Results 71 to 80 of about 4,887 (219)

Deciphering mRNA Translation During Sperm Capacitation: A New Frontier in Fertility Research

Molecular Reproduction and Development, Volume 93, Issue 2, February 2026.
ABSTRACT Male infertility accounts for approximately 50% of infertility cases, with nearly 30% remaining unexplained after standard evaluations. This highlights the need for a better understanding of sperm function to advance diagnostic and therapeutic strategies. Sperm were long considered translationally quiescent; however, emerging evidence suggests
Saurabh Tiwari, Nehal Thakor, Jacob Thundathil   +2 more
wiley   +1 more source

Lifestyle implications of the paradox and management of oxidative stress in sperm

The Journal of Physiology, Volume 604, Issue 3, Page 1028-1044, 1 February 2026.
Abstract figure legend Lifestyle factors influencing male fertility. Schematic overview of lifestyle factors with beneficial (left) and detrimental (right) effects on male fertility. A balanced diet, regular moderate physical activity and stress management strategies support sperm function and redox homeostasis.
Giuseppe T. Patané, Ruben J. Moreira, Annamaria Russo, Maria L. Pereira, Pedro F. Oliveira, Davide Barreca, Marco G. Alves   +6 more
wiley   +1 more source

Comparative Evaluation of Two Microfluidic Sperm Sorting Devices: Laboratory Assessment of Sperm Quality and Retrospective Analysis of Embryological Outcomes Following Intracytoplasmic Sperm Injection

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose Density gradient centrifugation (DGC) enriches motile sperm but may increase sperm DNA fragmentation (SDF), whereas microfluidic sperm sorting devices, such as ZyMōt and CA0, enable centrifugation‐free selection with lower SDF. Direct comparisons are limited, and their relative clinical efficacy remains unclear.
Ryota Tachibana, Hiroki Takeuchi, Miyu Yotsutani, Mikiko Nishioka, Erina Takayama, Eiji Kondo   +5 more
wiley   +1 more source

Degradación enzimática de TRH y análogos en semen humano. Posible función en la fertilidad [PDF]

, 2001
Recientemente se ha descrito la presencia en semen humano de un péptido similar a la hormona liberadora de tirotropina (TRH) directamente implicado en la fertilidad, habiéndose denominado FPP (péptido promotor de la fertilidad).
FERNÁNDEZ OSORIO, David, GIL GOIKOURIA, Javier, IRAZUSTA ASTIAZARAN, Jon, LARRINAGA ENBEITA, Gorka, MUJIKA GARAY, Juan, OCHOA, Carmen   +5 more
core  

Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]

, 2011
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
El Hajj, N., Gromoll, J., Haaf, T., Hahn, T., Schneider, E., Schorsch, M., Tresch, A., Zechner, Ulrich   +7 more
core   +1 more source

Long‐Read Sequencing of CAH and ADPKD Provides Novel Insights Into the Genetic Diagnosis of Male Infertility

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose This study aimed to evaluate the utility of long‐read sequencing (LRS) in identifying variants of congenital adrenal hyperplasia (CAH) and autosomal dominant polycystic kidney disease (ADPKD) in infertile men, which may help further clarify genetic diagnosis and support genetic counseling and reproductive management. Methods A total of
Xiao Li, Chang Liu, Wen Liu, Xianlong Wang, Jiaolong Liu, Feifei Cai, Shaoming Lu   +6 more
wiley   +1 more source

[Molecular basis of teratozoospermia].

Ginekologia polska, 2001
Teratozoospermia is considered to be one of the most challenging phenomenon of male infertility at proper diagnosis and therapy. In this report, we described controversies regarding current methods of evaluation of sperm morphology and predictive value of this sperm feature in connection to assisted reproduction and/or functional sperm tests in vitro ...
M, Kurpisz, M, Szczygieł
openaire   +1 more source

Can intracytoplasmic morphologically selected spermatozoa injection be used as first choice of treatment for severe male factor infertility patients?

Journal of Human Reproductive Sciences, 2018
Aim: This study was carried out to assess the outcome of the intracytoplasmic morphologically selected sperm injection (IMSI) technique compared with the previous failed intracytoplasmic sperm injection (ICSI) attempts in oligoasthenoteratozoospermia ...
Geeta Goswami, Meeta Sharma, Deepika Jugga, Devi M Gouri   +3 more
doaj   +1 more source

Nuclear morphologies: their diversity and functional relevance. [PDF]

, 2017
Studies of chromosome and genome biology often focus on condensed chromatin in the form of chromosomes and neglect the non-dividing cells. Even when interphase nuclei are considered, they are often then treated as interchangeable round objects.

core   +2 more sources

Exploratory Multiomics Profiling Reveals ACTN4‐Centric Cytoskeletal Failure and Environmental Arsenic Association in Morphologically Defined Oligoasthenoteratospermia Subtypes

Andrologia, Volume 2026, Issue 1, 2026.
Background Oligoasthenoteratospermia (OAT) represents a major cause of male infertility. The molecular mechanisms underlying sperm morphological defects, particularly their potential interplay with environmental exposure‐associated molecular alterations, remain poorly understood and warrant exploratory investigation.
Shuting Cheng, Xin Zhuo, Jinzhan Yao, Mengyue Feng, Yuan Yu, Xiaohui Jiang, Xin Liang, Xudong Shan, Zhou Jiang, Harleen Khatra   +9 more
wiley   +1 more source