Results 61 to 70 of about 328,500 (323)
Modeling sRNA-regulated Plasmid Maintenance [PDF]
, 2016 We study a theoretical model for the toxin-antitoxin (hok/sok) mechanism for plasmid maintenance in bacteria. Toxin-antitoxin systems enforce the maintenance of a plasmid through post-segregational killing of cells that have lost the plasmid. Key to their function is the tight regulation of expression of a protein toxin by an sRNA antitoxin.
arxiv +1 more source
Tetanus Toxin C-Fragment: The Courier and the Cure?
Toxins, 2010 In many neurological disorders strategies for a specific delivery of a biological activity from the periphery to the central nervous system (CNS) remains a considerable challenge for successful therapy. Reporter assays have established that the non-toxic
J. Toivonen, S. Oliván, R. Osta
semanticscholar +1 more source
CsrA and its regulators control the time-point of ColicinE2 release in Escherichia coli [PDF]
Scientific Reports 8, 6537 (2018), 2018 The bacterial SOS response is a cellular reaction to DNA damage, that, among other actions, triggers the expression of colicin - toxic bacteriocins in Escherichia coli that are released to kill close relatives competing for resources. However, it is largely unknown, how the complex network regulating toxin expression controls the time-point of toxin ...
arxiv +1 more source
THE DISTRIBUTION OF TETANUS TOXIN IN THE BODY [PDF]
The American Journal of the Medical Sciences, 1916 n ...
openaire +3 more sources
Environmental toxicity influences disease spread in consumer population [PDF]
arXiv, 2022 The study of infectious disease has been of interest to ecologists since long. The initiation of epidemic and the long term disease dynamics are largely influenced by the nature of the underlying consumer (host)-resource dynamics. Ecological traits of such systems may be often modulated by toxins released in the environment due to ongoing anthropogenic
arxiv
Journal of Veterinary Diagnostic Investigation, 2020 Tetanus is a neurologic disease of humans and animals characterized by spastic paralysis. Tetanus is caused by tetanus toxin (TeNT) produced by Clostridium tetani, an environmental soilborne, gram-positive, sporulating bacterium.
M. Popoff
semanticscholar +1 more source
Chemical warfare and survival strategies in bacterial range expansions [PDF]
J. R. Soc. Interface 11, 20140172 (2014), 2014 Dispersal of species is a fundamental ecological process in the evolution and maintenance of biodiversity. Limited control over ecological parameters has hindered progress in understanding of what enables species to colonise new area, as well as the importance of inter-species interactions.
arxiv +1 more source
Isolated Light Chain of Tetanus Toxin Inhibits Exocytosis: Studies in Digitonin-Permeabilized Cells [PDF]
, 1989 Previous work indicates that the heavy chain of tetanus toxin is responsible for the binding of the toxin to the neuronal membrane and its subsequent internalization.
Bittner, Mary A. +2 more
core +1 more source
Botulinum and Tetanus Neurotoxins.
Annual Review of Biochemistry, 2019 Botulinum neurotoxins (BoNTs) and tetanus neurotoxin (TeNT) are the most potent toxins known and cause botulism and tetanus, respectively. BoNTs are also widely utilized as therapeutic toxins.
M. Dong, G. Masuyer, P. Stenmark
semanticscholar +1 more source
Interdisciplinary Medicine, EarlyView.Abstract The skin, as the body's largest organ, plays essential roles in protection, immune regulation, and homeostasis. Skin trauma, especially chronic wounds such as diabetic ulcers, poses significant clinical challenges. Traditional treatments, while often effective, can be costly and pose risks.
Boxiang Yang +12 more
wiley +1 more source