Results 21 to 30 of about 8,187 (242)
Tertiary lymphoid organs in infection and autoimmunity [PDF]
Trends in Immunology, 2012 The lymph nodes (LNs) and spleen have an optimal structure that allows the interaction between T cells, B cells and antigen-presenting dendritic cells (DCs) on a matrix made up by stromal cells. Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation.
Katrijn Neyt +4 more
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The 12-CK Score: Global Measurement of Tertiary Lymphoid Structures
Frontiers in Immunology, 2021 There is emerging evidence that the adaptive anti-tumor activity may be orchestrated by secondary lymphoid organ-like aggregates residing in the tumor microenvironment.
Roger Li +10 more
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Tertiary Lymphoid Organs in Lymphatic Malformations [PDF]
Lymphatic Research and Biology, 2011 Examine lymphatic malformation lymphoid aggregates for the expression of tertiary lymphoid organ markers. Determine how lymphoid aggregate density relates to lymphatic malformation clinical features.Retrospective cohort study. Tissue and clinical data were reviewed from 29 patients in the Vascular Anomaly Database who represented the spectrum of head ...
Andrew L, Kirsh +4 more
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Posttransplant Tertiary Lymphoid Organs
Transplantation, 2023 Tertiary lymphoid organs (TLOs), also known as tertiary or ectopic lymphoid structures or tissues, are accumulations of lymphoid cells in sites other than canonical lymphoid organs, that arise through lymphoid neogenesis during chronic inflammation in autoimmunity, microbial infection, cancer, aging, and transplantation, the focus of this review. Lymph
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Tertiary lymphoid organs in recalcitrant chronic rhinosinusitis [PDF]
Journal of Allergy and Clinical Immunology, 2017 The letter to the editor. ; Abstract not available ; Aden Lau, Susan Lester, Sophia Moraitis, Judy Ou, Alkis J.
Lau, A. +8 more
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Long‐term B cell depletion associates with regeneration of kidney function
Immunity, Inflammation and Disease, 2021 Background Chronic kidney disease (CKD) is a common condition that increases mortality and the risk of cardiovascular and other morbidities regardless of underlying renal condition. Chronic inflammation promotes renal fibrosis.
Susanne V. Fleig +10 more
doaj +1 more source
Renal interstitial infiltration and tertiary lymphoid organ neogenesis in IgA nephropathy. [PDF]
Clin J Am Soc Nephrol, 2014 Previous studies have identified inflammatory features that enable the prediction of renal outcome of IgA nephropathy (IgAN); however, validation of these findings is still needed. This prospective study was performed to determine the characteristics of renal interstitial infiltration and tertiary lymphoid organ (TLO) neogenesis in a cohort of Chinese ...
Pei G +11 more
europepmc +4 more sources
From Lymphotoxin to Tertiary Lymphoid Structures and Beyond [PDF]
Immunological ReviewsNancy Ruddle
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Artery Tertiary Lymphoid Organs: Powerhouses of Atherosclerosis Immunity [PDF]
Frontiers in Immunology, 2016 Artery tertiary lymphoid organs (ATLOs) are atherosclerosis-associated lymphoid aggregates with varying degrees of complexity ranging from small T/B-cell clusters to well-structured lymph node-like though unencapsulated lymphoid tissues. ATLOs arise in the connective tissue that surrounds diseased arteries, i.e., the adventitia.
Changjun Yin +6 more
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Tertiary Lymphoid Organs in Central Nervous System Autoimmunity [PDF]
Frontiers in Immunology, 2016 Multiple sclerosis (MS) is an autoimmune disease characterized by chronic inflammation in the central nervous system (CNS), which results in permanent neuronal damage and substantial disability in patients. Autoreactive T cells are important drivers of the disease; however, the efficacy of B cell depleting therapies uncovered an essential role for B ...
Meike Mitsdoerffer +2 more
openaire +4 more sources