Results 41 to 50 of about 9,832 (188)

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Cytoplasmic fungal lipases release fungicides from ultra-deformable vesicular drug carriers. [PDF]

PLoS ONE, 2012
The Transfersome® is a lipid vesicle that contains membrane softeners, such as Tween 80, to make it ultra-deformable. This feature makes the Transfersome® an efficient carrier for delivery of therapeutic drugs across the skin barrier.
Gero Steinberg
doaj   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta, Tong Wang, Susmita, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +5 more
wiley   +1 more source

Comparison Of Therapeutic Effectiveness With Clotrimazole 1% Cream With Terbinafine 1% Cream In Patients Therapy Given To Tinea Corporis And Tinea Cruris In Kashan

پیاورد سلامت, 2015
Background and Aim: Dermatophytosis is a skin infection without involving of hair, and in fact, Tinea cruris is a form of body Dermatophytosis. For treatment of these two diseases, topical azole or Alylamines are usually used.
Rezvan Talaee, Mohammad Dakhili, Mohammad Ali Asadi, Seyed Hamed Sharif Arani, Hossein Akbari, Afshin Salehi   +5 more
doaj   +2 more sources

Hyalohyphomycotic chronic rhinosinusitis caused by Microascus cirrosus in a cat

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 13‐year‐old, male, neutered, indoor‐only, domestic long‐haired cat was presented with an 8‐month history of sneezing and a 2‐month history of epistaxis. Computed tomography demonstrated an irregular contrast‐enhancing soft tissue opacity within both nasal cavities and osteolysis of surrounding bony structures.
Leonel Frutuoso, Samuel Fowlie, Sean Haugland, Emma Corbett, Christopher Scudder   +4 more
wiley   +1 more source

Penetration Profile of Terbinafine Compared to Amorolfine in Mycotic Human Toenails Quantified by Matrix-Assisted Laser Desorption Ionization–Fourier Transform Ion Cyclotron Resonance Imaging

Infectious Diseases and Therapy
Introduction Amorolfine 5% lacquer is an established topical treatment for fungal infection of the nails. The success of topical therapy for onychomycosis depends on whether the permeated drug concentration in the deep nail bed is retained above the ...
Nicolas Joly-Tonetti, Raphael Legouffe, Aurore Tomezyk, Clémence Gumez, Mathieu Gaudin, David Bonnel, Martin Schaller   +6 more
doaj   +1 more source

Multiple Scaly Patches on the Scalp

JEADV Clinical Practice, EarlyView.
Feng‐Li Xu, Li‐Wen Zhang
wiley   +1 more source

Paediatric Acute Generalised and Localised Exanthematous Pustulosis: A Systematic Review

JEADV Clinical Practice, EarlyView.
Miranda K. Branyiczky, Megan Lowe, Eric McMullen, Shireen Dumont, Narachai Julanon, Vincent Piguet, Cathryn Sibbald   +6 more
wiley   +1 more source

Single Cold Atmospheric Plasma Therapy May Improve the Treatment Outcome of Canine Otitis Externa With Secondary Infection

Veterinary Dermatology, Volume 37, Issue 1, Page 103-110, February 2026.
Background: Otitis externa with secondary bacterial or yeast infection is a common problem in small animal practice. Cold physical plasma (CPP) has been reported to have antimicrobial activity in vitro. Results: Ears treated additionally with CPP showed lower otic scores after 21 days compared to nontreated ears, although this difference was not ...
Ralf S. Mueller, Cosima Bouassiba
wiley   +1 more source