Results 41 to 50 of about 3,124 (157)

Perspectives on the utility and interest in a point-of-care urine tenofovir test for adherence to HIV pre-exposure prophylaxis and antiretroviral therapy: an exploratory qualitative assessment among U.S. clients and providers

AIDS Research and Therapy, 2020
Background Real-time, objective measures of adherence to antiretroviral therapy (ART) and pre-exposure prophylaxis (PrEP) are needed to better assess adherence levels and to expedite clinical response for those with suboptimal adherence.
Ashley R. Bardon, Jane M. Simoni, Leif M. Layman, Joanne D. Stekler, Paul K. Drain   +4 more
doaj   +1 more source

İşletmelerin Malmquist-TFV Endeksi İle Verimliliklerinin Analizi: Tekstil Sanayi Örneği

Selçuk Üniversitesi Sosyal Bilimler Meslek Yüksekokulu Dergisi, 2018
ÖZ       Günümüzde işletmelerin rekabetçi üstünlük ve ortalamanın üzerinde getiri elde etmelerinde göstermiş oldukları performans, önem arz etmektedir. İşletmelerin performansını belirleyen en önemli ölçütlerden birisi verimlilik artışıdır. Verimlilik artışıyla işletmelerin amaçlarına ulaşabilmeleri ve kârlılık hedeflerini tutturabilmeleri mümkün hale
GELMEZ, Emel, GÖRAL, Ramazan, ÇAĞLIYAN, Vural   +2 more
openaire   +4 more sources

Vaginal microbiota and mucosal pharmacokinetics of tenofovir in healthy women using tenofovir and tenofovir/levonorgestrel vaginal rings.

PLoS ONE, 2019
Recent data support that the vaginal microbiota may alter mucosal pharmacokinetics (PK) of topically delivered microbicides. Our team developed an intravaginal ring (IVR) that delivers tenofovir (TFV) (8-10 mg/day) alone or with levonorgestrel (LNG) (20 ...
Andrea Ries Thurman, Jill L Schwartz, Jacques Ravel, Pawel Gajer, Mark A Marzinke, Nazita Yousefieh, Sharon M Anderson, Gustavo F Doncel   +7 more
doaj   +1 more source

Probenecid‐Boosted Tenofovir: A Physiologically‐Based Pharmacokinetic Model‐Informed Strategy for On‐Demand HIV Preexposure Prophylaxis

CPT: Pharmacometrics & Systems Pharmacology, 2020
Multiple doses of tenofovir disoproxil fumarate (TDF) together with emtricitabine is effective for HIV preexposure prophylaxis (PrEP). TDF is converted to tenofovir (TFV) in circulation, which is subsequently cleared via tubular secretion by organic ion ...
Stephanie N. Liu, Zeruesenay Desta, Brandon T. Gufford   +2 more
doaj   +1 more source

Urine Assay to Measure Tenofovir Concentrations in Patients Taking Tenofovir Alafenamide

Frontiers in Pharmacology, 2020
Background: HIV pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine is effective when taken daily. Previously, we developed a urine assay capable of detecting the prodrug tenofovir (TFV) in patients taking tenofovir disoproxil fumarate (TDF ...
Linden Lalley-Chareczko, Emily Hiserodt, Ganesh Moorthy, Athena Zuppa, Karam Mounzer, Helen Koenig, Helen Koenig   +6 more
doaj   +1 more source

Gender Lens Equity Funds: A Methodological Breadth–Accountability Depth Framework and Observed Outcomes

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Despite rapid growth in gender lens investing (GLI), substantial variation remains in how gender lens equity funds (GLEFs) integrate gender equality criteria into investment strategies. We map a universe of 43 GLEFs and develop a framework capturing gender equality screening breadth and accountability depth (fund‐level disclosure and ...
Freyja Vilborg Thorarinsdottir, Ásta Dís Óladóttir, Gary L. Darmstadt, Sigríður Benediktsdóttir   +3 more
wiley   +1 more source

Karadeniz Bölgesinde Bulunan İllerin Eğitim Etkinliklerinin Ortaöğretim Düzeyinde İncelenmesi: Malmquıst-TFV Endeksi Uygulaması

Anadolu Üniversitesi Sosyal Bilimler Dergisi, 2016
 Hızla gelişen rekabet ortamı içerisinde toplumların gelişimi, eğitimde etkinlik ve verimliliği arttırmalarıyla mümkündür. Bu kapsamda özellikle ortaöğretim, bir ülkenin kalkınmasında önemli rol oynamaktadır. Bu çalışmada Karadeniz Bölgesi’nde bulunan 18 ilin 2007-2011 dönemindeki ortaöğretim düzeyinde eğitim performanslarında meydana ...
AR, Doç. Dr. İlker Murat, OFLUOĞLU, Öğr. Grv. Aylin, BAKİ, Prof. Dr. Birdoğan   +2 more
openaire   +5 more sources

Steady-state pharmacokinetics of plasma tenofovir alafenamide (TAF), tenofovir (TFV) and emtricitabine (FTC), and intracellular TFV-diphosphate and FTC-triphosphate in HIV-1 infected old Japanese patients treated with bictegravir/FTC/TAF

Global Health & Medicine, 2023
Emtricitabine (FTC) plus tenofovir alafenamide (TAF) has demonstrated efficacy and safety for pre-exposure prophylaxis (PrEP) to prevent HIV-1 infection. We measured the plasma PK of FTC, tenofovir (TFV), and TAF in a steady-state pharmacokinetic (PK) study of bictegravir/FTC/TAF in HIV-1-infected patients.
Hieu Trung, Tran, Kiyoto, Tsuchiya, Akira, Kawashima, Koji, Watanabe, Yoshiharu, Hayashi, Shoraku, Ryu, Akinobu, Hamada, Hiroyuki, Gatanaga, Shinichi, Oka   +8 more
openaire   +2 more sources

Quantification of Antiviral Drug Tenofovir (TFV) by Surface-Enhanced Raman Spectroscopy (SERS) Using Cumulative Distribution Functions (CDFs)

ACS Omega, 2023
Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive spectroscopic technique that generates signal-enhanced fingerprint vibrational spectra of small molecules. However, without rigorous control of SERS substrate active sites, geometry, surface area, or surface functionality, SERS is notoriously irreproducible, complicating the consistent ...
Marguerite R. Butler, Jana Hrncirova, Meredith Clark, Sucharita Dutta, John B. Cooper   +4 more
openaire   +4 more sources

Social Representations of Bedside Milk Expression Among Mothers of Preterm Newborns in Neonatal Intensive Care Units

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To understand the social representations of bedside milk expression (BME) among mothers of preterm newborns in neonatal intensive care units (NICUs). Design Qualitative descriptive study. Methods The study was conducted from July to August 2024 in two NICUs of a referral maternity hospital in Fortaleza, Brazil.
Ana Karen de Sousa Alves, Ana Paula Melo Façanha, Elaine Meireles Castro, Keline Soraya Santana Nobre, Flávia Vasconcelos Teixeira, Maria Milena Farias de Souza Castro, José Mateus Pires, Victórya Suéllen Maciel Abreu, Priscila de Souza Aquino   +8 more
wiley   +1 more source