Results 11 to 20 of about 472,621 (287)

“TET-on” pluripotency [PDF]

Cell Research, 2013
Recent studies have uncovered a specific role of TET proteins in reprogramming somatic cells to induced pluripotent stem cells, a process where O-linked β-N-acetylglucosamine transferase may play a crucial role.
Ping, Wang, Jing, Qu, Min-Zu, Wu, Weizhou, Zhang, Guang-Hui, Liu, Juan Carlos, Izpisua Belmonte   +5 more
openaire   +2 more sources

Sporadic Dissemination of tet(X3) and tet(X6) Mediated by Highly Diverse Plasmidomes among Livestock-Associated Acinetobacter

Microbiology Spectrum, 2021
The emergence of high-level tigecycline resistance mediated by plasmid-borne tet(X) genes greatly threatens the clinical effectiveness of tigecycline. However, the dissemination pattern of plasmid-borne tet(X) genes remains unclear. We here recovered tet(
Ying-Ying Cheng, Yang Liu, Yong Chen, Fu-Man Huang, Rong-Chang Chen, Yong-Hong Xiao, Kai Zhou   +6 more
doaj   +1 more source

Tertiary-Treated Municipal Wastewater is a Significant Point Source of Antibiotic Resistance Genes Into Duluth-Superior Harbor [PDF]

, 2011
In this study, the impact of tertiary-treated municipal wastewater on the quantity of several antibiotic resistance determinants in Duluth-Superior Harbor was investigated by collecting surface water and sediment samples from 13 locations in Duluth ...
Allen H. K., Alonso A., Amann R. I., Andersson D. I., Arthurson V., Auerbach E. A., Benson D. A., Berhardt A. E., Berhardt A. E., Canton R., Cardinale M., Chopra I., Cotner J. B., David T. Tan, Davies J., Diehl D. L., D’Costa V. M., Ghosh S., Graham D. W., Jessica J. Eichmiller, Levy S. B., Levy S. B., Ling L. L., Lipsitch M., Martínez J., Merlin C., Mi Yan, Moura A., Munir M., Nelson D. K., Novo A., Patrick J. McNamara, Pruden A., Ramsden S. J., Sambrook J., Seurinck S., Smith D. L., Sommer M. O. A., Staley J. T., Storteboom H., Tchobanoglous G., Thioulouse J., Thompson J. D., Timothy M. LaPara, Tucker R. Burch, Xi C., Yi L., Zhang T., Zhang X., Zhang X.-X.   +49 more
core   +3 more sources

Functional analysis of the Arabidopsis TETRASPANIN gene family in plant growth and development [PDF]

, 2015
TETRASPANIN (TET) genes encode conserved integral membrane proteins that are known in animals to function in cellular communication during gamete fusion, immunity reaction and pathogen recognition.
Himanen, Kristiina, Muto, Antonella, Neyt, Pia, Van de Velde, Jan, Van Lijsebettens, Maria, Vandepoele, Klaas, Wang, Feng   +6 more
core   +1 more source

An Epigenetic Tet a Tet with Pluripotency [PDF]

Cell Stem Cell, 2011
DNA and chromatin-modifying enzymes establish an ESC/iPSC-specific epigenomic landscape that is linked to a network of pluripotency genes and influences differentiation potential. In this issue of Cell Stem Cell, Koh et al. (2011) highlight Tet1 and Tet2 as key players in this network of coordinated genetic and epigenetic control.
openaire   +2 more sources

Occurrence and Molecular Characterization of Abundant tet(X) Variants Among Diverse Bacterial Species of Chicken Origin in Jiangsu, China

Frontiers in Microbiology, 2021
Many novel tigecycline-inactivating enzymes encoded by tet(X) variants from different bacteria were discovered since the plasmid-mediated tet(X3) and tet(X4) genes conferring high-level resistance to tigecycline in Enterobacterales and Acinetobacter were
Yingshan Li, Yingshan Li, Kai Peng, Kai Peng, Yi Yin, Yi Yin, Xinran Sun, Xinran Sun, Wenhui Zhang, Wenhui Zhang, Ruichao Li, Ruichao Li, Ruichao Li, Zhiqiang Wang, Zhiqiang Wang   +14 more
doaj   +1 more source

5mC-hydroxylase activity is influenced by the PARylation of TET1 enzyme [PDF]

, 2015
5-hydroxymethylcytosine is a new epigenetic modification deriving from the oxidation of 5-methylcytosine by the TET hydroxylase enzymes. DNA hydroxymethylation drives DNA demethylation events and is involved in the control of gene expression ...
CAIAFA, Paola, CICCARONE, FABIO, VALENTINI, ELISABETTA, ZAMPIERI, Michele   +3 more
core   +2 more sources

Comprehensive mapping of 5-hydroxymethylcytosine epigenetic dynamics in axon regeneration

Epigenetics, 2017
In contrast to central nervous system neurons, dorsal root ganglia (DRG) neurons can switch to a regenerative state after peripheral axotomy. In a screen for chromatin regulators of the regenerative responses in this conditioning lesion paradigm, we ...
Yong-Hwee Eddie Loh, Andrew Koemeter-Cox, Mattéa J. Finelli, Li Shen, Roland H. Friedel, Hongyan Zou   +5 more
doaj   +1 more source

Multidrug-resistant Escherichia coli and Tetracycline-resistant Enterococcus faecalis in wild raptors of Alabama and Georgia, USA [PDF]

, 2019
Wild birds inhabit in a wide variety of environments and can travel great distances. Thus, wild birds can possibly spread antimicrobial resistance along the way, and this may represent a potential public health concern.
Bellah, Jamie, Butaye, Patrick, Hathcock, Terri, Kang, Yuan, Mobley, Tyler, Poudel, Anil, Raiford, Donna, Wang, Chengming   +7 more
core   +1 more source

Uncovering the diverse hosts of tigecycline resistance gene tet(X4) in anaerobic digestion systems treating swine manure by epicPCR

Water Research X, 2023
The tet(X4) gene is a clinically important tigecycline resistance gene and has shown high persistence in livestock-related environments. However, the bacterial hosts of tet(X4) remain unknown due to the lack of appropriate approaches.
Shiting Dai, Qing He, Ziming Han, Wenli Shen, Ye Deng, Yang Wang, Wei Qiao, Min Yang, Yu Zhang   +8 more
doaj   +1 more source