Results 231 to 240 of about 320,405 (317)
Proximal TGF-β Signaling in Chronic Injury: from a notorious fibrotic factor to a repair ally. [PDF]
Pflugers ArchNlandu Khodo S.
europepmc +1 more source
Matrix Stiffness Induces Endothelial Network Senescence
Advanced Science, EarlyView.Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song +6 more
wiley +1 more source
ATG7 vs. ATG5: Distinct autophagy pathways shaping TGF-β signaling and endothelial function. [PDF]
PLoS OneSingh A +4 more
europepmc +1 more source
Advanced Science, EarlyView.We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo +7 more
wiley +1 more source
GnRH Regulates Sex Differentiation in <i>Sebastes schlegelii</i> Through TGF-β/MAPK Signaling Pathways. [PDF]
Biology (Basel)Huang J, Xu P, Xiao Y, Li J.
europepmc +1 more source
THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome
Advanced Science, EarlyView.The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong +16 more
wiley +1 more source
Role of IFN-γ and TGF-β in the Pathophysiology of Chronic Sinusitis :. [PDF]
Galen Med JKhalaf AS, Alwan AM, Khalaf AS.
europepmc +1 more source