Results 41 to 50 of about 8,169 (239)
Editorial: Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity [PDF]
Frontiers in Immunology, 2017 No abstract available.
Yin, Changjun +3 more
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Role of tertiary lymphoid organs in the regulation of immune responses in the periphery
Cellular and Molecular Life Sciences, 2022 Tertiary lymphoid organs (TLOs) are collections of immune cells resembling secondary lymphoid organs (SLOs) that form in peripheral, non-lymphoid tissues in response to local chronic inflammation. While their formation mimics embryologic lymphoid organogenesis, TLOs form after birth at ectopic sites in response to local inflammation resulting in their ...
Amit I. Bery +5 more
openaire +2 more sources
BMC Immunology, 2020 Background Numerous data obtained by different research laboratories indicate that specific IgE production is triggered independently of specific IgG or IgA ones and so it is not linked to fully matured germinal centers formation in the secondary ...
Dmitrii Borisovich Chudakov +5 more
doaj +1 more source
Advanced Science, 2022 Tertiary lymphoid structures (TLSs) provide specialized niches for immune cells, resulting in improved prognoses for patients undergoing cancer immunotherapy.
Jae‐Won Lee +16 more
doaj +1 more source
Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes [PDF]
Diabetologia, 2021 AbstractAims/hypothesisWe and others previously reported the presence of tertiary lymphoid organs (TLOs) in the pancreas of NOD mice, where they play a role in the development of type 1 diabetes. Our aims here are to investigate whether TLOs are present in the pancreas of individuals with type 1 diabetes and to characterise their distinctive features ...
Éva Korpos +10 more
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Frontiers in Oncology, 2021 BackgroundLung adenocarcinoma (LUAD) is a highly mortal cancer. Tertiary lymphoid structures (TLS) are ectopic lymphoid organs with similar morphological and molecular characters to secondary lymphoid organ.
Hong Feng +10 more
doaj +1 more source
F1000Research, 2018 Immunomodulatory therapies available for the treatment of patients with multiple sclerosis (MS) accomplish control and neutralization of peripheral immune cells involved in the activity of the disease cascade but their spectrum of action in the ...
Ana C. Londoño, Carlos A. Mora
doaj +1 more source
New Insights on the Pathogenesis of Takayasu Arteritis: Revisiting the Microbial Theory
Pathogens, 2018 Takayasu arteritis (TAK) is a chronic vasculitis that mainly affects the aorta, its major branches, and the pulmonary arteries. Since the description of the first case by Mikito Takayasu in 1908, several aspects of this rare disease, including the ...
J. Luis Espinoza +2 more
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Frontiers in Immunology, 2019 The Crohn's-like lymphoid reaction (CLR) to colorectal cancer (CRC), a CRC-specific ectopic lymphoid reaction, is thought to play an important role in the host response to CRC.
Asaf Maoz +2 more
doaj +1 more source
EMBO Molecular Medicine, 2018 The development of chronic obstructive pulmonary disease (COPD) pathogenesis remains unclear, but emerging evidence supports a crucial role for inducible bronchus‐associated lymphoid tissue (iBALT) in disease progression.
Jie Jia +22 more
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