Results 81 to 90 of about 3,816 (178)

Image1_Inconsistent Time-Dependent Effects of Tetramethylpyrazine on Primary Neurological Disorders and Psychiatric Comorbidities.TIF

, 2021
The aim of this study was to investigate the time dependent effects of tetramethylpyrazine (TMP, main activity compound of Ligusticum chuanxiong Hort) on two neurological disorders and their neuropsychiatric comorbidities. 6 Hz corneal rapid kindling was
Yue-Peng Jiang (11304456), Wei-Dong Lai (11304459), Zheng-Hao Xu (423363), Jie Yu (150626), Yan Jin (143500), Jie Bao (404268), Song Wang (144220), Cheng-Ping Wen (11304462)   +7 more
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Inclusion of tetramethylpyrazine in channels of the organic zeolite 2,4,6-tris(4-bromophenoxy)-1,3,5-triazine [PDF]

, 2018
2,4,6-tris(4-bromophenoxy)-1,3,5-triazine (BrPOT) features a channel size (11-12Å) allowing the inclusion of large guest molecules such as tetramethylpyrazine (TMPZ). TMPZ forms π-stacks (d: 3.5Å) along channels of BrPOT and shows rotational disorder for
Hulliger, Jürg, Bonin, Michel, Couderc, Gaëtan, Labat, Gaël, Berger, Ricarda   +4 more
core  

Selective suppression of the JNK-MMP2/9 signal pathway by tetramethylpyrazine attenuates neuropathic pain in rats

, 2017
Background Activated astrocytes release matrix metalloproteinase-2/9 (MMP-2/9) to induce central sensitization and maintain neuropathic pain. However, the mechanisms involved in the activation of MMP-2/9 on astrocytes during pain remain poorly understood.
Cai-Long Pan, Wen-Tao Liu, Lei Liu, Jun-Wei Qu, Chao-Yu Wang, Bing-Qian Liu, Yang Yang, Yuan Han, Liang Hu, Lai Jiang   +9 more
core   +1 more source

Tetramethylpyrazine attenuates spinal cord ischemic injury due to aortic cross-clamping in rabbits [PDF]

, 2002
Background Lower limb paralysis occurs in 11% of patients after surgical procedure of thoracic or thoracoabdominal aneurysms and is an unpredictable and distressful complication. The aim of this study was to investigate the effects of tetramethylpyrazine
Hanfei Sang, Dong Hailong, Sang Hanfei, Chen Shaoyang, Zhihong Lu, Hailong Dong, Wang Qiang, Shaoyang Chen, Zhu Zhenhua, Lize Xiong, Zhenhua Zhu, Xiong Lize, Qiang Wang, Lu Zhihong   +13 more
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The mechanism of Laceyella sacchari FBKL4.010 produced tetramethylpyrazine in the liquid fermentation by comparative transcriptomic techniques

Frontiers in Microbiology
Tetramethylpyrazine (TTMP) is considered a crucial flavor component in Moutai-flavored liquor. Laceyeella sacchari FBKL4.010 (L. sacchari) is the dominant species found in Moutai-flavor Daqu, and this study aims to determine the mechanism by which L ...
Xiaodan Wang, Xiaodan Wang, Wu Huang, Wu Huang, Jin Huang, Xiaoye Luo, Xiaoye Luo, Mingbo Nie, Tao Jiang, Shidong Ban, Pei Li, Pei Li   +11 more
doaj   +1 more source

Intra-articular delivery of tetramethylpyrazine microspheres with enhanced articular cavity retention for treating osteoarthritis

, 2018
Tetramethylpyrazine (TMP) is a traditional Chinese herbal medicine with strong anti-inflammatory and cartilage protection activities, and thus a promising candidate for treating osteoarthritis.
Xiuping Zhang, Yang Shi, Guihua Huang, Zhenlei Yang, Zhiyue Zhang   +4 more
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Screening and identification of a bacterial strain for the production of tetramethylpyrazine through solid-state fermentation and determination of its high-yield mechanism

Journal of Taibah University for Science
In this study, a strain producing a high yield (1.72 mg·g–1) of tetramethylpyrazine (TTMP) was screened under solid-state conditions from high-temperature Daqu and was identified as Bacillus velezensis using 16S rDNA molecular technology.
Wanwan Zhuansun, Jun Xu, Zhiqiang Li, Hengzhao Liu, Yin Zhao, Lulu Chen, Shufang Shan, Xin Zeng, Binyue Xin, Huawei Zeng, Qinxiang Xu   +10 more
doaj   +1 more source

From a traditional medicine monomer to a modern neurotherapeutic scaffold: a review of SAR-Driven tetramethylpyrazine derivatives for cerebrovascular and cognitive health

Frontiers in Pharmacology
Tetramethylpyrazine (TMP), a bioactive alkaloid isolated from the traditional Chinese medicine Ligusticum wallichii (Chuanxiong), has gained significant attention for its therapeutic potential in cerebrovascular diseases and cognitive impairment, mainly ...
Xiaodi Wang, Muhan Cao, Yi Xu, Xifei Yang, Qinghua Hou   +4 more
doaj   +1 more source

Efficacy and neuroprotective effects of tetramethylpyrazine in animal models of spinal cord injury: a systematic review, meta-analysis, and exploratory machine-learning study

Frontiers in Pharmacology
BackgroundSpinal cord injury (SCI) is a severe neurological disorder characterized by persistent motor dysfunction and complex secondary injury processes. Tetramethylpyrazine (TMP) has shown potential neuroprotective effects in experimental SCI; however,
Shaocong Li, Shaocong Li, Sichong Qiu, Qiqi Tang, Qiqi Tang, Junxiao Ren, Junxiao Ren, Zewei Zhao, Zewei Zhao, Xiangjin Wang, Xiangjin Wang, Xiaohong Fan, Xiaohong Fan   +12 more
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Sustainable production of 2,3,5,6-Tetramethylpyrazine at high titer in engineered Corynebacterium glutamicum [PDF]

The industrial amino acid production workhorse, Corynebacterium glutamicum naturally produces low levels of 2,3,5,6-tetramethylpyrazine (TMP), a valuable flavor, fragrance, and commodity chemical.
Banerjee, Deepanwita, Simmons, Blake A, Pidatala, Venkataramana R, Eudes, Aymerick, Srinivasan, Aparajitha, Oka, Asun, Chen-Xiao, Kevin, Eng, Thomas, Mukhopadhyay, Aindrila   +8 more
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