Results 61 to 70 of about 318,498 (273)

Understanding the rationale for metronidazole use in dogs and cats

Journal of Small Animal Practice, EarlyView.
Objective It is currently unknown how often antibiotics (including metronidazole) are used for non‐antibacterial purposes in dogs and cats. This study looked to characterise the rationale for metronidazole prescription in these species. Methods Retrospective cohort study.
J. Ng, N. Steffensen, I. Battersby, J. S. Weese, D. Timofte, P. L. Toutain, J. L. Granick, J. Elliott, S. Choi, T. Sparks, S. Tavener, F. Allerton   +11 more
wiley   +1 more source

Spontaneous enteric nervous system activity generates contractile patterns prior to maturation of gastrointestinal motility

Neurogastroenterology &Motility, EarlyView.
Spontaneous neuronal network activity is critical for circuit maturation, yet whether this is a feature of enteric nervous system development has yet to be established. Here, we identify clustered ripples, a previously undescribed form of neurogenic gastrointestinal motility that shares many features with spontaneous neuronal networks in other systems.
Lori B. Dershowitz, Hassler Bueno Garcia, Andrew S. Perley, Todd P. Coleman, Julia A. Kaltschmidt   +4 more
wiley   +1 more source

Characterization of a Highly Toxigenic Clostridium tetani Strain from a Calf’s Castration Site

Veterinary Sciences
Background: This case report describes a calf that underwent castration at a Japanese livestock farm and subsequently died after developing clinical signs of tetanus, including muscle rigidity and difficulty standing.
Chie Shitada, Mayu Ohira, Mika Sekiguchi, Tomoko Koda, Motohide Takahashi, Makoto Kuroda   +5 more
doaj   +1 more source

Inhibitors of synaptic vesicle exocytosis reduce surface expression of postsynaptic glutamate receptors

Animal Cells and Systems, 2020
Bafilomycin A1, a vacuolar H+-ATPase inhibitor, and botulinum toxin B and tetanus toxin, both vesicle fusion inhibitors, are widely known exocytosis blockers that have been used to inhibit the presynaptic release of neurotransmitters.
Dong Ho Woo, Young-Na Hur, Minwoo Wendy Jang, C. Justin Lee, Mikyoung Park   +4 more
doaj   +1 more source

An Unusual Case of Tetanus Masquerading as an Acute Abdomen: A Case Report

Clinical Practice and Cases in Emergency Medicine, 2020
Introduction: Tetanus is an acute onset neurological disease that is often lethal. It has a high disease burden in low and middle-income countries. Tetanus is caused by a toxin made by spores of the bacterium Clostridium tetani, which are found in soil ...
Rahul Kumar Thakur, Rajshree Singh, Sabin Nepal, Prasanna Ghimire   +3 more
doaj   +1 more source

Fusion Pores as Regulators of Quantal Size and Cellular Physiology

BioEssays, Volume 47, Issue 11, November 2025.
During regulated exocytosis, membrane fusion regulatory factors act directly on SNAREs and membrane lipids to control fusion pore dynamics. This, in turn, leads to a differential amount of cargo release (referred to in this article as “quantal size”) across various cell types, thereby triggering distinct physiological cues.
Bhavya R. Bhaskar, Shahina Mazumdar, Sruthilaya Dayanandan, Debasis Das   +3 more
wiley   +1 more source

Systemic treatment of immune checkpoint inhibitor‐induced psoriasis: Inference‐based guidance

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 11, Page 1881-1894, November 2025.
When managing psoriasis, induced or exacerbated by ICI therapy for cancer, there are concerns regarding immunosuppression from systemic agents for the treatment of psoriasis and the potential impact on ICI efficacy. No direct, high‐level evidence exists to address these concerns.
Kim A. Papp, Luis Puig, Jennifer Beecker, Vinod Chandran, Joël Claveau, Javier Cortés, Jan Dutz, Noah I. Hornick, Rosalyn A. Juergens, Barbara Melosky, Anisha B. Patel, Maxwell B. Sauder, Sandeep Sehdev, Vincent Sibaud, Stephanie L. Snow   +14 more
wiley   +1 more source

Detección inmunoenzimática de la toxina de la bacteria Clostridium tetani: una alternativa a las pruebas biológicas con ratones

Revista de Biología Tropical, 2006
Immunoenzimatic detection of the Clostridium tetani bacterial toxin: an alternative to mice bioassays. Cell-free extracts from 20 strains of Clostridium tetani isolated from soil samples, were tested for tetanus toxin production using an enzyme ...
Fernando Chaves, Guillermo León, Francisco Hernández-Chavarría   +2 more
doaj  

Analyzing the Landscape of Botulinum Toxin Research: A Bibliometric Study of Publication Performance and Emerging Trends

Pain Practice, Volume 25, Issue 8, November 2025.
ABSTRACT Background This study aimed to conduct a comprehensive bibliometric analysis of the global scientific literature on botulinum toxin from 1991 to 2024, evaluating publication performance, citation impact, and emerging research foci. Methods Data were retrieved from the Science Citation Index Expanded (SCI‐EXPANDED) of the Web of Science Core ...
Yuh‐Shan Ho, Giancarlo De la Torre Canales, Nikolaos Christidis   +2 more
wiley   +1 more source

THE EFFECT OF KETAMINE AND ITS COMBINATION WITH INDOL-2-CARBOXYLIC ACID AND CAROVERINE ON SURVIVAL TIME OF MICE WITH EXPERIMENTAL TETANUS

Veterinaria, 2017
Tetanus, also known as lockjaw, is a very dangerous infectious acute, usually afebrile disease characterized by muscle spasms, affecting humans and various animal species. The causative agent of the disease is bacteria Clostridium tetani.
Indira Mujezinović, Ahmed Smajlović
doaj