. Based on migration, density gradient centrifugation and filtration, a properly selected sperm could help in increasing assisted reproductive outcomes in teratozoospermia (TZs ...
Riffat Bibi, Sarwat Jahan, Tayyaba Afsar, Ali Almajwal, Mohamad Eid Hammadeh, Houda Amor, Ali Abusharha, Suhail Razak   +7 more
doaj   +1 more source

Y chromosome microdeletions: are they implicated in teratozoospermia? [PDF]

Human Reproduction, 2005
Y chromosome microdeletions are known to impair spermatogenesis. Screenings for these microdeletions are performed mostly in patients with sperm count abnormalities.We have screened the Y chromosome of 80 infertile patients with sperm morphological abnormalities.
Ali, Hellani, Saad, Al-Hassan, Adel, Al-Duraihim, Serdar, Coskun   +3 more
openaire   +2 more sources

Improving ARTs: Microfluidics as a Tool for Sperm Selection

Andrology, EarlyView.
ABSTRACT Sperm selection is a critical step in assisted reproductive technology (ART), as sperm quality directly influences embryo quality. In vivo, the female reproductive tract imposes several physical and physiological barriers that favors only the most optimal spermatozoa reaching the fertilization site.
A. Pérez‐Gómez, A. Urriés, J. L. de Pablo, L. Serrano‐Ramón, S. Sanchez, R. Herrer, J. M. Morrell, C. Malo   +7 more
wiley   +1 more source

Relationship Between Sperm Parameters and Indices of Chromatin Condensation and DNA Fragmentation in Semen

Biology
Infertility is a major health problem affecting about 15% of couples worldwide. Male etiology is found in almost one-third of cases. This study identified the nature of the relationship between sperm DNA fragmentation (SDF), sperm chromatin condensation (
Othmane Adli, Noureddine Louanjli, Rachid Aboutaieb   +2 more
doaj   +1 more source

Obesity Is an Independent Risk Factor for Oligozoospermia, With Co‐Existing Hyperglycemia Exacerbating Risks of Asthenozoospermia and Elevated Sperm DNA Fragmentation

Andrology, EarlyView.
ABSTRACT Background Metabolic health plays a critical role in maintaining male fertility and may influence offspring health. Therefore, it is necessary to incorporate metabolic indicators into the clinical assessment of male fertility. However, the relationships between different metabolic abnormalities and semen quality remain incompletely understood.
Rubing Hu, Haijiao Zou, Qiaodan Li, Weihong Fan, Jian Xu   +4 more
wiley   +1 more source

Teratozoospermia in mice lacking the transition protein 2 (Tnp2) [PDF]

Molecular Human Reproduction, 2001
It is believed that the transition proteins (Tnp1 and Tnp2) participate in the removal of the nucleohistones and in the initial condensation of the spermatid nucleus. Later in spermatogenesis, Tnp1 and Tnp2 are replaced by the protamines 1 and 2.
Adham, Ibrahim M., Nayernia, K., Burkhardt-Gottges, E., Topaloglu, O., Dixkens, C., Holstein, A. F., Engle, W.   +6 more
openaire   +3 more sources

Biallelic Truncating Variant in LRGUK Is Associated With Severe Multiple Morphological Abnormalities of the Sperm Flagella and Sperm Nuclear Defects in Humans

Clinical Genetics, EarlyView.
A homozygous truncating variant in LRGUK results in loss of the LRGUK protein and causes multiple morphological abnormalities of the flagella (MMAF), disrupted axonemal architecture, central pair defects, abnormal chromatin organization, and severe male infertility, establishing LRGUK as a novel human infertility gene.
Wiâme Mokkedem, Zeina Wehbe, Anne‐Laure Barbotin, Angèle Boursier, Célia Tebbakh, Nicolas Thierry‐Mieg, Marie Bidart, Antonella Migliaccio, Rosanna Chianese, Christophe Arnoult, Raoudha Zouari, Zine‐Eddine Kherraf, Pierre F. Ray, Guillaume Martinez, Charles Coutton   +14 more
wiley   +1 more source