Results 71 to 80 of about 3,816 (178)

Luzhou‐Flavor Baijiu Alleviates Stress‐Related Depressive‐Like Changes by NMDAR‐NO‐sGC‐cGMP Pathway

Food Safety and Health, Volume 4, Issue 2, Page 475-487, April 2026.
Luzhou‐flavor baijiu (LFB) alleviates depressive‐like phenotypes in CRS‐induced mice and protects HT22 cells from corticosterone damage, with mechanisms linked to suppressing the NMDAR‐nNOS/iNOS‐NO‐sGC‐cGMP pathway. ABSTRACT Moderate alcohol consumption has been suggested to alleviate anxiety and depression; however, it remains unclear whether Luzhou ...
Li Xiong, Yongkang Wu, Zhangjun Huang, Songtao Wang, Ping Yang, Caihong Shen, Huan Guo, Yue Xiao, Qian Bu, Hong Gao, Yina Huang   +10 more
wiley   +1 more source

Tetramethylpyrazine Antagonizes the Subchronic Cadmium Exposure-Induced Oxidative Damage in Mouse Livers via the Nrf2/HO-1 Pathway

Molecules
Hepatic oxidative stress is an important mechanism of Cd-induced hepatotoxicity, and it is ameliorated by TMP. However, this underlying mechanism remains to be elucidated.
Xue Hu, Siqi Zhao, Ziming Guo, Yiling Zhu, Shuai Zhang, Danqin Li, Gang Shu   +6 more
doaj   +1 more source

Advances in Hydrogel Tissue Engineering for Spinal Cord Injury Repair

Smart Medicine, Volume 5, Issue 2, April 2026.
This review systematically introduces the pathological process of spinal cord injury (SCI) and the applications and biological roles of hydrogels in SCI repair. Emerging 4D printing and gene therapy strategies are also discussed. ABSTRACT Spinal cord injury (SCI), which is a severe complication of spinal fractures, often causes the dysfunction of the ...
Ruixing Shui, Fan Ding, Dapeng Li, Guoqing Pan   +3 more
wiley   +1 more source

Tetramethylpyrazine improved the survival of multiterritory perforator flaps by inducing angiogenesis and suppressing apoptosis via the Akt/Nrf2 pathway

, 2019
LiMing Qing,1,2 PanFeng Wu,1 ZhengBing Zhou,1 Fang Yu,1 JuYu Tang11Department of Orthopedics, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 2Department of Neurosurgery, Maryland University of Medicine ...
Tang J, Wu P, Yu F, Qing L, Zhou Z
core  

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

VIEW, Volume 7, Issue 2, April 2026.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu, Linlin Cao, Chenhuan Ding, Chen Wang, Yi Lai, Dan Ru, He Li, Wei Xu   +7 more
wiley   +1 more source

การแยกแบคทีเรียแลคติกจากอาหารหมักที่มีศักยภาพในการผลิต tetramethylpyrazine

, 2008
คณะผู้วิจัยทำการแยกแบคทีเรียแลคติกจำนวน 43 ไอโซเลท จากอาหารหมัก 14 ชนิด แล้วนำเชื้อที่ได้มาทดสอบศักยภาพในการเป็นผู้ผลิต tetramethylpyrazine (TMP) โดยทดสอบการสร้าง acetoin และความสามารถในการใช้อาร์จินีนเป็นแหล่งพลังงาน ซึ่งจากการทดสอบพบว่ามีแบคทีเรียจำนวน
อังประภาพรชัย, ประวัติ, สงบพันธ์, นัทธ์หทัย, โสภา, ภัทราวุธ   +2 more
core  

DataSheet1_Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis.docx

, 2023
The pathophysiology of Alzheimer’s disease (AD) is multifactorial with characteristic extracellular accumulation of amyloid-beta (Aβ) and intraneuronal aggregation of hyperphosphorylated tau in the brain. Development of disease-modifying treatment for AD
Yuqiang Wang (418189), Yingying Liu (360782), Xinhua Zhou (563087), Xifei Yang (323243), Maggie Pui Man Hoi (10813447), Qinghua Hou (5301989), Kaipeng Huang (310178), Zaijun Zhang (305835)   +7 more
core   +1 more source

Tetramethylpyrazine attenuated bupivacaine-induced neurotoxicity in SH-SY5Y cells through regulating apoptosis, autophagy and oxidative damage

, 2019
Shouliang Wang,1 Bin Xia,1 Zonglei Qiao,2 Lian Duan,3 Gongming Wang,1 Wenjun Meng,1 Zhifei Liu,1 Yu Wang,1 Mengyuan Zhang11Department of Anesthesiology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, People&rsquo ...
Duan L, Liu Z, Wang S, Wang G, Zhang M, Xia B, Wang Y, Qiao Z, Meng W   +8 more
core  

Tetramethylpyrazine from

Natural Product Communications, 2015
For the first time, the bioactive compound tetramethylpyrazine (TMP) was isolated and identified from the culture of Pleurotus geesteranus Singer. Its identification was confirmed unambiguously by identical retention time and mass spectrum to those of a ...
Hengsheng Shen, Huaizhi Liu, Junchen Chen, Suqin Shao, Honghui Zhu, Rong Tsao, Ting Zhou   +6 more
doaj   +1 more source

Microneedle-Assisted Percutaneous Delivery of a Tetramethylpyrazine-Loaded Microemulsion

Molecules, 2017
This study examined the efficacy of the percutaneous delivery of a tetramethylpyrazine-loaded microemulsion (TMP-ME) on skin pretreated with microneedles (MN).
Qiang Zu, Yanyan Yu, Xiaolin Bi, Ren Zhang, Liuqing Di   +4 more
doaj   +1 more source