Results 41 to 50 of about 15,945 (179)
ABSTRACT Background and Aims Tetanus, caused by Clostridium tetani, results in rigor spasms and remains as major cause of mortality in areas with poor vaccination and sanitation. Mortality has been cited to be 20%–55% in Ethiopia, possibly due to variation in healthcare, immunization, and intensive care access.
Mulugeta Tesfaw +3 more
wiley +1 more source
The Cinderella tree, Quillaja saponaria – A soap story
Our current understanding of plants has been shaped by the entwining of different cultures. The Chilean soapbark tree, traditionally valued as a source of natural soap, was shown by serendipitous research in France in the 1900s to produce compounds that can boost the immune response to vaccines.
Anne Osbourn
wiley +1 more source
High-level Expression of Tetanus Toxin Fragment C in Escherichia coli [PDF]
Fragment C is the C-terminal domain of the heavy chain of tetanus toxin that can promote the immune response against the lethal dose of this toxin. Therefore, this portion can be considered as a candidate vaccine against tetanus infection, which occurs ...
K. Aghaiypour, R. Teymourpour
doaj +1 more source
Myeloid‐derived suppressor cells (MDSCs) are key contributors to cancer immunotherapy failure and major targets in new therapeutic strategies. We highlight therapeutic approaches to counteract their immunosuppressive functions and discuss recent efforts to optimize drug delivery for controlling MDSCs, focusing on resiquimod as a representative drug ...
Yanying He, Yoon Yeo
wiley +1 more source
A needle in a haystack: Navigating equine injectable drug reactions
Equine Veterinary Education, EarlyView.
G. D. Hallowell
wiley +1 more source
Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino +10 more
wiley +1 more source
Bafilomycin A1, a vacuolar H+-ATPase inhibitor, and botulinum toxin B and tetanus toxin, both vesicle fusion inhibitors, are widely known exocytosis blockers that have been used to inhibit the presynaptic release of neurotransmitters.
Dong Ho Woo +4 more
doaj +1 more source
An Unusual Case of Tetanus Masquerading as an Acute Abdomen: A Case Report
Introduction: Tetanus is an acute onset neurological disease that is often lethal. It has a high disease burden in low and middle-income countries. Tetanus is caused by a toxin made by spores of the bacterium Clostridium tetani, which are found in soil ...
Rahul Kumar Thakur +3 more
doaj +1 more source
Engram Synapses and Synapse Dynamics in Memory Processing
Learning‐induced neuronal activity dynamically rewires synapses, altering their formation and elimination rates in task‐related regions. In vivo two‐photon imaging has revealed that activity‐driven presynaptic, postsynaptic, and astrocytic mechanisms regulate synaptogenesis and axonal bouton engulfment.
Yongmin Sung +3 more
wiley +1 more source
Immunoenzimatic detection of the Clostridium tetani bacterial toxin: an alternative to mice bioassays. Cell-free extracts from 20 strains of Clostridium tetani isolated from soil samples, were tested for tetanus toxin production using an enzyme ...
Fernando Chaves +2 more
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