Results 21 to 30 of about 8,803 (251)
Long‐term B cell depletion associates with regeneration of kidney function
Immunity, Inflammation and Disease, 2021 Background Chronic kidney disease (CKD) is a common condition that increases mortality and the risk of cardiovascular and other morbidities regardless of underlying renal condition. Chronic inflammation promotes renal fibrosis.
Susanne V. Fleig +10 more
doaj +1 more source
Posttransplant Tertiary Lymphoid Organs
Transplantation, 2023 Tertiary lymphoid organs (TLOs), also known as tertiary or ectopic lymphoid structures or tissues, are accumulations of lymphoid cells in sites other than canonical lymphoid organs, that arise through lymphoid neogenesis during chronic inflammation in autoimmunity, microbial infection, cancer, aging, and transplantation, the focus of this review. Lymph
openaire +2 more sources
Tertiary lymphoid organs in recalcitrant chronic rhinosinusitis [PDF]
Journal of Allergy and Clinical Immunology, 2017 The letter to the editor. ; Abstract not available ; Aden Lau, Susan Lester, Sophia Moraitis, Judy Ou, Alkis J.
Lau, A. +8 more
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Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. [PDF]
Clin J Am Soc Nephrol, 2014 Previous studies have identified inflammatory features that enable the prediction of renal outcome of IgA nephropathy (IgAN); however, validation of these findings is still needed. This prospective study was performed to determine the characteristics of renal interstitial infiltration and tertiary lymphoid organ (TLO) neogenesis in a cohort of Chinese ...
Pei G +11 more
europepmc +4 more sources
Artery Tertiary Lymphoid Organs: Powerhouses of Atherosclerosis Immunity [PDF]
Frontiers in Immunology, 2016 Artery tertiary lymphoid organs (ATLOs) are atherosclerosis-associated lymphoid aggregates with varying degrees of complexity ranging from small T/B-cell clusters to well-structured lymph node-like though unencapsulated lymphoid tissues. ATLOs arise in the connective tissue that surrounds diseased arteries, i.e., the adventitia.
Changjun Yin +6 more
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Tertiary Lymphoid Organs in Central Nervous System Autoimmunity [PDF]
Frontiers in Immunology, 2016 Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients. Autoreactive T cells are important drivers of the disease; however, the efficacy of B cell depleting therapies uncovered an essential role for B ...
Meike Mitsdoerffer +2 more
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Stroma cell priming in enteric lymphoid organ morphogenesis
Frontiers in Immunology, 2012 The lymphoid system is equipped with a network of specialized platforms located at strategic sites, which grant strict immune-surveillance and efficient immune responses.
Manuela eFerreira +2 more
doaj +1 more source
B cells and tertiary lymphoid organs in renal inflammation [PDF]
Kidney International, 2008 B lymphocytes are part of the inflammatory cells recruited to the human kidney in various disease settings. B cell infiltrates have been described in renal allografts, in acute and chronic interstitial nephritis, and the most common glomerular diseases like immunoglobulin A (IgA) and membranous nephropathy.
Segerer, S., Schlöndorff, D.
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Frontiers in Immunology, 2012 In this communication, the contribution of stromal, or non-hematopoietic, cells to the structure and function of lymph nodes (LNs), as canonical secondary lymphoid organs (SLOs), is compared to that of tertiary lymphoid tissue or organs (TLOs), also ...
Sharon eStranford, Nancy H. Ruddle
doaj +1 more source
Lymphotoxins Serve as a Novel Orchestrator in T1D Pathogenesis
Frontiers in Immunology, 2022 Type 1 diabetes (T1D) stems from pancreatic β cell destruction by islet reactive immune cells. Similar as other autoimmune disorders, there is no curative remedy for T1D thus far.
Shi-Wei Liu +4 more
doaj +1 more source