Results 41 to 50 of about 5,278 (159)

Adrenaline Auto‐Injectors for Preventing Fatal Anaphylaxis

Clinical &Experimental Allergy, Volume 55, Issue 1, Page 19-35, January 2025.
During 35 years of increasing Adrenaline Autoinjector prescribing, there has been no obvious reduction in numbers of fatal anaphylaxis cases. Animal and human studies suggest intravenous adrenaline infusion, with appropriate fluid resuscitation, prevents fatal anaphylaxis.
Marcus Sim, Vibha Sharma, Karen Li, Mary Hazel Gowland, Tomaz Garcez, Cassandra Shilladay, Richard Pumphrey, Nandinee Patel, Paul J. Turner, Robert J. Boyle   +9 more
wiley   +1 more source

Possível interferência da antitoxina tetânica pré-existente, na vacinação antitetânica Possible interference of pre-existing tetanus antitoxin in antitetanus immunization

Revista de Saúde Pública, 1981
Estudou-se qual a possível interferência no desenvolvimento da imunidade antitetânica ativa em cobaias e camundongos, filhos de fêmeas vacinadas contra o tétano em diferentes épocas durante o período da prenhês.
Rosalvo Guidolin, Flávio Zelante, Elide H. G. Rocha Medeiros, Paulo Roberto Vitali Lacreta   +3 more
doaj   +1 more source

Coxofemoral luxation as a complication of localised tetanus in a cat

Journal of Feline Medicine and Surgery Open Reports, 2022
Case summary A 9-month-old male neutered domestic shorthair cat presented 2 weeks after castration with a 48 h history of acute-onset lateral recumbency and severe hindlimb rigidity.
Cecilia-Gabriella Danciu, Joshua Milgram, Ciprian Andrei Ober, Flaviu Alexandru Tăbăran, Helga Demény, Orit Chai   +5 more
doaj   +1 more source

The challenges and breakthroughs in the development of diagnostic monoclonal antibodies

VIEW, Volume 5, Issue 4, August 2024.
This study has systematically organized the discovery of antibodies into three stages and analyzed the advantages and disadvantages of each stage. Meanwhile, This study deeply analyzes challenges, proposing innovative strategies for the next generation of diagnostic antibody development. Aimed at moving closer to the gold standard of antibody discovery,
Jing Wang, Qitao Song, Tao Yang, Yuanli Li, Lihua Zhang, Jiayan Li, Feifei Liu, Yanyin Lin, Xiaoxia Xu, Yu Heng, Lulai Xu, Shun Zhang, Jiahui Zhou, Yunbo Liu, Lingyuan Kong, Dingbin Tang, Chengdong Ji, Bing Tan, Pu Liao, Nengke Pan, Weijing Yi, Zhanhui Wang   +21 more
wiley   +1 more source

Retrospective study of tetanus in 18 dogs—Causes, management, complications, and immunological status

Frontiers in Veterinary Science, 2023
ObjectiveTetanus is a severe neurologic disease caused by Clostridium tetani, resulting in spastic paralysis. Canine tetanus is associated with serious complications such as aspiration and a high mortality rate of up to 50%.Materials and methodsMedical ...
Stefanie Dörfelt, Christine Mayer, Georg Wolf, Reinhard K. Straubinger, Andrea Fischer, Katrin Hartmann, Rene Dörfelt   +6 more
doaj   +1 more source

Subclinical infection and potential shedding routes of equine parvovirus‐hepatitis among hospitalized horses in Austria

Journal of Veterinary Internal Medicine, Volume 38, Issue 4, Page 2373-2379, July/August 2024.
Abstract Background Equine parvovirus hepatitis (EqPV‐H) can cause Theiler's disease and subclinical hepatitis in horses. Objectives Assess the frequency of subclinical EqPV‐H infection in hospitalized horses and to study viral transmission by investigating potential shedding routes.
Dilara Lale, Esther E. Dirks, Irina Preining, Manolis Lyrakis, Andre Gömer, Eike Steinmann, Jessika‐M. V. Cavalleri, Anna Sophie Ramsauer   +7 more
wiley   +1 more source

What is the role of microbial biotechnology and genetic engineering in medicine?

MicrobiologyOpen, Volume 13, Issue 2, April 2024.
Microbial biotechnology, the technological application of microorganisms, has been instrumental in producing significant natural bioactive products. These include antibiotics, antifungals, anticancer drugs, antiparasitics, antivirals, immunosuppressants, toxoid vaccines, and therapeutic enzymes.
Fernando Santos‐Beneit
wiley   +1 more source

A novel single-domain antibody multimer that potently neutralizes tetanus neurotoxin

Vaccine: X, 2021
Tetanus antitoxin, produced in animals, has been used for the prevention and treatment of tetanus for more than 100 years. The availability of antitoxins, ethical issues around production, and risks involved in the use of animal derived serum products ...
Hans de Smit, Bart Ackerschott, Robert Tierney, Paul Stickings, Michiel M. Harmsen   +4 more
doaj   +1 more source

Pastern dermatitis outbreak associated with toxigenic and non‐toxigenic Corynebacterium diphtheriae and non‐toxigenic Corynebacterium ulcerans at a horse stable in Finland, 2021

Zoonoses and Public Health, Volume 71, Issue 2, Page 127-135, March 2024.
Abstract Aims Corynebacterium diphtheriae and Corynebacterium ulcerans, when producing toxin, are the cause of diphtheria, a potentially life‐threatening illness in humans. Horses (Equus ferus caballus) are known to be susceptible to infection that may manifest clinically on rare occasions.
Thomas Sven Christer Grönthal, Anna Karoliina Lehto, Sanna Sofia Aarnio, Eva Katarina Eskola, Elina Marjaana Aimo‐Koivisto, Teemu Karlsson, Heli Irmeli Koskinen, Alex‐Mikael Barkoff, Qiushui He, Taru Lienemann, Ruska Rimhanen‐Finne, Anna Mykkänen   +11 more
wiley   +1 more source

Zoonotic transmission of diphtheria toxin‐producing Corynebacterium ulcerans

Zoonoses and Public Health, Volume 71, Issue 2, Page 157-169, March 2024.
Abstract Background Diphtheria caused by toxin‐producing Corynebacterium ulcerans is a re‐emerging human disease that can cause local and systemic sequelae. In Australia, toxigenic diphtheria is a rare notifiable communicable disease, due to high‐vaccination coverage. The public health management of cutaneous cases of toxigenic C.
Adeline Hillan, Tristan Gibbs, Graham Weaire‐Buchanan, Tracy Brown, Stanley Pang, Suzanne P. McEvoy, Erica Parker   +6 more
wiley   +1 more source