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, 2021 Testosterone is a hormone produced majorly by the testicles in adult human _ men. The hormone affects a man’s appearance and sexual development, stimulates sperm production and regulates a man’s sex drive. It also helps build muscles and bone mass. Testosterone production decreases with age.
Irene Porcari +2 more
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Drug, Healthcare and Patient Safety, 2023 Katherine Campbell,1 Akhil Muthigi,1 Armin Ghomeshi,2 Kyle Schuppe,3 Max D Sandler,4 Ranjith Ramasamy1 1Desai Sethi Urology Institute, University of Miami, Miami, Fl, 33136, USA; 2Herbert Wertheim College of Medicine, Florida International University ...
Campbell K +5 more
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The World Journal of Men's Health, 2023 Purpose: Testosterone replacement therapy (TRT) can potentially cause decreased spermatogenesis and subsequent infertility. Recent studies have suggested that 17-hydroxyprogesterone (17-OHP) is a reliable surrogate for intratesticular testosterone (ITT)
Parris Diaz +7 more
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Genomic and non-genomic effects of androgens in the cardiovascular system: clinical implications [PDF]
, 2017 The principle steroidal androgens are testosterone and its metabolite 5α-dihydrotestosterone (DHT), which is converted from testosterone by the enzyme 5α-reductase.
Ahmed, S. Faisal +4 more
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Testosterone and the heart [PDF]
International Journal of Clinical Practice, 2012 Several large scale studies in recent years have demonstrated increased cardiovascular mortality in men with low testosterone, especially those with existing cardiovascular disease and type 2 diabetes. In some patients the baseline measurement was a single total testosterone level, in others the association was seen only with free or bioavailable ...
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International Journal of Endocrinology, 2018 Background. Diagnosing polycystic ovary syndrome (PCOS) is based on ovulatory dysfunction, ovarian ultrasound data, and androgen excess. Total testosterone is frequently used to identify androgen excess, but testosterone is mainly bound to sex hormone ...
L. Antonio +10 more
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Therapeutic Advances in Endocrinology and Metabolism, 2022 Background: Masculinising hormone therapy with testosterone is used to align an individual’s physical characteristics with their gender identity. Standard testosterone doses and formulations recommended for hypogonadal cisgender men are typically ...
Brendan J. Nolan +7 more
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Molecular genetics and pathophysiology of 17 beta-hydroxysteroid dehydrogenase 3 deficiency. [PDF]
, 1996 Autosomal recessive mutations in the 17 beta-hydroxysteroid dehydrogenase 3 gene impair the formation of testosterone in the fetal testis and give rise to genetic males with female external genitalia.
Andersson, Stefan +14 more
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Gender ideology, same-sex peer group affiliation and the relationship between testosterone and dominance in adolescent boys and girls [PDF]
, 2010 Although the role of testosterone in the aetiology of social dominance is often suggested, surprisingly few studies have addressed the relationship between sex steroid hormones and dominance as a personality trait. In this paper, the relationship between
Kaufman, Jean +4 more
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Frontiers in Pharmacology, 2019 The growing interest in testosterone's effects on men's social behaviors, in particular aggressive, risk-taking, or status maintenance behaviors, is accompanied by a paucity of dose-dependent pharmacokinetic data. Examining the neurophysiological effects
Andrei A. Puiu +10 more
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