Results 51 to 60 of about 3,124 (157)

Türkiye Tarım Sektöründe Toplam Faktör Verimliliği (TFV): 1961-2021 Döneminin Malmquist TFV Endeksiyle Analizi

Verimlilik Dergisi
Amaç: Bu çalışma, Türkiye tarım sektörünün 1961–2021 dönemindeki toplam faktör verimliliğini (TFV) ölçmek, teknik etkinlik değişimi (TEC) ile teknolojik etkinlik değişimi (TC) gibi TFV bileşenlerinin zaman içinde gösterdiği performansı etkileyen faktörleri analiz etmek amacıyla gerçekleştirilmiştir.
Mehmet Ali Cevheri, Nihat Küçük
openaire   +1 more source

Veri Zarflama Analizi (VZA) ve Malmquist Toplam Faktör Verimliliği (TFV): Konaklama İşletmelerinde Bir Uygulama [PDF]

Ege Akademik Bakis (Ege Academic Review), 2012
Global dunyada yogun rekabet kendini gostermektedir. Bu surecte hemen hemen butun ekonomilerin, kurumlarin, toplumlarin ve bireylerin yuksek rekabet kulturune uygun davranmasi zorunlu olmaktadir. Konaklama isletmelerinin etkinligi ve verimliligi ise yogun rekabet ortaminda cok daha onemli hale gelmektedir.
openaire   +3 more sources

Effect of Liraglutide on Intermittent Hypoxia‐Induced Metabolic Dysfunction: From Bench to Bedside

Journal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Intermittent hypoxia (IH)‐mediated adipose tissue inflammation with M1 macrophage polarisation plays a key role in the pathogenesis of metabolic diseases in obstructive sleep apnoea (OSA). Effective treatment strategies are so far lacking.
Cliona O'Donnell, Ailbhe King, Guillaume Vial, Emily O'Neill, Shane Crilly, Jonathan D. Dodd, David J. Murphy, Elise Belaidi, Jean‐Louis Pepin, Claire Arnaud, Donal O'Shea, Silke Ryan   +11 more
wiley   +1 more source

Detection and quantification of antiviral drug tenofovir using silver nanoparticles and surface enhanced Raman spectroscopy (SERS) with spatially resolved hotspot selection

Frontiers in Nanotechnology, 2023
This study introduces a convenient and ultra-sensitive method of detection and quantification of the antiviral drug, tenofovir (TFV), by surface-enhanced Raman spectroscopy (SERS).
Marguerite R. Butler, Jana Hrncirova, Jana Hrncirova, Terry A. Jacot, Sucharita Dutta, Meredith R. Clark, Gustavo F. Doncel, John B. Cooper   +7 more
doaj   +1 more source

Chemical Profile, Anti‐Inflammatory, and Antioxidant Potential of Hydroalcoholic Extracts and Fractions From Baccharis glaziovii Baker (Asteraceae)

Chemistry &Biodiversity, Volume 23, Issue 3, March 2026.
Image adapted from Jasinski et al. [79], Revista Brasileira de Farmacognosia 24, no. 6: 609–616. Reproduced under the terms of the CC BY license. Copyright 2014 by the authors; published by Elsevier. ABSTRACT Baccharis glaziovii Baker, known as carqueja‐arbustinho, is a native Brazilian plant characterized by its three‐winged stems.
Fabio Vidal Tananta, Vanessa Cristina Godoy Jasinski, Marcos José Salvador, Josiane de Fátima Gáspari Dias, Francinete Ramos Campos   +4 more
wiley   +1 more source

Viability of primary osteoblasts after treatment with tenofovir alafenamide: Lack of cytotoxicity at clinically relevant drug concentrations. [PDF]

PLoS ONE, 2017
Tenofovir alafenamide (TAF) is a phosphonoamidate prodrug of the nucleotide HIV reverse transcriptase inhibitor tenofovir (TFV). TAF is approved for the treatment of HIV-1 infection as part of the single-tablet regimen containing elvitegravir, cobicistat,
Christian Callebaut, Yang Liu, Darius Babusis, Adrian Ray, Michael Miller, Kathryn Kitrinos   +5 more
doaj   +1 more source

Strong Correlation Between Concentrations of Tenofovir (TFV) Emtricitabine (FTC) in Hair and TFV Diphosphate and FTC Triphosphate in Dried Blood Spots in the iPrEx Open Label Extension: Implications for Pre-exposure Prophylaxis Adherence Monitoring [PDF]

Journal of Infectious Diseases, 2015
Self-reported adherence to pre-exposure prophylaxis (PrEP) has limitations, raising interest in pharmacologic monitoring. Drug concentrations in hair and dried blood spots (DBS) are used to assess long-term-exposure; hair shipment/storage occurs at room temperature.
Gandhi, Monica, Glidden, David V, Liu, Albert, Anderson, Peter L, Horng, Howard, Defechereux, Patricia, Guanira, Juan V, Grinsztejn, Beatriz, Chariyalertsak, Suwat, Bekker, Linda-Gail, Grant, Robert M, iPrEx Study Team   +11 more
openaire   +4 more sources

Quantitative Systems Pharmacology Models of Anti‐Amyloid Treatments for Alzheimer's Disease: A Systematic Review

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 3, March 2026.
ABSTRACT Quantitative systems pharmacology (QSP) models have emerged as useful tools for evaluating the efficacy of Alzheimer's disease (AD) therapies. Bringing together a clinical focus with the mechanistic detail of systems biology, QSP models are well suited to the complexity of AD and have been used to predict treatment outcomes and support ...
Lara Herriott, Mark Coles, Nicolas Fournier, Eamonn Gaffney, Jonathan Wagg   +4 more
wiley   +1 more source

Hypo-osmolar rectal douche tenofovir formulation prevents simian/human immunodeficiency virus acquisition in macaques

JCI Insight, 2022
In spite of the rollout of oral pre-exposure prophylaxis (PrEP), the rate of new HIV infections remains a major health crisis. In the United States, new infections occur predominantly in men having sex with men (MSM) in rural settings where access to ...
Peng Xiao, Sanjeev Gumber, Mark A. Marzinke, Thuy Hoang, Rohan Myers, Abhijit A. Date, Justin Hanes, Laura M. Ensign, Lin Wang, Lisa C. Rohan, Richard Cone, Edward J. Fuchs, Craig W. Hendrix, Francois Villinger   +13 more
doaj   +1 more source

A multi-compartment, single and multiple dose pharmacokinetic study of the vaginal candidate microbicide 1% tenofovir gel. [PDF]

PLoS ONE, 2011
Tenofovir (TFV) gel is being evaluated as a microbicide with pericoital and daily regimens. To inhibit viral replication locally, an adequate concentration in the genital tract is critical.Forty-nine participants entered a two-phase study: single-dose ...
Jill L Schwartz, Wes Rountree, Angela D M Kashuba, Vivian Brache, Mitchell D Creinin, Alfred Poindexter, Brian P Kearney   +6 more
doaj   +1 more source