Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development [PDF]
, 2018 Tertiary lymphoid structures (TLSs) display phenotypic and functional characteristics of secondary lymphoid organs, and often develop in tissues affected by chronic inflammation, as well as in certain inflammation-associated cancers where they are ...
Balic, Jesse J. +14 more
core +4 more sources
Sialendoscopic management of autoimmune sialadenitis: a review of literature [PDF]
, 2017 Autoimmune diseases of major salivary glands include Sjögren's syndrome and a complex of disorders classified as immunoglobulin G4-related diseases.
DE VINCENTIIS, Marco +6 more
core +2 more sources
O21 Analysis of B-cell infiltrates and tertiary lymphoid organ in lupus nephritis
, 2020 Background Renal impairment is the leading cause of morbidity and mortality in systemic lupus erythematosus. Tertiary lymphoid organs (TLO) are organized lymphoid structures that develop in response to inflammatory signals from tissues. They may organize
F. Touzani, A. Pozdzik
semanticscholar +1 more source
P03.03 Organization, function and gene expression of tertiary lymphoid structures in PDAC resembles lymphoid follicles in secondary lymphoid organs [PDF]
E-Poster Presentations, 2020 Background Secondary lymphoid organs (SLO) are involved in induction and enhancement of anti-tumor immune responses on different tumor entities. Recent evidence suggests that anti-tumor immune responses may also be induced or enhanced in the tumor microenvironment in so called tertiary lymphoid structures (TLS).
M Thelen +14 more
openaire +1 more source
Frontiers in Oncology, 2021 BackgroundLung adenocarcinoma (LUAD) is a highly mortal cancer. Tertiary lymphoid structures (TLS) are ectopic lymphoid organs with similar morphological and molecular characters to secondary lymphoid organ.
Hong Feng +10 more
doaj +1 more source
Regulatory T cells with multiple suppressive and potentially pro-tumor activities accumulate in human colorectal cancer [PDF]
, 2016 Tregs can contribute to tumor progression by suppressing antitumor immunity. Exceptionally, in human colorectal cancer (CRC), Tregs are thought to exert beneficial roles in controlling pro-tumor chronic inflammation.
BARNABA, Vincenzo +14 more
core +1 more source
F1000Research, 2018 Immunomodulatory therapies available for the treatment of patients with multiple sclerosis (MS) accomplish control and neutralization of peripheral immune cells involved in the activity of the disease cascade but their spectrum of action in the ...
Ana C. Londoño, Carlos A. Mora
doaj +1 more source
New Insights on the Pathogenesis of Takayasu Arteritis: Revisiting the Microbial Theory
Pathogens, 2018 Takayasu arteritis (TAK) is a chronic vasculitis that mainly affects the aorta, its major branches, and the pulmonary arteries. Since the description of the first case by Mikito Takayasu in 1908, several aspects of this rare disease, including the ...
J. Luis Espinoza +2 more
doaj +1 more source
Tertiary Lymphoid Organs Are Associated With Bacterial Dysbiosis in Chronic Rhinosinusitis. [PDF]
Int Forum Allergy RhinolISSN:2042 ...
Paramasivan S +9 more
europepmc +5 more sources
Early IL-1 signaling promotes iBALT induction after influenza virus infection [PDF]
, 2016 Inducible bronchus-associated lymphoid tissue (iBALT) is a long lasting tertiary lymphoid tissue that can be induced following influenza A virus (IAV) infection.
Deswarte, K. (Kim) +4 more
core +5 more sources