Results 151 to 160 of about 8,169 (239)

Bone Marrow Pathology in Cold Agglutinin‐Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases

European Journal of Haematology, EarlyView.
ABSTRACT Cold agglutinin disease (CAD) is a rare form of autoimmune hemolytic anemia (AIHA). CAD occurs in the context of a small clonal B‐cell lymphoproliferation restricted to blood and/or bone marrow (BM), without overt or extramedullary lymphoma. The WHO‐HAEM5 introduced a description of the CAD‐associated lymphoproliferative disorder (CAD‐LPD) in ...
Anne‐Marie L. Becking, Sophie J. Bernelot Moens, Marie José Kersten, Femke V. M. Mulder, Steven T. Pals, Lianne Koens, Josephine M. I. Vos   +6 more
wiley   +1 more source

Tertiary lymphoid structures in breast cancer: formation, immune functions and clinical implications. [PDF]

Front Immunol
Dong W, Ai S, Shen X, Yao Y.
europepmc   +1 more source

Post‐Transplant Bendamustine as a Platform for Immune Modulation After Allogeneic Hematopoietic Cell Transplantation

European Journal of Haematology, EarlyView.
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo, Richard J. Simpson, Emmanuel Katsanis   +2 more
wiley   +1 more source

The biological characteristics of tertiary lymphoid structures in head and neck cancer. [PDF]

Front Immunol
Bai S, Wei Y, Liu F, Sun H, Zeng X, Zhang P.   +5 more
europepmc   +1 more source

Extranodal Marginal Zone Lymphoma: Integrating Etiology, Microenvironment, and Genetics Into Clinical Decision‐Making

European Journal of Haematology, EarlyView.
ABSTRACT Extranodal marginal zone lymphoma (EMZL) represents a unique paradigm among indolent B‐cell neoplasms, in which lymphomagenesis is frequently driven by chronic antigenic stimulation within tissue‐specific microenvironments. Persistent infectious or autoimmune triggers promote the development of ectopic lymphoid tissue and sustain B‐cell ...
Mamdouh Skafi, Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Marco Fiorillo, Eugenio Lucia, Graziella D'Arrigo, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Maria Eugenia Alvaro, Giovanni Tripepi, Fortunato Morabito, Massimo Gentile   +15 more
wiley   +1 more source

From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system

The FEBS Journal, EarlyView.
The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger, Alice Wiedmann, Rayan Hassan M. Elshikhidriss, Thomas Brunner   +3 more
wiley   +1 more source

Intestinal transplantation in Australia: Progress, challenges and future directions

Internal Medicine Journal, EarlyView.
Abstract Background Intestinal transplant is a rare procedure reserved for patients with intestinal failure who cannot be sustained on total parenteral nutrition due to severe, life‐threatening complications. This study aims to describe the activity and outcomes of intestinal transplantation undertaken in Australia.
Brooke Chapman, Darren Wong, Graham Starkey, Marcos Perini, Jason Yap, Adam Testro   +5 more
wiley   +1 more source

The CXCL13 hub in obesity-related metabolic inflammation: regulation of spatiotemporal heterogeneity and targeted strategies. [PDF]

J Endocrinol
Huang M, Chen X, Jiang Y, Liu T.
europepmc   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

High‐Dimensional Immune Profiling Identifies Circulating NKT‐Like Cells Associated With Severity Outcome in Acute Pancreatitis at Disease Onset

Immunology, EarlyView.
High‐dimensional spectral cytometry of peripheral blood mononuclear cells at hospital admission revealed that acute pancreatitis patients who subsequently developed moderately‐to‐severe disease exhibited a specific reduction of circulating CD2 + CD8dim NKT‐like cells, which appear to acquire an altered cytotoxic‐like phenotype upon IL‐15 stimulation ...
Carolina González de Castro, Mª. Lourdes Ruiz Rebollo, Paloma Cal‐Sabater, Elisa Arribas‐Rodríguez, Álvaro Martín‐Muñoz, Alejandro Gonzalez del Hierro, Marina Perez Mazzali, Jessica Matesanz‐Isabel, Hugo Gonzalo‐Benito, Sara Cuesta‐Sancho, David Bernardo   +10 more
wiley   +1 more source