Results 11 to 20 of about 320,405 (317)

Oleanolic acid rescues critical features of umbilical vein endothelial cells permanently affected by hyperglycemia

Frontiers in Endocrinology, 2023
Skin wound healing is a physiological process that involves several cell types. Among them, endothelial cells are required for inflammation resolution and neo‐angiogenesis, both necessary for tissue restoration after injury.
Javier Stelling-Férez, Javier Stelling-Férez, Ilaria Cappellacci, Assunta Pandolfi, José Antonio Gabaldón, Caterina Pipino, Francisco José Nicolás   +6 more
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SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4

Communications Biology, 2022
In pancreatic ductal adenocarcinoma cells and patient tissue, SMAD2/3 is shown to mediate oncogenic effects of TGF-β in the absence of SMAD4.
Adrien Bertrand-Chapel, Cassandre Caligaris, Tanguy Fenouil, Clara Savary, Sophie Aires, Sylvie Martel, Paul Huchedé, Christelle Chassot, Véronique Chauvet, Victoire Cardot-Ruffino, Anne-Pierre Morel, Fabien Subtil, Kayvan Mohkam, Jean-Yves Mabrut, Laurie Tonon, Alain Viari, Philippe Cassier, Valérie Hervieu, Marie Castets, Alain Mauviel, Stéphanie Sentis, Laurent Bartholin   +21 more
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Transforming Growth Factor (TGF) β and Endometrial Vascular Maturation

Frontiers in Cell and Developmental Biology, 2021
Appropriate growth and development of the endometrium across the menstrual cycle is key for a woman’s quality of life and reproductive well-being. Recurrent pregnancy loss (RPL) and heavy menstrual bleeding (HMB) affect a significant proportion of the ...
Qinsheng Lu, Dingqian Sun, Sourima Biswas Shivhare, Huomei Hou, Judith N. Bulmer, Barbara A. Innes, Dharani K. Hapangama, Gendie E. Lash   +7 more
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Measurement of Cell Intrinsic TGF-β Activation Mediated by the Integrin αvβ8

Bio-Protocol, 2022
Transforming growth factor beta (TGF-β) is a multi-functional cytokine that plays a significant role in multiple diseases, including fibrosis and tumor progression.
Robert Seed, Stephen Nishimura
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LY6K depletion modulates TGF‐β and EGF signaling

Cancer Medicine, 2023
Background Lymphocyte antigen 6 complex locus K (LY6K), a glycosylphosphatidylinositol‐anchored protein, plays a dynamic role in cancer metastasis.
Sujeong Park, Doyeon Park, Sora Han, Ga Eun Chung, Sujung Soh, Hye In Ka, Hyun Jeong Joo, Young Yang   +7 more
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IGFBP‐3 and TGF‐β inhibit growth in epithelial cells by stimulating type V TGF‐β receptor (TβR‐V)‐mediated tumor suppressor signaling

FASEB BioAdvances, 2021
The TGF‐β type V receptor (TβR‐V) mediates growth inhibition by IGFBP‐3 and TGF‐β in epithelial cells and loss of TβR‐V expression in these cells leads to development of carcinoma.
Chun‐Lin Chen, Franklin W. Huang, Shuan Shian Huang, Jung San Huang   +3 more
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Transforming growth factor-β: Biology and application to cancer therapy [PDF]

Archive of Oncology, 2009
Transforming growth factor-β (TGF-β), an extensively investigated cytokine, plays a very important role in promoting the spread of cancers in the body, and can play a direct role in facilitating metastasis.
Ivanović Vesna
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Pre-existing TGF-β-specific T-cell immunity in patients with pancreatic cancer predicts survival after checkpoint inhibitors combined with radiotherapy

Journal for ImmunoTherapy of Cancer, 2023
Background Circulating transforming growth factor-β (TGF-β)-specific T cells that recognize TGF-β-expressing immune regulatory cells have been described in patients with cancer.
Mads Hald Andersen, Özcan Met, Inge Marie Svane, Morten Orebo Holmström, Thomas Landkildehus Lisle, Rasmus Erik Johansson Mortensen, Jane P Hasselby, Gro L Willemoe, Julia Johansen, Dorte L Nielsen, Inna M Chen   +10 more
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Autocrine TGF-β Induces Epithelial to Mesenchymal Transition in Human Amniotic Epithelial Cells

Cell Transplantation, 2013
Human amniotic epithelial cells (hAECs) have been the object of intense research due to their potential therapeutic use. In this paper, we present molecular evidence of a bona fide epithelial to mesenchymal transition (EMT) undergone by hAECs.
Antonia Alcaraz, Anna Mrowiec, Carmen L. Insausti, Eva M. García-Vizcaíno, Catalina Ruiz-Canada, María C. López-Martínez, José M. Moraleda, Francisco J. Nicolás   +7 more
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Murine CD4 T cells produce a new form of TGF-β as measured by a newly developed TGF-β bioassay. [PDF]

PLoS ONE, 2011
It is generally assumed that T cells do not produce active TGF-β since active TGF-β as measured in supernatants by ELISA without acidification is usually not detectable. However, it is possible that active TGF-β from T cells may take a special form which
Takatoku Oida, Howard L Weiner
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