Results 61 to 70 of about 23,011 (262)
Mediators of leukocyte yctivation play a role in disseminated intravascular coagulation during orthotopic liver transplantation [PDF]
, 1994 Leukocytes play an important role in the development of disseminated intravascular coagulation (DIC). In the reperfusion phase of OLT a DIC-like situation has been described and has been held responsible for the high blood loss during this phase.
Bechstein, W. O. +6 more
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Microvascular Health as a Key Determinant of Organismal Aging
Advanced Science, Volume 12, Issue 47, December 18, 2025.Abstract Aging is a complex, multifaceted process affecting all organ systems, with vascular aging playing a central role in organismal health decline. Beyond its role in circulation, the vascular system acts as a dynamic interface between tissues, influencing countless physiological functions such as tissue regeneration and repair, immune responses ...
Mattia Cenciarini +4 more
wiley +1 more source
Epilepsia Open, Volume 10, Issue 6, Page 1966-1977, December 2025.Abstract Objective Understanding the role of plasma proteins in the pathophysiology of epilepsy is crucial for uncovering novel biological mechanisms and therapeutic targets. Mendelian randomization (MR) provides a valuable tool for dissecting potentially causal associations between circulating proteins and disease risk.
Jingfeng Fu, Wei Wu, Shangren Shen
wiley +1 more source
Pteridines, 2001 A pteridine glycoside in Synechococcus sp. PCC 7942, the structure of which had been tentatively identified as biopterin-glucoside, was isolated and characterized for its exact chemical structure by 2D-NMR spectroscopy. The determined structure is 1-0-(L-
Choi Yong Kee +3 more
doaj +1 more source
Oxygenase Domain of Drosophila melanogaster Nitric Oxide Synthase: Unique Kinetic Parameters Enable a More Efficient NO Release [PDF]
, 2007 Although nitric oxide (NO) is important for cell signaling and nonspecific immunity in the fruit fly Drosophila melanogaster, little is known about its single NO synthase (dNOS).
Bhattacharjee, A. +8 more
core +1 more source
Food Science &Nutrition, Volume 13, Issue 12, December 2025.Saturated fatty acids (SFA) primarily caused greater physical obesity, whereas Trans‐fatty (TFA) led to more pronounced metabolic damage. Both SFA and TFA diets induced obesity and anxiety‐like behaviors. 7‐Nitroindole (7‐NI) improved anxiety‐like behaviors in SFA‐fed mice but not in TFA‐fed.
Jin‐Cui Yang +4 more
wiley +1 more source
Pteridines, 1997 We examined the inhibitory effect of tetrahydrobiopterin (BPH4) on L-β-(3,4-dihydroxyphenyl)alanine (DOPA)-induced cytotoxicity in PC-12 cells. First in vitro inhibitory efficacy of BPH4 on lipid peroxidation induced by Fe3+-DOPA complex was confirmed by
Kojima Shuji +4 more
doaj +1 more source
Tetrahydrobiopterin Deficiency: From Phenotype to Genotype [PDF]
, 2017 As a result of the selective screening worldwide during the last 18 years, approximately 250 patients with tetrahydrobiopterin deficiency were discovered.
Blau, Nenad +3 more
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Insights from a Murine Aortic Transplantation Model [PDF]
, 2016 Transplant vasculopathy (TV) represents a major obstacle to long-term graft survival and correlates with severity of ischemia reperfusion injury (IRI). Donor administration of the nitric oxide synthases (NOS) co-factor tetrahydrobiopterin has been shown ...
Bernhard, David +11 more
core +1 more source
Food Science &Nutrition, Volume 13, Issue 12, December 2025.BPA exposure in rats and HUVECs impaired aortic contractility, increased lipid peroxidation, ROS, NO, VCAM‑1, and p‑eNOS, and blunted relaxant responses. Co‑treatment with NSO or TQ restored KCl/PE‑induced contractions, enhanced ACh‑ and SNP‑mediated vasorelaxation, and lowered oxidative/nitrosative stress and adhesion molecule expression.
Masoumeh Fadishei +6 more
wiley +1 more source