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Background: Dermatophytosis is a major health problem in developing countries, with their increase in resistance patterns toward various antifungals being the main reason for concern.
Suraj Pawar, Ashish R Deshmukh
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Dermatophyte infections represent an important public health concern, affecting up to 25% of the world’s population. Trichophyton rubrum and T. mentagrophytes are the predominant dermatophytes in cutaneous infections, with a prevalence accounting for 70%
A. Trifan+12 more
semanticscholar +1 more source
TREATMENT OF DERMATOPHYTE ONYCHOMYCOSIS WITH TERBINAFINE (LAMISIL) PULSE THERAPY [PDF]
Terbinafine is the most active currently available antidermatophyte agent with fungicidal action. The aim of the present study was to assess the efficacy of terbinafine pulse therapy in the treatment of dermatophyte nail infections.
Sonia Valkova
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Introduction Trichophyton mentagrophytes and T. interdigitale are important causative agents of superficial mycoses, demonstrating emergent antifungal drug resistance.
S. Taghipour+10 more
semanticscholar +1 more source
Terbinafine versus itraconazole: a long-term, randomized, double-blind, clinical trial in chronic pulmonary aspergillosis. A pilote study [PDF]
Background: The frequency of pulmonary aspergillosis has been increasing for decades. Standard oral treatment is associated with tolerability problems and interactions with commonly used medications.
Gianfranco Schiraldi+6 more
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Terbinafine is used as the first-line therapy for dermatophytosis, but the incidence of terbinafine resistance is increasing. A combination of terbinafine with itraconazole was tested using the checkerboard method based on the EUCAST methodology for ...
A. Bidaud+3 more
semanticscholar +1 more source
Therapeutic effects of a novel DA5505 formulation on a guinea pig model of tinea pedis
Background/Objective: Tinea pedis, a superficial mycosal infection affecting the soles and toe webs of feet, is generally treated with terbinafine. However, the main problem with available marketed formulations is their inability to deliver terbinafine ...
Raj Kumar Thapa+6 more
doaj +1 more source
The article entitled “Aplastic Anemia Associated with Oral Terbinafine: A Case Report and Review of the Literature”, written by Kantarcioglu et al. and published in a recent issue of your journal, was quite interesting [1]. Here we would like to emphasize some relevant points.
openaire +3 more sources
We use here two genomic screens in an attempt to understand the mode of action and resistance mechanism of terbinafine, an antifungal contemplated as a potential drug against the parasite Leishmania.
Jade-Éva Potvin+5 more
doaj
ABSTRACT We hereby present the case of a patient with tinea incognita, who had received treatment with glucocorticosteroids and antibiotics for several months. Further diagnostic testing identified Trichophyton indotineae as the pathogen causing tinea corporis and cruris. The Erg1 gene encoding squalene epoxidase showed wild‐type information; therefore,
Deborah M. Gregersen+4 more
wiley +1 more source