Results 61 to 70 of about 42,760 (246)

Evaluation of Tetracyclines and Aminoglycosides consumption [PDF]

, 2016
Background: Tetracyclines and Aminoglycosides antimicrobials hold the last positions among all main antibiotic subgroups used yearly in hospitals. Nevertheless,without these medical remedies a qualified treatment of patients with different illnesses ...
Vovc, Liviu, Bernaz, Emilian P.
core   +1 more source

Asymmetric Single‐Atom Catalysts Govern Diffusible and Non‐Diffusible Non‐Radical Pathways for Selective Degradation of Antibiotic Resistance Genes

Advanced Science, EarlyView.
Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao, Jun Sun, Liang Zhang, Litao Lin, Zongfeng Wan, Bingcai Pan, Sheng Tang   +6 more
wiley   +1 more source

Ion Suppression Study for Tetracyclines in Feed [PDF]

, 2012
Ion suppression in analysis of tetracyclines in feed was studied. The conventional analysis consists of a liquid extraction followed by a clean-up step using solid phase extraction (SPE) technique and analysis of the tetracyclines by liquid ...
van Holthoon, F.L., Chico, J., Zuidema, T.   +2 more
core   +2 more sources

Health Risk Assessment of Tetracyclines Contamination in Soil-Cabbage (Brassica campestris L. ssp. chinensis) System

Agronomy
Tetracyclines (TCs) pollution in vegetable fields is a widely recognized concern, yet the health and ecological risks of TCs residues in the soil–cabbage food chain remain unclear.
Di Liu, Md. Jahidul Islam Shohag, Weiwen Qiu, Lingli Lu, Yuyan Wang, Xiaoe Yang   +5 more
doaj   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

The Development and Validation of an LC–Orbitrap–HRMS Method for the Analysis of Four Tetracyclines in Milk and Its Application to Determine Oxytetracycline Concentrations after Intramuscular Administration in Healthy Sarda Ewes and Those Naturally Infected with Streptococcus uberis

Separations
An LC–Orbitrap–HRMS method was developed and validated for the simultaneous determination of four tetracyclines—oxytetracycline (OTC), tetracycline (TC), doxycycline (DC), and chlortetracycline (CTC)—in milk.
Severyn Salis, Simone Dore, Nicola Rubattu, Vittoria D’Ascenzo, Francesca T. Cherchi, Stefano A. Lollai   +5 more
doaj   +1 more source

Modification‐Selective Inhibition of Succinate Dehydrogenase a Enables Tumor‐Restricted Mitochondrial Modulation

Advanced Science, EarlyView.
This work identifies acetylation‐dependent SDHA homeostasis as a determinant of tumor‐specific metabolic vulnerability. Guided by this mechanism, a modification‐selective inhibitor, ZPI‐3, selectively targets non‐acetylated SDHA, achieving tumor‐restricted SDH inhibition and effective bladder cancer control. Differential responses in clinical specimens
Kaikai Xu, Lulu Kong, Kebin Ye, Xinlu Bao, Haowen Liu, Ning Wang, Yongming Deng, Wei Wang, Shaohua Wei, Lin Zhou   +9 more
wiley   +1 more source

IFI27 and BAX are Essential for GSDME‐Mediated Myeloma Cell Pyroptosis

Advanced Science, EarlyView.
The proposed model of GSDME‐mediated MM cell pyroptosis modulated by IFI27 and BAX. IFI27 is downregulated in MM cells. Upon pyroptotic stimulation, such as DOX or ETO treatment, IFI27 is induced, therefore liberating BAX from BCL‐2 ❶. BAX is then recruited to mitochondria and forms homo‐oligomeric channels in OMM, therefore leading to cytochrome C ...
Yaoli Cui, Yuening Sun, Ziyang Liu, Xuntao Lai, Yunshu Zhao, Yan'er Wang, Yuanming He, Fang Xu, Du Feng, Longlong Liu, Zhenqian Huang, Lijie Xing, Xinliang Mao   +12 more
wiley   +1 more source

Screening of veterinary drug residues in milk from individual farms in Macedonia [PDF]

Macedonian Veterinary Review, 2011
A total of 497 raw milk samples collected at individual farms and collection tanks for milk from eight regions from Macedonia were examined for chloramphenicol, sulfonamides, quinolones and tetracyclines from October 2008 until April 2011.
Dimitrieska-Stojkovic Elizabeta, Hajrulai-Musliu Zehra, Stojanovska-Dimzoska Biljana, Sekulovski Pavle, Uzunov Risto   +4 more
doaj  

Bacteriostatic actions of some tetracyclines

, 1965
6-Demethyl-6-deoxytetracycline, 6-methyleneoxytetracycline, 7-chlortetracycline and 7-chlor-6-demethyltetracycline inhibit Aerobacter aerogenes in glucose-mineral salt media, by two modes of action, I and II, shown by tetracycline and oxytetracycline ...
J Benbough, G A Morrison
core   +1 more source