Serum TGF-β and TNF-α During Psoriasis Therapy with Narrowband Ultraviolet B [PDF]
American Journal of Applied Sciences, 2014 Although it is now an accepted concept that narrow-band UVB therapy is an efficacious therapy for psoriasis, the relationship between the response rate and the potential effects on serum cytokines is less well-established. The purpose of this study was to investigate the correlation between the response rate and the changes of serum TGF-I² and TNF-I ...
Ahmad Taha Khalaf, Yan Yuehua
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THU0271 SERUM LEVELS OF TRANSFORMING GROWTH FACTOR î‘ (TGF-î‘) IN PATIENTS WITH PRIMARY SJÖGREN'S SYNDROME [PDF]
Annals of the Rheumatic Diseases, 2019 Background Primary Sjogren’s syndrome (pSS) is an autoimmune disease affecting primarily exocrine, especially salivary, glands. The epithelial damage, autoantigens release, activation of innate and acquired immunity form the underlaying of the pSS pathogenesis. The main role in pSS is played by B-lymphocytes and production of autoantibodies.
Maria Maślińska +4 more
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SMAD2/3 mediate oncogenic effects of TGF-β in the absence of SMAD4
Communications Biology, 2022 In pancreatic ductal adenocarcinoma cells and patient tissue, SMAD2/3 is shown to mediate oncogenic effects of TGF-β in the absence of SMAD4.
Adrien Bertrand-Chapel +21 more
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Transforming Growth Factor (TGF) β and Endometrial Vascular Maturation
Frontiers in Cell and Developmental Biology, 2021 Appropriate growth and development of the endometrium across the menstrual cycle is key for a woman’s quality of life and reproductive well-being. Recurrent pregnancy loss (RPL) and heavy menstrual bleeding (HMB) affect a significant proportion of the ...
Qinsheng Lu +7 more
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Measurement of Cell Intrinsic TGF-β Activation Mediated by the Integrin αvβ8
Bio-Protocol, 2022 Transforming growth factor beta (TGF-β) is a multi-functional cytokine that plays a significant role in multiple diseases, including fibrosis and tumor progression.
Robert Seed, Stephen Nishimura
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TGF-β-responsive CAR-T cells promote anti-tumor immune function. [PDF]
, 2018 A chimeric antigen receptor (CAR) that responds to transforming growth factor beta (TGF-β) enables the engineering of T cells that convert this immunosuppressive cytokine into a potent T-cell stimulant.
Chang, ZeNan L +4 more
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LY6K depletion modulates TGF‐β and EGF signaling
Cancer Medicine, 2023 Background Lymphocyte antigen 6 complex locus K (LY6K), a glycosylphosphatidylinositol‐anchored protein, plays a dynamic role in cancer metastasis.
Sujeong Park +7 more
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Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]
, 2011 Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey +39 more
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HGF modulates actin cytoskeleton remodeling and contraction in testicular myoid cells [PDF]
, 2015 The presence of the HGF/Met system in the testicular myoid cells was first discovered by our group. However, the physiological role of this pathway remains poorly understood. We previously reported that HGF increases uPA secretion and TGF-β activation in
Angela, Catizone +6 more
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FASEB BioAdvances, 2021 The TGF‐β type V receptor (TβR‐V) mediates growth inhibition by IGFBP‐3 and TGF‐β in epithelial cells and loss of TβR‐V expression in these cells leads to development of carcinoma.
Chun‐Lin Chen +3 more
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