Results 181 to 190 of about 431,292 (339)

Additional file 2: of The transcription factor LEF1 promotes tumorigenicity and activates the TGF-β signaling pathway in esophageal squamous cell carcinoma

, 2019
Table S1. Correlation between LEF1 expression and clinicopathological characteristics in 243 patients. Table S2. Correlation between LEF1 expression and clinicopathological characteristics in total 338 patients. (DOCX 21 kb)
Zhao, Yue, Zhu, Ji, Shi, Bowen, Wang, Xinyu, Lu, Qijue, Li, Chunguang, Chen, Hezhong   +6 more
openaire   +1 more source

P3‐416: Differential TGF‐β‐Smad 2/3 and BMP‐Smad 1/5/8 pathway activation promotes macrophage Aβ phagocytosis [PDF]

, 2010
David Gate, Kavon Rezai‐Zadeh, Helen S. Goodridge, Javier Rodríguez, Dominique Jodry, David M. Underhill, Terrence Town   +6 more
openalex   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

Advanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang, Si‐Bo Yang, Yan Luo, Xiao‐Di Sun, Bo‐Hao Chang, Da‐Qiang Zhou, Jun‐Jie Jiang, Ya‐Nan Li, Jie‐Hong Wu, Hui‐Juan Jin, Hang Yang, Hang Hu, Yi‐Fan Zhou, Bo Hu   +13 more
wiley   +1 more source

Intratumoral immunotherapy with mRNAs encoding chimeric protein constructs encompassing IL-12, CD137 agonists, and TGF-β antagonists [PDF]

, 2023
Assunta Cirella, Elixabet Bolaños, Carlos Luri‐Rey, Claudia Augusta Di Trani, Irene Olivera, Gabriel Gomis, Javier Glez‐Vaz, Beatrice Pinci, Saray Garasa, Sandra Sánchez‐Gregorio, Arantza Azpilikueta, Iñaki Eguren‐Santamaría, Karmele Valencia, Belén Palencia, Maite Álvarez, María C. Ochoa, Álvaro Teijeira, Pedro Berraondo, Ignacio Melero   +18 more
openalex   +1 more source

Additional file 6: of Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1

, 2019
Table S1. Primers used for qRT-PCR (DOCX 16 kb)
Cen, Shuizhong, Wang, Peng, Xie, Zhongyu, Yang, Rui, Li, Jinteng, Liu, Zhenhua, Wang, Shan, Wu, Xiaohua, Liu, Wenjie, Li, Ming, Tang, Su’an, Shen, Huiyong, Wu, Yanfeng   +12 more
openaire   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

MOESM3 of Identification and validation a TGF-β-associated long non-coding RNA of head and neck squamous cell carcinoma by bioinformatics method

, 2018
Additional file 3. Demographics and clinical characteristics of TCGA HNSCC cohort.
Huang, Teng, Huang, Wei, Lu, Hong, Zhang, Bi-yun, Ma, Jun, Zhao, Di, Wang, Yi-jun, Yu, Da-hai, He, Xia   +8 more
openaire   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun, XueBo Wei, ZhuoYang Song, JunJun Luo, JingYi Ye, YinNan Zhang, LiFei Zhu, Jie Gao, Hongyu Zhang, Hong Zhu, Xin Wang, Ke Xu   +11 more
wiley   +1 more source

Transforming Growth Factor‐Beta Signaling in Cancer: Therapeutic Implications, Challenges, and Pathways to Progress

MedComm – Oncology
The transforming growth factor‐β (TGF‐β) family consists of evolutionarily conserved cytokines that regulate various physiological processes across nearly all tissue and cell types.
Faizah A. Alabi, Izuchukwu F. Okpalanwaka, Adenike Oyegbesan, Ebenezar Okoyeocha, Mariam Oladejo, Sikiru O. Imodoye   +5 more
doaj   +1 more source

In situ analysis of transforming growth factor-βs (TGF-β1, TGF-β2, TGF-β3and TGF-3 type II receptor expression in malignant melanoma [PDF]

, 2017
We have analysed, by in situ hybridization, mRNA expression of TGF-β1, TGF-β2, TGF-β3, and of TGF-β type II receptor in benign melanocytic naevi, primary melanomas, and in skin metastases of malignant melanomas. Our results show that melanoma progression
Itin, Peter, Rufli, Theo, Schmid, Peter
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