Results 101 to 110 of about 7,006 (230)
Viruses, 2020 Tetherin is an interferon-inducible type II transmembrane glycoprotein which inhibits the release of viruses, including retroviruses, through a “physical tethering” model.
Bowen Bai +7 more
semanticscholar +1 more source
Journal of Extracellular Vesicles, Volume 14, Issue 8, August 2025.ABSTRACT In spite of the numerous clinical trials conducted on mesenchymal stromal cells and their extracellular vesicles (MSC‐EVs) across a wide range of diseases, the field faces challenges in reaching a consensus on crucial parameters such as source, marker definition, and culture conditions, adding to heterogeneous efficiencies. Nevertheless, there
Anton Selich +7 more
wiley +1 more source
A cell-based assay for CD63-containing extracellular vesicles [PDF]
, 2019 Extracellular vesicles (EVs) are thought to be important in cell-cell communication and have elicited extraordinary interest as potential biomarkers of disease. However, quantitative methods to enable elucidation of mechanisms underlying release are few.
Cashikar, Anil G, Hanson, Phyllis I
core +2 more sources
A single nucleotide polymorphism in tetherin promotes retrovirus restriction in vivo.
PLoS Pathogens, 2012 Tetherin is a membrane protein of unusual topology expressed from rodents to humans that accumulates enveloped virus particles on the surface of infected cells.
Bradley S Barrett +5 more
doaj +1 more source
The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu [PDF]
, 2009 Background The Human Immunodeficiency virus type 1 (HIV-1) Vpu protein enhances virus release from infected cells and induces proteasomal degradation of CD4.
Strebel Klaus +3 more
core +2 more sources
CAML does not modulate tetherin-mediated restriction of HIV-1 particle release.
PLoS ONE, 2010 BackgroundTetherin/BST-2 is a recently-identified potent restriction factor in human cells that restricts HIV particle release following particle formation and budding at the plasma membrane.
Mohammed S Ali +3 more
doaj +1 more source
Canine Influenza Virus is Mildly Restricted by Canine Tetherin Protein
Viruses, 2018 Tetherin (BST2/CD317/HM1.24) has emerged as a key host-cell ·defence molecule that acts by inhibiting the release and spread of diverse enveloped virions from infected cells.
Yun Zheng +8 more
doaj +1 more source
Journal of General Virology, 2020 Bone marrow stromal cell antigen-2 (BST-2), also known as tetherin, is an interferon-inducible membrane-associated protein. It effectively targets enveloped viruses at the release step of progeny viruses from host cells, thereby restricting the further ...
V. R. Zadeh +3 more
semanticscholar +1 more source
Tetherin does not significantly restrict dendritic cell-mediated HIV-1 transmission and its expression is upregulated by newly synthesized HIV-1 Nef [PDF]
, 2011 Background Dendritic cells (DCs) are among the first cells to encounter HIV-1 and play important roles in viral transmission and pathogenesis. Immature DCs allow productive HIV-1 replication and long-term viral dissemination.
Christopher M Coleman +2 more
core +2 more sources
Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion.
PLoS Pathogens, 2009 The recently identified restriction factor tetherin/BST-2/CD317 is an interferon-inducible trans-membrane protein that restricts HIV-1 particle release in the absence of the HIV-1 countermeasure viral protein U (Vpu). It is known that Tantalus monkey CV1
Ravindra K Gupta +5 more
doaj +1 more source