Results 181 to 190 of about 4,966 (204)

Tetramethylpyrazine : a Bacillus subtilis Growth Factor

Nature, 1962
WE have found1 that a strain of Bacillus sublilis produced tetramethylpyrazine in synthesized media containing asparagine as nitrogen source.
T, KOSUGE, H, KAMIYA
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Antiplatelet structure-activity relationship of tetramethylpyrazine

Life Sciences, 1994
Tetramethylpyrazine (TMPZ) is an active component of certain plants previously found to have inhibitory effects on platelet function using both in vivo and in vitro assays(1). In this study, we examined the antiplatelet activity of structural analogues of TMPZ in order to assess structural requirements for activity.
S Y, Liu, D M, Sylvester
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Screening and identification of high yield tetramethylpyrazine strains in Nongxiangxing liquor Daqu and study on the mechanism of tetramethylpyrazine production

Journal of the Science of Food and Agriculture, 2023
AbstractBACKGROUNDThere are few reports on the breeding of high‐yielding tetramethylpyrazine (TTMP) strains in strong‐flavor Daqu. In addition, studies on the mechanism of TTMP production in strains are mostly based on common physiological and biochemical indicators, and there is no report on RNA level.
Yanbo Liu, Mengke Li, Xinfeng Hong, Haideng Li, Runna Huang, Suna Han, Jianguang Hou, Chunmei Pan   +7 more
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Paramagnetic resonance of phosphorescent tetramethylpyrazine

Molecular Physics, 1975
Electron paramagnetic resonance spectra have been obtained of tetramethylpyrazine in its lowest (ππ*) triplet state in several rigid matrices. Some unusual observations were made : 1. (1) In a durene crystal host the in-plane zero-field principal axes are not parallel to the molecular symmetry axes. 2.
M.S. de Groot, I.A.M. Hesselmann, F.J. Reinders, J.H. van der Waals   +3 more
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Tetramethylpyrazine Attenuates Radiation-Induced Ototoxicity in a Rat Model

Audiology and Neurotology, 2023
<b><i>Introduction:</i></b> Tetramethylpyrazine (TMP) is a chemical compound, which has been shown to possess numerous biological features such as anticoagulation, inhibition of platelet aggregation, anti-inflammation, capillary dilatation, improvement in microcirculation, and protection against reactive oxygen radicals. The aim
Mustafa Sahin, Altan Kaya, Aynur Aytekin, Ebru Akay, Ibrahim Ozcan   +4 more
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Tetramethylpyrazine reduces ischemic brain injury in rats

Neuroscience Letters, 2004
Tetramethylpyrazine (TMP), which is widely used in the treatment of ischemic stroke by Chinese herbalists, is one of the most important active ingredients of the traditional Chinese herbal medicine, Ligusticum wallichii Franchat (Chung Xiong). However, the mechanism by which TMP protects the brain is still not clear. We examined neuroprotective effects
Su-Lan, Liao, Tsung-Kuei, Kao, Wen-Yin, Chen, Yu-Sheng, Lin, Shih-Yun, Chen, Shue-Ling, Raung, Ching-Wen, Wu, Hsi-Chi, Lu, Chun-Jung, Chen   +8 more
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Physicochemical characterization and percutaneous delivery of 2,3,5,6-tetramethylpyrazine

International Journal of Pharmaceutics, 2003
The objective of this work is to investigate the percutaneous permeability of 2,3,5,6-tetramethylpyrazine (TMP), an active ingredient originally isolated from Ligusticum wallichii Franch. Certain physicochemical properties of TMP, including its partition coefficient and pH-solubility profile, were studied.
Xiaohong, Qi, Chrisita, Ackermann, Duxin, Sun, Minli, Sheng, Huimin, Hou   +4 more
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Tetramethylpyrazine ameliorates hepatic fibrosis through autophagy-mediated inflammation

Biochemistry and Cell Biology, 2020
Background: Imbalanced immune response and hepatic fibrosis are key factors related to the progression of chronic liver diseases. Tetramethylpyrazine (TMP), a natural alkaloid, has been widely used for treating liver injury. In this study, we explored the effect of TMP on hepatic fibrosis and the related mechanisms regulating autophagy. Methods: A rat
Zhigao, Hu, Huizhao, Su, Yonglian, Zeng, Chengjie, Lin, Zhenya, Guo, Fudi, Zhong, Keqing, Jiang, Guandou, Yuan, Songqing, He   +8 more
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Tetramethylpyrazine Improves Postoperative Tissue Adhesion: A Drug Repurposing

Chinese Journal of Integrative Medicine, 2019
Plants are known to possess plenty of pharmacological activities as a result of various phytoconstituents. Tetramethylpyrazine (TMP), one of the most widely used medicinal compound isolated from traditional Chinese herb, is usually employed for anti-oxidation, anti-inflammation, anti-platelet aggregation, anti-lipid, anti-fibrosis, as well as ...
Shuai, Yan, Yin-Zi, Yue, Yang, Zong, Li, Zeng   +3 more
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GC–FID determination of tetramethylpyrazine and acetoin in vinegars and quantifying the dependence of tetramethylpyrazine on acetoin and ammonium

Food Chemistry, 2018
2,3,5,6-Tetramethylpyrazine (TMP) is an important health functional composition in vinegars, but there are controversial viewpoints about its formation mechanism and scarce relevant records on TMP content enhancement in vinegar products. In this study, a simple and accurate solvent extraction coupled with GC-FID method was developed for the ...
Zijun Xiao, Ling Zhao, Li Tian, Linhui Wang, Jing-yi Zhao   +4 more
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