Results 1 to 10 of about 286,627 (148)
Unraveling the influence of TGF-β rs9282871 and miRNA let-7c relative expression on TGF-β production in hepatocellular carcinoma patients [PDF]
Journal of Genetic Engineering and BiotechnologyHepatocellular carcinoma (HCC) is ranked globally as the second most common cancer-related death. Transforming growth factor beta (TGF-β) plays a dual role in HCC.
Sally Farouk +3 more
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Latent-TGF-β has a domain swapped architecture [PDF]
Nature CommunicationsThe multifunctional cytokine TGF-β is a dimeric protein produced within a latent complex (L-TGF-β). Latency is maintained by disulfide linked homodimeric prodomains forming a ring encircling the non-covalently bound mature TGF-β homodimer.
Mingliang Jin +6 more
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Frontiers in Bioengineering and Biotechnology, 2021 The application of amniotic membrane (AM) on chronic wounds has proven very effective at resetting wound healing, particularly in re-epithelialization. Historically, several aspects of AM effect on wound healing have been evaluated using cell models.
Catalina Ruiz-Cañada +5 more
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The TGF-β/NADPH Oxidases Axis in the Regulation of Liver Cell Biology in Health and Disease
Cells, 2021 The Transforming Growth Factor-beta (TGF-β) pathway plays essential roles in liver development and homeostasis and become a relevant factor involved in different liver pathologies, particularly fibrosis and cancer. The family of NADPH oxidases (NOXs) has
Macarena Herranz-Itúrbide +4 more
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Serum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet B [PDF]
American Journal of Applied Sciences, 2014 Although it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-I² and TNF-I ...
Ahmad Taha Khalaf, Yan Yuehua
openaire +1 more source
Dissecting the role of the NADPH oxidase NOX4 in TGF-beta signaling in hepatocellular carcinoma
Redox Biology, 2023 The NADPH oxidase NOX4 has been proposed as necessary for the apoptosis induced by the Transforming Growth Factor-beta (TGF-β) in hepatocytes and hepatocellular carcinoma (HCC) cells.
Rut Espinosa-Sotelo +17 more
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Role of TGF-β in Skin Chronic Wounds: A Keratinocyte Perspective
Cells, 2020 Chronic wounds are characterized for their incapacity to heal within an expected time frame. Potential mechanisms driving this impairment are poorly understood and current hypotheses point to the development of an unbalanced milieu of growth factor and ...
Sergio Liarte +2 more
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Cells, 2020 Defects in wound closure can be related to the failure of keratinocytes to re-epithelize. Potential mechanisms driving this impairment comprise unbalanced cytokine signaling, including Transforming Growth Factor-β (TFG-β).
Sergio Liarte +2 more
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THU0271 SERUM LEVELS OF TRANSFORMING GROWTH FACTOR î‘ (TGF-î‘) IN PATIENTS WITH PRIMARY SJÖGREN'S SYNDROME [PDF]
Annals of the Rheumatic Diseases, 2019 Background Primary Sjogren’s syndrome (pSS) is an autoimmune disease affecting primarily exocrine, especially salivary, glands. The epithelial damage, autoantigens release, activation of innate and acquired immunity form the underlaying of the pSS pathogenesis. The main role in pSS is played by B-lymphocytes and production of autoantibodies.
Maria Maślińska +4 more
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NADPH oxidase 4 (Nox4) deletion accelerates liver regeneration in mice
Redox Biology, 2021 Liver is a unique organ in displaying a reparative and regenerative response after acute/chronic damage or partial hepatectomy, when all the cell types must proliferate to re-establish the liver mass.
M. Herranz-Itúrbide +11 more
doaj +1 more source