Results 71 to 80 of about 4,158 (155)
MedComm, Volume 6, Issue 7, July 2025.A brief view of possible etiologic events preceding the diagnosis of desiccation syndrome. ABSTRACT Sjögren's syndrome (SS) is a chronic autoimmune disorder characterized by T‐cell‐mediated B‐cell hyperactivity and cytokine production, clinically manifesting, dry mouth and eyes, accompanied by pain and fatigue.
Ying Hu +8 more
wiley +1 more source
Antagonism to human BST-2/tetherin by Sendai virus glycoproteins
, 2013 Tetherin is an interferon-inducible factor that restricts viral particle production. We show here that Sendai virus (SeV) induces a drastic decrease in tetherin levels in infected HeLa cells.
Rasga, Lara +2 more
core +1 more source
Biology of the Cell, Volume 117, Issue 7, July 2025.ABSTRACT The French Society for Cell Biology (SBCF) gathers all researchers working in the broad field of cell biology and is actively involved in several missions. Indeed, from communicating about the latest breakthroughs to announcing upcoming events, the SBCF also identifies and nurtures emerging talents while financially supporting young ...
Florence Niedergang +2 more
wiley +1 more source
, 2013 (A) Tetherin dimers might trap virions at the cell surface via the infiltration of one pair of membrane anchors into the viral envelope, while the other pair remains rooted in the infected cell membrane (axial configuration). ‘N’ and ‘C’ represent the N-
Siddarth Venkatesh (434865) +1 more
core +1 more source
The Roles of Exosomes in Anti‐Cancer Drugs
Cancer Medicine, Volume 14, Issue 9, May 2025.ABSTRACT Background Cancer is an escalating global health issue, with rising incidence rates annually. Chemotherapy, a primary cancer treatment, often exhibits low tumor‐targeting efficiency and severe side effects, limiting its effectiveness. Recent research indicates that exosomes, due to their immunogenicity and molecular delivery capabilities, hold
Panpan Feng +4 more
wiley +1 more source
Models depicting the effect of Vpu on Tetherin.
, 2013 (A) Model of how Vpu acts to remove Tetherin from site of virion assembly: In the absence of Vpu, Tetherin is able to tether the virions at the cell surface by the partitioning of membrane anchors between cell and virion membranes. In the presence of Vpu,
Trinity Zang (215703) +2 more
core +1 more source
Skin immunity and inflammation: cellular interactions and communication
Clinical &Translational Immunology, Volume 14, Issue 11, 2025.The skin is a vital organ that protects organisms from external insults, providing a barrier to the outside environment. This review provides a comprehensive overview of skin immunology and how skin immune homeostasis is maintained through cellular interactions and communication with an example of psoriasis.
Divyaa Narayanan +2 more
wiley +1 more source
CAML does not regulate cell surface levels of tetherin.
, 2013 A rabbit polyclonal anti-tetherin antibody was used to quantify tetherin on the cell surface of HeLa cells by flow cytometry. A) Unstained cell control (white) and tetherin surface staining (filled histogram) using primary rabbit anti-tetherin followed ...
Lingmei Ding (324106) +3 more
core +1 more source
PLoS Pathogens, 2012 The HIV-1 accessory protein Vpu counteracts tetherin (BST-2/CD317) by preventing its incorporation into virions, reducing its surface expression, and ultimately promoting its degradation.
Tonya Kueck, Stuart J D Neil
doaj +1 more source
Axially oriented tetherin homodimers directly trap virions.
, 2013 (A) Schematic representation of the protease-induced virion release assay. Modified tetherin dimers programmed with a protease cleavage site (scissors) are indicated as blue helices, while the WT tetherin dimers are indicated as red helices.
Siddarth Venkatesh (434865) +1 more
core +1 more source