Results 21 to 30 of about 8,169 (239)
Controversial role of ILC3s in intestinal diseases: A novelty perspective on immunotherapy
ILC3s have been identified as crucial immune regulators that play a role in maintaining host homeostasis and modulating the antitumor response. Emerging evidence supports the idea that LTi cells play an important role in initiating lymphoid tissue ...
Yunshu Zhang +9 more
doaj +1 more source
Tertiary Lymphoid Organs in Cancer Tissues [PDF]
Tertiary lymphoid organs (TLOs) are induced postnatally in non-lymphoid tissues such as those affected by chronic infections, autoimmune diseases, and chronic allograft rejection, and also in cancer tissues. TLOs are thought to provide important lymphocytic functional environments for both cellular and humoral immunity, similar to lymph nodes or Peyer ...
Hiraoka, Nobuyoshi +2 more
openaire +2 more sources
From Lymphotoxin to Tertiary Lymphoid Structures and Beyond [PDF]
Nancy H Ruddle
exaly +2 more sources
Tertiary Lymphoid Organs in Lymphatic Malformations [PDF]
Examine lymphatic malformation lymphoid aggregates for the expression of tertiary lymphoid organ markers. Determine how lymphoid aggregate density relates to lymphatic malformation clinical features.Retrospective cohort study. Tissue and clinical data were reviewed from 29 patients in the Vascular Anomaly Database who represented the spectrum of head ...
Andrew L, Kirsh +4 more
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The 12-CK Score: Global Measurement of Tertiary Lymphoid Structures
There is emerging evidence that the adaptive anti-tumor activity may be orchestrated by secondary lymphoid organ-like aggregates residing in the tumor microenvironment.
Roger Li +10 more
doaj +1 more source
Tertiary lymphoid organs in infection and autoimmunity [PDF]
The lymph nodes (LNs) and spleen have an optimal structure that allows the interaction between T cells, B cells and antigen-presenting dendritic cells (DCs) on a matrix made up by stromal cells. Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation.
Katrijn Neyt +4 more
openaire +3 more sources
Long‐term B cell depletion associates with regeneration of kidney function
Background Chronic kidney disease (CKD) is a common condition that increases mortality and the risk of cardiovascular and other morbidities regardless of underlying renal condition. Chronic inflammation promotes renal fibrosis.
Susanne V. Fleig +10 more
doaj +1 more source
Posttransplant Tertiary Lymphoid Organs
Tertiary lymphoid organs (TLOs), also known as tertiary or ectopic lymphoid structures or tissues, are accumulations of lymphoid cells in sites other than canonical lymphoid organs, that arise through lymphoid neogenesis during chronic inflammation in autoimmunity, microbial infection, cancer, aging, and transplantation, the focus of this review. Lymph
openaire +2 more sources
Tertiary lymphoid organs in recalcitrant chronic rhinosinusitis [PDF]
The letter to the editor. ; Abstract not available ; Aden Lau, Susan Lester, Sophia Moraitis, Judy Ou, Alkis J.
Lau, A. +8 more
openaire +3 more sources
Artery Tertiary Lymphoid Organs: Powerhouses of Atherosclerosis Immunity [PDF]
Artery tertiary lymphoid organs (ATLOs) are atherosclerosis-associated lymphoid aggregates with varying degrees of complexity ranging from small T/B-cell clusters to well-structured lymph node-like though unencapsulated lymphoid tissues. ATLOs arise in the connective tissue that surrounds diseased arteries, i.e., the adventitia.
Changjun Yin +6 more
openaire +4 more sources

