Results 41 to 50 of about 8,326 (205)

Generalized Tetanus in a Case of an Immunized Patient

open access: yesInternational Journal of Infectious Diseases, 2022
Purpose: Tetanus is an infectious disease rarely occurring in developed countries, but its severity, and the possibility of developing multiple complications, some life-threatening, made its recognition and treatment to be a medical emergency.
N. Negrut, A. Fitero
doaj   +1 more source

Age-Related Dynamics in Post-Vaccine Antibody Immune Response to Diphtheria and Tetanus Toxoid in Bulgarian Subjects

open access: yesActa Medica Bulgarica, 2021
In this study, we investigated the age-related dynamics in post-vaccine humoral immunity to diphtheria (DT) and tetanus (TT) toxoids in the Bulgarian population.
Lesichkova S.   +5 more
doaj   +1 more source

Survival in canine tetanus – retrospective analysis of 42 cases (2006–2020)

open access: yesFrontiers in Veterinary Science, 2022
ObjectiveTo define factors associated with survival in dogs with tetanus and to evaluate the prognostic significance of an established severity classification scheme.MethodsMedical records of dogs with the clinical diagnosis of tetanus were ...
Johannes Zitzl   +4 more
doaj   +1 more source

Botulinum Neurotoxins: History, Mechanism, and Applications. A Narrative Review

open access: yesJournal of Neurochemistry, Volume 169, Issue 8, August 2025.
Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, bind irreversibly to presynaptic cholinergic nerve terminals and exploit a zinc‐dependent mechanism to cleave SNARE proteins, blocking acetylcholine release and causing flaccid paralysis.
Arik Monash   +3 more
wiley   +1 more source

Adrenaline Auto‐Injectors for Preventing Fatal Anaphylaxis

open access: yesClinical &Experimental Allergy, Volume 55, Issue 1, Page 19-35, January 2025.
During 35 years of increasing Adrenaline Autoinjector prescribing, there has been no obvious reduction in numbers of fatal anaphylaxis cases. Animal and human studies suggest intravenous adrenaline infusion, with appropriate fluid resuscitation, prevents fatal anaphylaxis.
Marcus Sim   +9 more
wiley   +1 more source

Possível interferência da antitoxina tetânica pré-existente, na vacinação antitetânica Possible interference of pre-existing tetanus antitoxin in antitetanus immunization

open access: yesRevista de Saúde Pública, 1981
Estudou-se qual a possível interferência no desenvolvimento da imunidade antitetânica ativa em cobaias e camundongos, filhos de fêmeas vacinadas contra o tétano em diferentes épocas durante o período da prenhês.
Rosalvo Guidolin   +3 more
doaj   +1 more source

Coxofemoral luxation as a complication of localised tetanus in a cat

open access: yesJournal of Feline Medicine and Surgery Open Reports, 2022
Case summary A 9-month-old male neutered domestic shorthair cat presented 2 weeks after castration with a 48 h history of acute-onset lateral recumbency and severe hindlimb rigidity.
Cecilia-Gabriella Danciu   +5 more
doaj   +1 more source

Retrospective study of tetanus in 18 dogs—Causes, management, complications, and immunological status

open access: yesFrontiers in Veterinary Science, 2023
ObjectiveTetanus is a severe neurologic disease caused by Clostridium tetani, resulting in spastic paralysis. Canine tetanus is associated with serious complications such as aspiration and a high mortality rate of up to 50%.Materials and methodsMedical ...
Stefanie Dörfelt   +6 more
doaj   +1 more source

Immunogenicity of a low-dose diphtheria, tetanus and acellular pertussis combination vaccine with either inactivated or oral polio vaccine compared to standard-dose diphtheria, tetanus, acellular pertussis when used as a pre-school booster in UK children : a 5-year follow-up of a randomised controlled study [PDF]

open access: yes, 2015
This serological follow up study assessed the kinetics of antibody response in children who previously participated in a single centre, open-label, randomised controlled trial of low-dose compared to standard-dose diphtheria booster preschool ...
Baudin, M.   +8 more
core   +1 more source

The challenges and breakthroughs in the development of diagnostic monoclonal antibodies

open access: yesVIEW, Volume 5, Issue 4, August 2024.
This study has systematically organized the discovery of antibodies into three stages and analyzed the advantages and disadvantages of each stage. Meanwhile, This study deeply analyzes challenges, proposing innovative strategies for the next generation of diagnostic antibody development. Aimed at moving closer to the gold standard of antibody discovery,
Jing Wang   +21 more
wiley   +1 more source

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