Results 91 to 100 of about 4,158 (155)

Lack of adaptation to human tetherin in HIV-1 Group O and P

Retrovirology, 2011
Background HIV-1 viruses are categorized into four distinct groups: M, N, O and P. Despite the same genomic organization, only the group M viruses are responsible for the world-wide pandemic of AIDS, suggesting better adaptation to human hosts ...
Haworth Kevin G, Exline Colin M, Lopez Lisa A, Yang Su Jung, Cannon Paula M   +4 more
doaj   +1 more source

Vpu induces proteasomal degradation of tetherin.

, 2013
(A) The MG132 proteasomal inhibitor impedes Vpu-mediated depletion of tetherin. 293T cells were transfected in duplicate with an HA-tetherin construct in the presence or absence of Vpu (with a molar ratio of 2∶1 in favor of Vpu), and were either left ...
Madeleine Zufferey (359889), Bastien Mangeat (25357), Jeremy Luban (126908), Martin Lehmann (45732), Gustavo Gers-Huber (158677), Vincent Piguet (192012)   +5 more
core   +1 more source

Antiviral activity of modified tetherin proteins in stable cell lines.

, 2013
(A) 293T cells stably expressing the modified tetherin proteins were analyzed by flow cytometry to determine the relative surface expression levels of tetherin, using a mouse anti-human tetherin antibody.
Siddarth Venkatesh (434865), Paul D. Bieniasz (215716)   +1 more
core   +1 more source

ISEV2025 Abstract Book

Journal of Extracellular Vesicles, Volume 14, Issue S1, October 2025.
wiley   +1 more source

NS1 does not antagonize tetherin.

, 2012
(A) Plasmids encoding the indicated proteins or empty plasmid were transfected into 293T cells and expression of tetherin and β-actin in cell lysates was determined by Western blot. Similar results were obtained in two separate experiments.
Annika Kühl (142444), Frank Kirchhoff (94157), Kerstin Gnirß (142409), Christina Ehrhardt (142426), Inga Nehlmeier (142415), Miriam Kiene (142432), Stephan Ludwig (142429), Anna-Sophie Moldenhauer (142435), Christina B. Karsten (142441), Stefan Pöhlmann (142445), Michael Winkler (119116), Stephanie Bertram (142403), Ali Gawanbacht (142419), Ulrike Goedecke (142438)   +13 more
core   +1 more source

Tetherin SNP Modeling

, 2019
Models, YASARA macros, and R scripts to analyze the single nucleotide polymorphisms (SNPs) that are found in the human genome (as of 08/2017) within the protein BST2/'Tetherin ...
Yasmeen Shorish, Christopher Berndsen, Camden Sutton, Ian R. Roy   +3 more
core   +1 more source

Tetherin antagonism by Nef depends on clathrin and dynamin 2.

, 2013
(A) Dominant-negative mutants of AP180 and Dyn2 were tested for disruption of Nef-mediated tetherin downregulation. 293T cells expressing HA-tagged rhesus tetherin were transfected with constructs expressing Nef, or empty vector, and constructs ...
Lawrence J. Stern (49046), Ruth Serra-Moreno (66346), Kerstin Zimmermann (432785), David T. Evans (140189)   +3 more
core   +1 more source

Replication-competent SIVcpz CRISPR screen identifies barriers to successful cross-species transmission. [PDF]

J Virol
Xie Q, Wang Q, Noettger S, Gosálbez G, Betzler AC, Volcic M, Kmiec D, Krebs S, Graf A, Gülensoy D, Weidinger G, Sparrer KMJ, Kirchhoff F.   +12 more
europepmc   +2 more sources

Correction: Glycosylation of canine tetherin is essential for its antiviral activity against H3N2 canine influenza virus. [PDF]

Front Vet Sci
Xu L, Hou Y, Liu S, Dai Y, Ou J, Ye S, Wang Z, Lu G, Li S.   +8 more
europepmc   +1 more source

Herpes simplex virus type-1 counteracts tetherin restriction via its virion host shutoff activity.:HSV-1 vhs is a tetherin antagonist

, 2013
The interferon inducible membrane protein tetherin (Bst-2/CD317) is an antiviral factor that inhibits enveloped virus release by cross-linking newly formed virus particles to the producing cell.
Banting, George, Crump, Colin, Mauricio, Rui, Zenner, Helen   +3 more
core