Whole genome analysis of carbapenem resistant <i>Acinetobacter baumannii</i> isolates from healthcare-associated infections in Dakar, Senegal. [PDF]
Ndiaye I +12 more
europepmc +1 more source
Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley +1 more source
Synthetic overlapping genes stabilize genetic systems. [PDF]
Leonard SP +7 more
europepmc +1 more source
Abstract figure legend We used an intersectional approach with recombinase‐expressing mice and adeno‐associated virus to map and modulate distinct nociceptive afferents in the vagal ganglia. TRPV1+P2X2+ neurons resided in the nodose ganglion (N), innervated the lungs (many projected into the alveoli) but not the trachea, and projected to the nucleus ...
Mayur J. Patil +11 more
wiley +1 more source
Genomic analysis of ST117, 155, 1011, 167, 744, and 17391 in poultry-associated multidrug resistant Escherichia coli isolates from India. [PDF]
P R +6 more
europepmc +1 more source
ABSTRACT Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy, and 5%–20% of newly diagnosed patients present with hyperleukocytosis (HL). HL, most often defined as WBC > 100 000/μL, is a hematologic emergency associated with severe complications, early mortality, and poor prognosis, requiring immediate intervention.
Vojtech Latal +10 more
wiley +1 more source
Development, validation, and application of SYBR green-based qPCR assays for detection and quantification of <i>tetA, tetB</i>, and <i>tetO</i> genes in poultry and associated environments. [PDF]
Piccirillo A, Tolosi R, Laconi A.
europepmc +1 more source
The studied strains, LIN_NWU_CNKT and LIN5_NWU_CNKT, exhibit invasiveness, pathogenicity, and MDR profiles. The isolation of these strains from food products and water underscores their significant public health implications, particularly in the context of the “One Health” concept.
Christ‐Donald Kaptchouang Tchatchouang +3 more
wiley +1 more source
GADD45B knockout in hematopoietic stem cells causes DNA methylation changes that mirror some age‐associated patterns but don't affect HSC function or gene expression. We created a searchable database to identify consistently reported methylation sites associated with age‐related HSC functional decline.
Wakako Kuribayashi +5 more
wiley +1 more source
Characterization using ultra-deep sequencing of the intra-host distribution of the mutations associated with H. pylori antibiotic resistance. [PDF]
Chaufour L +7 more
europepmc +1 more source

