Results 11 to 20 of about 8,187 (242)
Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer [PDF]
British Journal of Cancer, 2015 Y Ino, Kosuge T, T Kosuge
exaly +2 more sources
Tertiary lymphoid structures guided opportunities and challenges for immunotherapy in early gastroesophageal junction cancer and low rectal cancer [PDF]
Human Vaccines & ImmunotherapeuticsEarly-stage gastroesophageal junction cancer (GEJC) and low rectal cancer (LRC) pose a dilemma: surgery is often curative yet may cause lasting functional loss.
Qi Zou +8 more
doaj +2 more sources
IL-17 initiates tertiary lymphoid organ formation. [PDF]
Cell Mol Immunol, 2012 Chronic inflammatory infiltrates that take on the form of organized lymphoid organs are called tertiary lymphoid organs (TLOs). The inflammatory cytokine interleukin-17 is now found to be the critical participant driving the development of a type of TLO called inducible bronchus-associated lymphoid tissue (iBALT) in an animal model of neonatal ...
Zhang X, Lu B.
europepmc +4 more sources
S1PR1 regulates lymphatic valve development and tertiary lymphoid organ formation in the ileum [PDF]
Journal of Experimental MedicineIlaria Del Gaudio +2 more
exaly +2 more sources
Lymphoid Neogenesis and Tertiary Lymphoid Organs in Transplanted Organs [PDF]
Frontiers in Immunology, 2016 The progressive organization of immune effectors into functional ectopic lymphoid structures, named tertiary lymphoid organs (TLO), has been observed in many conditions in which target antigens fail to be eliminated by the immune system. Not surprisingly, TLO have been recurrently identified in chronically rejected allografts.
Koenig, Alice, Thaunat, Olivier
openaire +2 more sources
Tertiary Lymphoid Organs in Takayasu Arteritis [PDF]
Frontiers in Immunology, 2016 The role of B cells in the pathogenesis of Takayasu arteritis (TA) is controversial. We aimed to study the presence of tertiary lymphoid organs (TLOs) in the aortic wall of TA patients.Hematoxylin and eosin-stained sections from aorta specimens from patients with TA were screened for TLOs.
Marc eClement +15 more
openaire +3 more sources
Tertiary Lymphoid Organs in Cancer Tissues [PDF]
Frontiers in Immunology, 2016 Tertiary lymphoid organs (TLOs) are induced postnatally in non-lymphoid tissues such as those affected by chronic infections, autoimmune diseases, and chronic allograft rejection, and also in cancer tissues. TLOs are thought to provide important lymphocytic functional environments for both cellular and humoral immunity, similar to lymph nodes or Peyer ...
Hiraoka, Nobuyoshi +2 more
openaire +2 more sources
Chinese Journal of Lung Cancer, 2023 Lung cancer is the leading cause of cancer death, and non-small cell lung cancer (NSCLC) accounts for 85%. Immunotherapy has significantly improved the clinical prognosis of patients with NSCLC. However, because of the complexity and heterogeneousness of
Ying LIU +6 more
doaj +1 more source
Tertiary Lymphoid Organs in Rheumatoid Arthritis [PDF]
, 2020 Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease. RA mainly affects the joints, with inflammation of the synovial membrane, characterized by hyperplasia, neo-angiogenesis, and immune cell infiltration that drives local inflammation and, if untreated, can lead to joint destruction and disability.
Rivellese, F, Pontarini, E, Pitzalis, C
openaire +3 more sources
Controversial role of ILC3s in intestinal diseases: A novelty perspective on immunotherapy
Frontiers in Immunology, 2023 ILC3s have been identified as crucial immune regulators that play a role in maintaining host homeostasis and modulating the antitumor response. Emerging evidence supports the idea that LTi cells play an important role in initiating lymphoid tissue ...
Yunshu Zhang +9 more
doaj +1 more source