Toxin-mediated competition in weakly motile bacteria [PDF]
2019, J. Theor. Biol. 480 , 205-217, 2019 Many bacterial species produce toxins that inhibit their competitors. We model this phenomenon by extending classic two-species Lotka-Volterra competition in one spatial dimension to incorporate toxin production by one species. Considering solutions comprising two adjacent single-species colonies, we show how the toxin inhibits the susceptible species ...
arxiv +1 more source
Neutralization of Lethal Potency of Tetanus Toxin using Phage Display Produced scFv Antibody [PDF]
, 2021 Background and Aim: Phage display technology provides a new approach for making human antibody fragments that could be applicable in passive immune therapy.
Abbasi, Ebrahim +2 more
core +2 more sources
Using Multiscale Molecular Dynamics Simulations to Obtain Insights into Pore Forming Toxin Mechanisms [PDF]
Methods in Enzymology (Chapter Sixteen), 2021, 2020 Pore forming toxins (PFTs) are virulent proteins released by several species, including many strains of bacteria, to attack and kill host cells. In this article, we focus on the utility of molecular dynamics (MD) simulations and the molecular insights gleaned from these techniques on the pore forming pathways of PFTs.
arxiv +1 more source
The Toxin and Antitoxin of Tetanus [PDF]
The Boston Medical and Surgical Journal, 1898 n ...
openaire +3 more sources
Fragment C of Tetanus Toxin: New Insights into Its Neuronal Signaling Pathway
International Journal of Molecular Sciences, 2012 When Clostridium tetani was discovered and identified as a Gram-positive anaerobic bacterium of the genus Clostridium, the possibility of turning its toxin into a valuable biological carrier to ameliorate neurodegenerative processes was inconceivable ...
A. Calvo +5 more
semanticscholar +1 more source
Immunogenicity test of tetanus component in adsorbed vaccines by toxin binding inhibition test
Memorias do Instituto Oswaldo Cruz, 2002 Samples from 20 lots of diphtheria-tetanus (adult use dT) vaccine and from 20 lots of diphtheria-tetanus-pertussis (DTP) vaccine were used to standardize and validate the in vitro toxin binding inhibition (ToBI) test for the immunogenicity test of the ...
Denise Cristina Souza Matos +5 more
doaj +1 more source
Tetanus in Animals — Summary of Knowledge
Folia Veterinaria, 2020 Tetanus is a neurologic non-transmissible disease (often fatal) of humans and other animals with a worldwide occurrence. Clostridium tetani is the spore producing bacillus which causes the bacterial disease.
Malinovská Z., Čonková E., Váczi P.
doaj +1 more source
Altered expression of the voltage-gated calcium channel subunit α2δ-1: a comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain. [PDF]
, 2014 The auxiliary α2δ-1 subunit of voltage-gated calcium channels is up-regulated in dorsal root ganglion neurons following peripheral somatosensory nerve damage, in several animal models of neuropathic pain.
Bauer, CS +5 more
core +1 more source
, 2013 The commercial production of purified tetanus toxoid mainly depends on the effective separation of the bacterial toxin and toxoid from large volumes of fermentation broth of Clostridium tetani (Harvard 49205) vaccine strain. Tangential flow or cross-flow
C. Muniandi, K. Mani, R. Subashkumar
semanticscholar +1 more source
The monoclonal antibody 26 raised against tetanus toxoid also recognizes tetanus toxin and b2-glycoprotein I – its binding properties in vitro and potential applications [PDF]
Journal of the Serbian Chemical Society, 2009 A murine monoclonal IgG1 antibody, marked as MAb26, specific for tetanus toxoid has been immunochemically characterized. By performing enzyme-linked immunosorbent assays (ELISAs) and western blot analyses, it was demonstrated that MAb26 reacted with ...
ALEKSANDRA B. INIĆ-KANADA +4 more
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