Results 41 to 50 of about 373,589 (236)

Fabrication of silastic testosterone enanthate implants to achieve virilizing levels of serum testosterone in swine

open access: yesMethodsX
The aim of this study was to create a continuous drug delivery system that would yield serum testosterone levels in sexually mature, female pigs consistent with serum testosterone levels of human transgender men.
Nirvana Mahabir, Annie E. Newell-Fugate
doaj   +1 more source

Testosterone and androstenedione concentrations in human testis and epididymis during the first two years of life [PDF]

open access: yes, 1983
Testosterone and androstenedione were measured in testicular and epididymal tissue of 37 previously healthy infants between 1 and 24 months of age who died suddenly. In half of the patients elevated plasma levels of cortisol and androstenedione suggested
Bidlingmaier, F.   +4 more
core   +1 more source

An Overview of Testosterone Therapy

open access: yesAmerican Journal of Men's Health, 2016
Millions of men, as a result of the natural aging process, injury, illness, and medical therapies, experience a decline in testosterone levels that necessitate a need for testosterone supplementation therapy (TST).
O. Danny Lee PhD, APRN-BC, CNE   +1 more
doaj   +1 more source

The enhancing effects of testosterone in exposure treatment for social anxiety disorder: a randomized proof-of-concept trial

open access: yesTranslational Psychiatry, 2021
Individuals with a social anxiety disorder (SAD) show hypofunctioning of the hypothalamus–pituitary-gonadal (HPG) axis, which is linked to social fear and avoidance behavior.
Moniek H. M. Hutschemaekers   +4 more
doaj   +1 more source

Transcriptomic and lipid profiling analysis reveals a functional interplay between testosterone and growth hormone in hypothyroid liver

open access: yesFrontiers in Endocrinology, 2023
Preclinical and clinical studies suggest that hypothyroidism might cause hepatic endocrine and metabolic disturbances with features that mimic deficiencies of testosterone and/or GH.
Leandro Fernández-Pérez   +12 more
doaj   +1 more source

Sterol 3β-glucosyltransferase biocatalysts with a range of selectivities, including selectivity for testosterone [PDF]

open access: yes, 2013
The main objectives of this work were to characterise a range of purified recombinant sterol 3β-glucosyltransferases and show that rational sampling of the diversity that exists within sterol 3β-glucosyltransferase sequence space can result in a range of
Altschul   +30 more
core   +1 more source

Testosterone increases the virulence traits of uropathogenic Escherichia coli

open access: yesFrontiers in Microbiology
Uropathogenic Escherichia coli (UPEC) is the most common cause of urinary tract infections (UTIs) in humans. Testosterone negatively impacts UTIs by affecting the immune response, leading to higher susceptibility of chronic cystitis in individuals with ...
Rongrong Wu   +3 more
doaj   +1 more source

Novas perspectivas no diagnóstico do hipogonadismo pediátrico masculino: a importância do AMH como marcador de células de Sertoli [PDF]

open access: yes, 2011
Sertoli cells are the most active cell population in the testis during infancy and childhood. In these periods of life, hypogonadism can only be evidenced without stimulation tests, if Sertoli cell function is assessed.
Grinspon, Romina, Rey, Rodolfo Alberto
core   +2 more sources

p38 mediates T-2 toxin-induced Leydig cell testosterone synthesis disorder

open access: yesEcotoxicology and Environmental Safety, 2023
T-2 toxin is an unavoidable food and feed contaminant that seriously threatens human and animal health. Exposure to T-2 toxin can cause testosterone synthesis disorder in male animals, but the molecular mechanism is still not completely clear.
Xu Yang   +9 more
doaj   +1 more source

Sustained testosterone suppression: prognostic indicator in advanced hormone sensitive prostate cancer

open access: yesFrontiers in Endocrinology
ObjectiveWe aimed to investigate the relationship between sustained testosterone suppression and clinical outcomes in advanced hormone-sensitive prostate cancer (aHSPC), which integrates longitudinal testosterone with castration duration to predict tumor
Dongsheng Ma   +4 more
doaj   +1 more source

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