Results 111 to 120 of about 7,006 (230)
MedComm, Volume 6, Issue 7, July 2025.A brief view of possible etiologic events preceding the diagnosis of desiccation syndrome. ABSTRACT Sjögren's syndrome (SS) is a chronic autoimmune disorder characterized by T‐cell‐mediated B‐cell hyperactivity and cytokine production, clinically manifesting, dry mouth and eyes, accompanied by pain and fatigue.
Ying Hu +8 more
wiley +1 more source
Viral Membrane Channels: Role and Function in the Virus Life Cycle [PDF]
, 2015 10.3390/v7062771Viruses763261 ...
Aldabe +33 more
core +2 more sources
Biology of the Cell, Volume 117, Issue 7, July 2025.ABSTRACT The French Society for Cell Biology (SBCF) gathers all researchers working in the broad field of cell biology and is actively involved in several missions. Indeed, from communicating about the latest breakthroughs to announcing upcoming events, the SBCF also identifies and nurtures emerging talents while financially supporting young ...
Florence Niedergang +2 more
wiley +1 more source
Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques
PLoS Pathogens, 2020 Most simian immunodeficiency viruses use Nef to counteract the tetherin proteins of their nonhuman primate hosts. Nef also downmodulates cell-surface CD4 and MHC class I (MHC I) molecules and enhances viral infectivity by counteracting SERINC5.
Aidin Tavakoli-Tameh +8 more
semanticscholar +1 more source
Acute BVDV infection inhibits expression of interferon-stimulated genes during pregnancy recognition in bovine endometrium [PDF]
, 2017 Bovine viral diarrhea virus (BVDV) can evade host detection by downregulation of interferon signaling pathways. Infection of cows with noncytopathic (ncp) BVDV can cause early embryonic mortality. Upregulation of type I interferon stimulated genes (ISGs)
Abudureyimu, A +6 more
core +1 more source
Early Vertebrate Evolution of the Host Restriction Factor Tetherin [PDF]
Journal of Virology, 2015 ABSTRACT Tetherin is an interferon-inducible restriction factor targeting a broad range of enveloped viruses. Its antiviral activity depends on an unusual topology comprising an N-terminal transmembrane domain (TMD) followed by an extracellular coiled-coil region and a C-terminal glycosylphosphatidylinositol (GPI) anchor.
Elena Heusinger +3 more
openaire +2 more sources
The Roles of Exosomes in Anti‐Cancer Drugs
Cancer Medicine, Volume 14, Issue 9, May 2025.ABSTRACT Background Cancer is an escalating global health issue, with rising incidence rates annually. Chemotherapy, a primary cancer treatment, often exhibits low tumor‐targeting efficiency and severe side effects, limiting its effectiveness. Recent research indicates that exosomes, due to their immunogenicity and molecular delivery capabilities, hold
Panpan Feng +4 more
wiley +1 more source
Japanese encephalitis virus counteracts BST2 restriction via its envelope protein E. [PDF]
, 2017 It has been well documented that BST2 restricts the release of enveloped viruses by cross-linking newly produced virions to the cell membrane. However, it is less clear whether and how BST2 inhibits the release of enveloped viruses which bud via the ...
Fu, M +11 more
core +1 more source
Tetherin Antagonism by HIV-1 Group M Nef Proteins [PDF]
Journal of Virology, 2016 ABSTRACT Although Nef is the viral gene product used by most simian immunodeficiency viruses to overcome restriction by tetherin, this activity was acquired by the Vpu protein of HIV-1 group M due to the absence of sequences in human tetherin that confer susceptibility to Nef.
Juan F, Arias +7 more
openaire +2 more sources
PLoS ONE, 2012 In different primate lentiviruses, three proteins (Vpu, Env and Nef) have been shown to have anti-tetherin activities. SIVden is a primate lentivirus harbored by a Cercopithecus denti (C. denti) whose genome code for a Vpu gene.
Kristina Nikovics +5 more
doaj +1 more source